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      community Anyone else realize how many younger guys are balding?

      in Chat  262 upvotes 1 month ago
      Many younger men are experiencing hair loss due to genetics, diet, stress, and lifestyle changes. Treatments like finasteride and minoxidil are mentioned, with some users noting improvements.

      community FINASTRIDE and switch to DUTASTRIDE, my experience

      in Progress Pictures  134 upvotes 2 months ago
      The user shared their experience with Finasteride and Dutasteride for hair loss. They initially had success with Finasteride but switched to Dutasteride after experiencing shedding, which continued, and are now considering a hair transplant.

      community Dutasteride is for Young Hair Loss Suffers

      in Finasteride/Dutasteride  104 upvotes 2 months ago
      Dutasteride is discussed as a treatment for young hair loss sufferers, with mixed experiences regarding side effects and effectiveness. Some users report positive results with Dutasteride, while others prefer Finasteride or Minoxidil due to fewer side effects.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 2 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community 11 months on fin + min. Thoughts?

      in Progress Pictures  918 upvotes 2 months ago
      A user shared progress pictures after 11 months on finasteride and minoxidil, with intermittent microneedling. The community responded positively, noting significant hair regrowth and encouraging continued treatment.

      community Minoxidil For 2 Years, What is this?

      in Treatment  111 upvotes 2 months ago
      The user has experienced significant hair thinning despite using 2.5 mg minoxidil for 2 years. Other users suggest adding finasteride or dutasteride and consulting a dermatologist for a proper diagnosis.
      Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI?

      community Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI?

      in Treatments  372 upvotes 2 months ago
      Topical dutasteride is suggested as a low side-effect treatment for hair loss, with a proposed dose of 0.025% 1ml/day. It is considered better than finasteride due to its even inhibition of DHT isoforms and lower systemic absorption.

      community Rosemary out here changing lives for the better

      in Treatment  90 upvotes 4 months ago
      Rosemary oil is being used as an addition to minoxidil and finasteride for hair health, with mixed opinions on its effectiveness. Some users report positive results, while others see no benefit or experience adverse effects.

      community Comparison of options: topical vs medication

      in Female  1 upvotes 5 months ago
      A user diagnosed with AGA is seeking advice on hair loss treatments, comparing topical Minoxidil, Spironolactone, and Finasteride to oral medications and natural methods like dermastamping, PRP, and LED light. They are concerned about side effects and effectiveness, especially given their existing fatigue.

      community Topical Dutasteride. Does it work?

      in Finasteride/Dutasteride  13 upvotes 5 months ago
      Topical dutasteride may be effective for hair loss by staying in the scalp and minimizing bloodstream absorption, potentially improving hair results and reducing side effects. The user seeks advice on its effectiveness.

      community HMI 115 Phase 2 - Leaked pics from Discord

      in Research/Science  361 upvotes 6 months ago
      The conversation discusses HMI 115, a new hair loss treatment with promising results, showing a significant increase in hair density after two months. Some users are skeptical, while others are hopeful for its release and potential affordability.

      community Quit vaping/smoking = 80% less loss

      in Research/Science  235 upvotes 7 months ago
      Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

      community Reasons why Topical worked but Oral Minoxidil didn’t?

      in Minoxidil  16 upvotes 8 months ago
      Some people find topical minoxidil effective for hair loss, but oral minoxidil doesn't work for them, possibly due to absorption issues. Others have had better results with oral minoxidil, suggesting individual responses vary.

      community Male pattern baldness, and mental health

      in Finasteride/Dutasteride  326 upvotes 9 months ago
      A 48-year-old man has been using minoxidil for 15 years and considered finasteride but stopped due to potential side effects. He is concerned about his mental health and the impact of hair loss on self-image, and he encourages support among men experiencing hair loss.

      community Exploring Bryan Johnson's Hair Routine In Detail

      in Research/Science  63 upvotes 10 months ago
      Bryan Johnson uses a custom hair loss treatment that includes topical finasteride, minoxidil, azelaic acid, diclofenac, tea tree oil, rosemary oil, ginkgo biloba, biotin, and melatonin, which have shown varying degrees of effectiveness with minimal side effects. He also undergoes PRP and laser therapy, and has tried dutasteride mesotherapy.

      community If RU58841 is such an effective anti androgen

      in Research/Science  46 upvotes 10 months ago
      RU58841 is discussed as a topical anti-androgen for hair loss, but its effectiveness and safety are not well-documented, leading to mixed opinions and experiences among users. Some combine it with finasteride, but concerns about side effects and lack of FDA approval limit its popularity.

      community I just made my own PRP - DIY PRP

      in Research/Science  545 upvotes 1 year ago
      The post and conversation are about a user who made their own Platelet-Rich Plasma (PRP) for hair loss treatment at home, using their own blood and a centrifuge. The responses vary, with some users supporting the DIY approach to save money, others expressing concern about the safety and effectiveness of the method, and a few joking about the lengths people will go to combat hair loss.