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      community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

       63 upvotes 2 years ago
      Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

      community Is the minoxidil working on my crown?

      in Minoxidil  10 upvotes 1 month ago
      The user has been using minoxidil and dutasteride for hair loss, noticing some improvement in hair density but considering adding tretinoin to enhance results. Suggestions include trying oral minoxidil, dermarolling, and ketoconazole shampoo for potential seborrheic dermatitis.

      community Any chemists want to manufacture PP405 / JXL069? (Steps inside)

       114 upvotes 1 year ago
      The conversation discusses the potential of PP405 as a hair loss treatment, with some users expressing skepticism and others hopeful about its development. There is also mention of other treatments like Minoxidil, Finasteride, and Pyrilutamide, with users debating the effectiveness and safety of self-experimentation versus waiting for clinical trial results.

      community Dut mesotherapy shed or not working

      in Finasteride/Dutasteride  1 upvotes 1 year ago
      The user experienced initial success with topical minoxidil and dutasteride mesotherapy but is now losing more hair and unsure if it's due to shedding or ineffective treatment. They are considering whether to try a different approach.

      community 23m is this progress or not ….

      in Is this regrowth?  24 upvotes 11 months ago
      The user experienced hair regrowth using minoxidil and finasteride but reported scalp itching, possibly due to the liquid form of minoxidil. They also use ketoconazole shampoo to manage flakes, which they clarify are not dandruff.

      community "DHT Itch" and onset Seborrheic Dermatitis

      in Research/Science  76 upvotes 2 years ago
      The post and conversation discuss the link between DHT (a hormone), scalp itchiness, and hair loss. Some users share their experiences and treatments, including the use of fluconazole, corticosteroids, and ketoconazole shampoo, with one user suspecting minoxidil as a potential cause of their symptoms.

      community The never ending cycle as a fin+min user

       1356 upvotes 2 weeks ago
      Hair loss treatments like finasteride and minoxidil can cause cycles of shedding and regrowth, leading to fluctuating emotions. Users experience periods of hair improvement followed by shedding, with some finding long-term stabilization elusive.

      community Duasteride and breast tissue accumulation.

       4 upvotes 6 months ago
      The user is experiencing breast tissue growth from taking dutasteride and minoxidil, and is considering reducing the dosage or stopping the medication. Suggestions include seeing an endocrinologist, using Raloxifene or Arimidex, and considering topical treatments or surgery if necessary.

      community No shedding but temples & frontal receeding

      in Finasteride/Dutasteride 11 months ago
      A 24-year-old male started using finasteride and minoxidil for hair loss, noticing reduced hair fall but continued temple and frontal recession. He uses both oral and topical minoxidil, biotin, vitamin D, and coal tar shampoo, and experiences rare heart palpitations.

      community Got a quote for 3k grafts - how much will that actually cover?

      in Transplants  4 upvotes 1 month ago
      A user is considering a hair transplant with 3,000 grafts for mid-scalp and crown coverage, but there is skepticism about whether this will provide sufficient density. The user has been using treatments like finasteride and minoxidil for 10 years, which have slowed hair loss.

      community Is it harder to notice new growth with long hair?

      in Styling  3 upvotes 1 year ago
      The user is experiencing hair loss and is considering using finasteride again, along with ketoconazole shampoo and curl cream, to manage their long hair. They are concerned about the appearance of new hair growth and the potential shedding phase from minoxidil.

      community 16 and diffuse thinning, screw this

      in Minoxidil  14 upvotes 10 months ago
      A 16-year-old experiencing diffuse hair thinning is considering using minoxidil and plans to start finasteride at 18, while others suggest alternatives like saw palmetto and pumpkin seed oil. Users advise consulting a doctor before starting treatments and emphasize the importance of understanding the cause of hair loss.

      community 1 year 3 months finasteride and back to the drawing board..

       5 upvotes 4 years ago
      The user has been using finasteride for over a year, which improved their hairline but not the crown area. They are considering alternatives like hair fibers, derma stamping, or possibly minoxidil, while avoiding topicals due to their work environment.

      community How much faith do you have in Kintor?

       18 upvotes 4 years ago
      KX-826 is a potential hair loss treatment, with users discussing its effectiveness compared to finasteride and concerns about its trial results. Some users express skepticism about new treatments, while others discuss the potential of androgen receptor degraders and the need to manage drug resistance.

      community TDM-105795 phase 2 results are in!

       27 upvotes 2 years ago
      TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.

      community I had GPT create a comparison of pp405 week 8 results vs Fin and Min

       1 upvotes 1 year ago
      PP405 shows significantly better early-stage hair regrowth results compared to minoxidil and finasteride, with 31% of users experiencing over 20% density increase in 4–8 weeks. Minoxidil and finasteride show minimal or no visible regrowth in the same timeframe.

      community Am I balding or is it just a mature/natural hairline?

       4 upvotes 7 years ago
      The user is concerned about a receding hairline and is using finasteride, minoxidil, biotin, and derma rolling to address it. They are considering a hair transplant if these treatments don't work.

      community KX-826 alone to stop hairloss???

       13 upvotes 10 months ago
      A 28-year-old male experiencing early male pattern baldness is considering using Pyrilutamide (KX-826) as an alternative to finasteride due to side effects. He seeks to maintain his current hair without regrowth and is concerned about potential side effects like reduced libido.

      community The pessimism about the Crisp Cas 9 is excessive

       12 upvotes 11 months ago
      CRISPR Cas9 could potentially treat baldness by targeting specific genes in hair follicles without affecting other body functions. There is optimism about its future use, despite ethical concerns and the current reliance on treatments like minoxidil and finasteride.

      community What alternatives exist for Octa Sabal Plus?

       1 upvotes 5 years ago
      The conversation is about finding alternatives to Octa Sabal Plus for hair loss treatment. It mentions using ingredients like pumpkin seed oil, octacosanol, and soybean extract, but suggests finasteride as a more effective option.