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GlossaryStratum Corneum (Cornified Layer)

outermost skin layer composed of dead, keratinized cells

The Stratum Corneum, also known as the Horny Layer, is the outermost layer of the epidermis, consisting of dead, flattened skin cells that are rich in keratin. This layer acts as a primary barrier to protect underlying tissues from infection, dehydration, and mechanical stress, playing a crucial role in maintaining skin hydration and overall health.

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community Topical tretinoin increases minoxidil absorption by 3x. Thoughts?

in Minoxidil 39 upvotes 5 years ago

Topical tretinoin can increase the absorption of minoxidil by three times, which may enhance its effectiveness for hair loss treatment. Tretinoin causes increased skin turnover, making the skin more permeable and potentially improving minoxidil's efficacy.

community 17 month update 30M FUT 2300 grafts 1 year fin/min topical

in Progress Pictures 414 upvotes 10 months ago

A user shared a 17-month update on their hair loss treatment, which included a hair transplant of 2300 grafts, using a topical solution of minoxidil and finasteride, a laser cap, and ketoconazole shampoo. They are considering another transplant and seeking honest feedback on their progress, while others share their own experiences and advice on hair loss treatments.

community I’m really tired of using minoxidil

in Minoxidil 42 upvotes 1 year ago

The user is frustrated with minoxidil's lack of results and is considering alternatives like oral minoxidil or finasteride despite concerns about side effects. Other suggestions include consulting a doctor, adjusting dosages, or considering a hair transplant.

community 3 months progress with Finasteride 0.5mg/daily, Minoxidil foam5% 2x daily, Stemoxydine 2x daily, Microneedling(M8) 1.5mm 1x per week, Saw Palmetto 400mg/day, peppermint and jojoba oils daily, Ketoconazole 2% shampoo 3x/week, Purador shampoo/conditioner every day.

in Progress Pictures 337 upvotes 2 years ago

Jordan-Iliad has been using a combination of finasteride, minoxidil, stemoxydine, microneedling, saw palmetto, peppermint and jojoba oils, ketoconazole shampoo, and Purador shampoo/conditioner for 3 months to treat their hair loss with stunning results. They have also recently started taking oral minoxidil 1.25mg/day in hopes of achieving even better results over the next 3 months.

community Derm prescribed ketoconazole 2% shampoo, claiming my case “is not bad enough yet” for fin. Second opinion?

in Treatment 85 upvotes 1 year ago

A user was prescribed ketoconazole shampoo by their dermatologist for early-stage hair loss, but is unsure if this is the right treatment. Most commenters suggest seeking a second opinion or starting finasteride treatment immediately, while a few caution about potential side effects.

community Why is Minoxidil not enough for hair loss? (No fin)

in Minoxidil 57 upvotes 1 week ago

Minoxidil alone is often insufficient for treating hair loss because it doesn't address the DHT-related cause. Combining it with finasteride, a DHT blocker, is generally more effective.

community Are permanent hair gains even possible?

in Chat 14 upvotes 1 month ago

Hair regrowth from treatments like minoxidil, RU58841, and finasteride is not permanent; stopping these treatments typically results in hair loss resuming. Beard hair can become permanent with minoxidil use, unlike scalp hair, which requires ongoing treatment to maintain gains.

community PSA: Caffeine and Hair Transplants

in Transplants 28 upvotes 4 months ago

A user shared their experience with a hair transplant, emphasizing the importance of avoiding caffeine 7 days before the procedure. Ignoring this advice led to reduced effectiveness of the numbing agent, causing significant discomfort during the transplant.

community Finasteride shed is crazy at 7 months

in Finasteride/Dutasteride 30 upvotes 1 year ago

The conclusion of the conversation is that experiencing shedding while using finasteride and minoxidil is a common occurrence, and it is likely a part of the hair growth cycle. Many users have reported regrowth and improvement in their hair density after the shedding phase.

community 28M Dut 5x week [19 months] Before-After

in Progress Pictures 159 upvotes 1 year ago

User shared before and after photos of hair regrowth using Dutasteride 5x a week for 19 months. They experienced significant improvement and thanked others for their support.

community All in restoration Hair transplant from Dr Serkan in Turkey + topical fin/min Viviscal,biotin,sulfate free shampoo and Nizoral…very happy with results

in Progress Pictures 93 upvotes 2 years ago

A successful hair transplant with 3100 grafts combined with topical finasteride, minoxidil, Viviscal, biotin, sulfate free shampoo and Nizoral. People in the conversation talk about how the results look perfect and discuss the number of grafts and cost involved.

