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      community Clascoterone 5% Delivers Strong Phase 3 Hair-Growth Results

       371 upvotes 8 months ago
      Clascoterone 5% solution shows strong potential for hair growth, offering a new treatment for alopecia with minimal side effects. It blocks androgen receptors locally and may be available by late 2026 or early 2027.

      community Clascoterone phase 3 results are out!

       80 upvotes 9 months ago
      Clascoterone phase 3 results show promising improvements in hair count, but concerns about high costs and lack of detailed data remain. Users compare it to existing treatments like Minoxidil and Finasteride, expressing skepticism about its accessibility and effectiveness.

      community Topicals for sensitive scalp (+sed derm)

       9 upvotes 2 months ago
      The conversation is about finding a gentle topical treatment for a sensitive scalp with seborrheic dermatitis. Suggestions include using Trichosol/Trichofoam-based topical finasteride/minoxidil, which is considered gentle on the scalp.

      community Why are there no FDA approved NSAA's yet?

      in Research/Science 2 years ago
      The conversation discusses why there are no FDA-approved NSAAs like RU58841 on the market, despite their potential superiority to 5AR inhibitors like finasteride. It explores the effectiveness of treatments like Minoxidil, finasteride, and RU58841 for hair loss.

      community GT-20029 should be much more superior than finasteride

       39 upvotes 1 year ago
      GT-20029 is discussed as a potential hair loss treatment, with concerns about its safety and systemic absorption compared to finasteride. Users express skepticism about its effectiveness and safety, noting that it may not surpass existing treatments like finasteride and minoxidil.

      community Clascoterone for hair loss. Promising study.

       11 upvotes 9 months ago
      A new topical medication, Clascoterone, shows promise for hair loss, improving hair count significantly. Trials for Breezula are ending, but sign-ups for PP405 trials are available for 2026.

      community Caffeine & Alopecia: What the Science Seems to Say

       18 upvotes 2 years ago
      The conversation discusses the potential benefits of topical caffeine for Androgenetic Alopecia (APA) and female pattern hair loss. While some studies suggest positive results, there's no reliable scientific evidence to strongly recommend caffeine compounds for hair regrowth.

      community RCP (redensyl, capixyl, procapil) combination over minoxidil long term?

       4 upvotes 5 years ago
      The conversation discusses using a combination of redensyl, capixyl, and procapil (RCP) for hair loss, with some users also mentioning minoxidil and finasteride. Users shared mixed experiences, with some suggesting "RevivHair Max Hair Stimulating Serum" for better results, while others reported no noticeable effects from using products like The Ordinary Multi-Peptide Serum.

      community Black light diagnosis of folliculitis

       3 upvotes 1 month ago
      A user observed orange fluorescence on their nose and hair under a black light, indicating Cutibacterium acnes, which may contribute to hair loss alongside androgenic alopecia. A suggestion was made to use coal tar shampoo to address the issue.

      community What's your opinion on topical caffeine serum?

      in Treatment  4 upvotes 1 year ago
      The conversation discusses the effectiveness of adding topical caffeine serum to a hair loss treatment routine that includes minoxidil and finasteride. Users suggest alternatives like stemoxidine, alphatradiol, and pyrilutamide, noting that evidence for caffeine's effectiveness is weak.

      community PP405 is out for sale on everychem.

       94 upvotes 1 year ago
      PP405 is suspected to be a scam, with users doubting its legitimacy and effectiveness. Many recommend using proven treatments like finasteride and minoxidil.

      community Just a PSA for all of your benefits

       8 upvotes 9 years ago
      Maintaining a healthy lifestyle, including proper diet and exercise, is crucial for maximizing hair growth alongside treatments like finasteride, minoxidil, and ketoconazole shampoos. Key recommendations include meeting iron and protein requirements, avoiding smoking, and addressing thyroid issues.

      community Looking for real-world experiences with Kadeso

       3 upvotes 1 year ago
      A user is exploring Kadeso, a product with Capilia Longa™ for hair regrowth, and seeks real-world experiences, comparing it to Minoxidil and Finasteride. They are interested in results, timeframe, side effects, and the credibility of the product's founder.

