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A user is considering using RU58841 for female pattern baldness and is also planning to use Minoxidil. They are hesitant to ask their doctor for spironolactone due to its cosmetic nature and are experiencing significant hair loss possibly due to stress and hormonal issues.

CRISPR treatments for blood disorders have been approved, leading to discussions about its potential for treating hair loss (AGA). A study showed that editing a gene related to DHT sensitivity could lead to hair regrowth, suggesting CRISPR may eventually be used for AGA, but it's expected to be expensive and not soon available.

The user has been experiencing hair loss since having COVID and has low vitamin D levels; they are seeing some improvement in their crown and hairline after starting vitamin D supplements. Commenters suggest the hair loss pattern is consistent with male pattern baldness (MPD) and varies by individual.

Pyrilutamide, a potential topical treatment for male pattern baldness, and the user's anticipation of its Phase 2 trial results. Several users discussed their experiences with Finasteride and RU58841, while others voiced skepticism about the efficacy of Pyrilutamide.

The safety of using oral minoxidil to treat hair loss and thinning, with studies showing mild side effects at low doses. It was suggested that people should consult a doctor or dermatologist before taking any type of medication for hair loss.

A person in their 20s is struggling with hair loss, using treatments like minoxidil and finasteride. Suggestions include self-improvement, therapy, hair transplants, and focusing on acceptance and confidence.

A 25-year-old user shared progress pictures after 16 months of using 1.25mg daily finasteride for hair loss, reporting noticeable results around months 4-5 and some initial side effects that resolved. The user experienced thickening and slight regrowth of the hairline.

A user shared positive results after 3 months of using 1 mg finasteride and 5% topical minoxidil daily for hair regrowth. Other users expressed amazement and shared similar experiences, with one noting potential shedding around months 5-7.

The DHT itch is linked to hair loss and persists despite finasteride use; switching to dutasteride helped alleviate the itch and promoted regrowth. Some users suggest seborrheic dermatitis as a cause and recommend treatments like medicated shampoos, vitamin D, and minoxidil.

A user is seeking advice on hair loss treatment and has been prescribed finasteride. They currently use minoxidil, rosemary oil, and castor oil, and are considering adding dermarolling. Respondents suggest daily use of minoxidil and finasteride, with some recommending additional treatments like ketoconazole shampoo, dermapen, dutasteride, and vitamins.

A user is starting topical finasteride and minoxidil 3 times a week for hair loss and is experiencing high anxiety about the treatment's effectiveness and potential side effects. They are also taking vitamin D3 daily and are concerned about the application method and possible shedding.

A user shared a 9-month update on hair loss treatment, reporting positive results from taking 1 mg of finasteride and 1.25 mg of minoxidil daily. The discussion includes varied experiences with these treatments, questions about side effects, and comments on the unpredictability of treatment effectiveness.

The conversation discusses whether to try dutasteride for hair loss if finasteride had no effect. Users suggest dutasteride might be more effective as it is stronger and blocks more types of DHT.

Oral minoxidil has gained popularity as a hair loss treatment, with more online discussions and research showing it's safe in low doses. A viral New York Times article also contributed to its increased acceptance.

An 18-year-old has been using topical finasteride and minoxidil for hair loss without noticeable improvement and is considering oral finasteride. Some users suggest starting oral finasteride at 18 is fine, especially if puberty is complete, while others recommend caution and consulting a specialist.

A 23-year-old started using 1mg Finasteride and Minoxidil twice daily on September 14 and saw positive results without side effects, boosting confidence and gym performance. They asked if switching from generic Finasteride to Propecia-brand would cause any changes.

A user shared their successful hair regrowth using a combination of minoxidil, caffeine, biotin, and RU58841, along with weekly dermarolling. However, others advised against the user's plan to switch to rosemary oil and microneedling only, emphasizing the importance of continuing the current treatment to maintain the results.

Isotretinoin may cause hair loss by increasing DHT through a precursor androgen, DHEAS. Treatments like topical antiandrogens (RU58841, pyrilutamide) and drugs increasing PPAR-y expression (pioglitazone) might prevent this hair loss.

Onion juice, when applied topically, is an effective treatment for Alopecia Areata, showing significant hair regrowth in both males and females. The study suggests it could be interesting to test its effectiveness on Androgenic Alopecia.

Hair loss discussion mentions Verterporfin for scar-free healing and hair follicle regeneration. Human study expected within 2 years.

Spudlady asks about experiences with spironolactone for hair loss. She has lost hair due to stress and seeks ways to stop shedding.

User shares 3-month progress using Fin, Minox, Nizoral, and dermarolling for hair loss. Others praise results, discuss dermarolling, and suggest continued treatment for full coverage.

The user experienced increased hair density and thickness after 3-4 months using finasteride, minoxidil, dermastamping, ketoconazole, and biotin. They apply minoxidil right after dermastamping without any side effects or shedding.

Microneedling before a hair transplant may harden the scalp and affect blood circulation, potentially impacting graft growth. Some users report successful transplants after microneedling, while others advise caution and consulting with a surgeon.

FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

A user shared progress pictures after 11 months on finasteride and minoxidil, with intermittent microneedling. The community responded positively, noting significant hair regrowth and encouraging continued treatment.

The user has experienced significant hair thinning despite using 2.5 mg minoxidil for 2 years. Other users suggest adding finasteride or dutasteride and consulting a dermatologist for a proper diagnosis.

A user shared their 3-year experience using finasteride for hair loss, reporting significant improvement and no side effects. They are now starting dutasteride and plan to update on progress in a year.

Topical dutasteride may be effective for hair loss by staying in the scalp and minimizing bloodstream absorption, potentially improving hair results and reducing side effects. The user seeks advice on its effectiveness.