      community Where is GT20029 already? Grrrr

       19 upvotes 2 years ago
      The conversation is about frustration over the delay in phase 2 results for a hair loss treatment called GT20029. One user suspects the treatment may have failed.

      community Chat is this real? Compound called clascoterone

       581 upvotes 9 months ago
      Clascoterone shows promising results for hair regrowth in men with androgenetic alopecia, with potential FDA approval by 2026. It acts as a topical androgen receptor blocker, offering a new treatment option with minimal side effects compared to existing treatments like finasteride.

      community Clascoterone - what we have right now

       24 upvotes 6 months ago
      Clascoterone is a topical treatment for androgenetic alopecia, showing modest to moderate hair regrowth, and may be available by 2027-2028. It is considered safer than finasteride, with discussions on its effectiveness compared to RU58841 and pyrilutamide.

      community Clascoterone 5% solution infographic

       130 upvotes 9 months ago
      Clascoterone 5% solution is discussed as a potential new treatment for hair loss, offering an alternative for those who can't use finasteride or need additional options beyond minoxidil. Concerns about cost, effectiveness, and safety compared to existing treatments like RU58841 and finasteride are highlighted.

      community Approve PP405 quickly you coward

      in Satire  193 upvotes 1 year ago
      Pelage Pharmaceuticals is developing PP405, a topical treatment for hair growth, currently in Phase 2a trials. There is skepticism about the company's claims, and no fast-tracking approval timeline has been detailed.

      community Stopping min on scalp - psoriasis

      in Minoxidil  35 upvotes 1 year ago
      A user with mild psoriasis on the scalp is using finasteride, topical minoxidil, and dermarolling for hair loss but plans to stop minoxidil on the crown due to psoriasis aggravation. Suggestions include switching to a lipid-based minoxidil, using Ketoconazole shampoo, or trying oral minoxidil.

      community Why is everyone still arguing about PP405 when clascoterone is already heading toward regulatory submission?

       46 upvotes 1 month ago
      Clascoterone is nearing regulatory submission as a potential new treatment for androgenetic alopecia, with positive Phase III results, while discussions continue about other treatments like PP405, minoxidil, and finasteride. Some users express excitement for clascoterone and Breezula, despite concerns about the effectiveness and practicality of topical treatments.

      community Anyone see this new pp405 site?

      in Product  5 upvotes 1 year ago
      A new hair growth product called PP405 is discussed, with skepticism about its legitimacy. Users express doubts about the product's authenticity and consider it potentially a scam.

      community Terrible experience with MV Supplements and no support

       4 upvotes 2 years ago
      A user had a bad experience with MV Supplements when their Pyril powder and ethanol order leaked during shipping, making the products unusable. Despite contacting support and providing evidence, the company's return policy did not allow for a refund or replacement.

      community Got prescribed clobetasol propionate 0.05%

       5 upvotes 5 days ago
      The user is experiencing diffuse thinning and receded hairline, using dutasteride, minoxidil, and ketoconazole without regrowth, and was prescribed clobetasol propionate 0.05% with salicylic acid for possible inflammation. Other users caution against using the strong steroid without a serious condition, sharing experiences of adverse effects and alternative treatments for scalp issues.

      community Dr. Rassman vs Kevin Mann on Eucapil

       4 upvotes 5 years ago
      Eucapil is discussed as a potential hair loss treatment with some believing it to be effective, though its efficacy compared to finasteride is debated. It is considered an anti-androgen treatment, often used alongside other treatments like minoxidil and finasteride, but lacks independent studies to fully support its effectiveness.

      community Wanting to try topical AHK-CU/GHK-CU

       6 upvotes 3 months ago
      The user is exploring topical treatments AHK-CU and GHK-CU for hair loss, avoiding Minoxidil and prescription medications. They believe their hair loss is not genetic but caused by Accutane, and are considering products like Neurogan and Bloom by Fleur.

      community Chinese source for pyrilutamide or ru8841 ?

       3 upvotes 11 months ago
      The conversation is about finding a reliable Chinese source for pyrilutamide or RU58841, ideally with a third-party Certificate of Analysis from Janoshik Analytical. The user is seeking recommendations for these hair loss treatments.