community Guide: How to EASILY get prescription oral minoxidil

in Minoxidil 21 upvotes 2 years ago

The conversation provides a six-step guide on how to get a prescription for oral minoxidil (OM) for hair loss by finding a supportive dermatologist, even if they are not local, and preparing a case for its use during a virtual consultation. The guide emphasizes the importance of research, insurance considerations, and the potential for initial hair shedding with OM treatment.

community My DHT levels have increased after taking 0.25mg Fin for 47 days!

in Finasteride/Dutasteride 185 upvotes 1 month ago

A user experienced increased hair shedding and unchanged DHT levels after taking 0.25mg of finasteride for 47 days, leading them to increase the dose to 0.5mg. Others discussed varying experiences with finasteride, minoxidil, and the importance of measuring scalp DHT.

community 18-year progress pics. Fin only.

in Progress Pictures 419 upvotes 2 months ago

The user has been using finasteride for 18 years to manage hair loss and is considering starting minoxidil and possibly a hair transplant. Despite some regrowth, they are exploring additional treatments like dutasteride and oral minoxidil due to continued hair thinning.

community I have hairy legs and arms, and the hair grows 2+ inches long- Can I transplant it all to my head?

in Transplants 442 upvotes 4 months ago

The conversation discusses the possibility of transplanting leg and arm hair to the scalp for hair loss treatment. Minoxidil is mentioned as a potential aid for hair growth, but concerns about the effectiveness and appearance of body hair on the head are raised.

community Why is it "not right" to start off with Dutasteride?

in Finasteride/Dutasteride 60 upvotes 5 months ago

The conversation discusses whether it's better to start hair loss treatment with finasteride or dutasteride. Opinions vary, but many suggest starting with finasteride due to its shorter half-life and easier management of side effects, while others argue dutasteride is more effective and has fewer side effects.

community Progress so far after a little over a year (23M)

in Progress Pictures 2755 upvotes 6 months ago

A 23-year-old shared his hair regrowth progress after using Minoxidil, finasteride, Dutasteride, and RU58841 for over a year. The post received supportive comments, with others sharing their own experiences and complimenting his transformation.

community Seeking Advice: Unusual Hair Loss at 31 Years Old - Any Insights? (M)

in Chat 15 upvotes 8 months ago

A 31-year-old man who previously had good results with minoxidil, finasteride, and nizoral for hair loss is now experiencing unusual hair loss and side effects from finasteride. Respondents suggest it might be severe retrograde alopecia and recommend exploring other treatment options due to his inability to tolerate finasteride.

community 25 Years old. 3 Months on Fin/Min, plus Hair & Nail Vitamins.

in Progress Pictures 379 upvotes 1 year ago

The conclusion of the conversation is that the user, Lead_Tasso, is expressing gratitude for the community's help in restoring their confidence in treating hair loss. They have been using finasteride (fin) and minoxidil (min) and have also been taking hair and nail vitamins.

community Can someone explain why it's "dumb" to just drink topical liquid minoxidil?

in Minoxidil 27 upvotes 1 year ago

The conversation discusses the risks and methods of ingesting liquid minoxidil for hair loss. Concerns include dosing accuracy, safety of ingredients, and potential side effects compared to using oral minoxidil tablets.

community Started rosemary oil in mid Feb. quickly moved to oral min, topical min, Dut, RU, derma rolling. And keto. Top pic is March 6. Bottom is today. 40 years old.

in Progress Pictures 213 upvotes 1 year ago

User started with rosemary oil, then used oral minoxidil, topical minoxidil, dutasteride, RU58841, derma rolling, and keto for hair loss treatment. Significant progress was made, and others praised the aggressive approach.

community (26M) My 3 months progress on hair loss treatment. Extremely happy with the results. I have included so many details about my stack, my experience during the treatment, progress pictures, and everything I did during this time period.

in Progress Pictures 27 upvotes 1 year ago

A user's 3-month progress report on their treatment of hair loss using a stack of finasteride, dutasteride, and minoxidil, with additional supplements, diet and workout routine, and before-and-after photos.

community 1 year Post HT 2200 Grafts + fin 8 Months Then switched to dut

in Progress Pictures 519 upvotes 2 years ago

A user who experienced positive results from using finasteride and dutasteride to treat their hair loss, with 2000 grafts being transplanted in the temples area for further improvement. They also discussed cost and other treatments such as minoxidil.

community Transient and Permanent Effects of Finasteride Use

in Research/Science 154 upvotes 3 years ago

Potential side effects of 5AR inhibitors like finasteride and dutasteride. Users debate risks, benefits, and personal experiences with these hair loss treatments.

community Hey guys I’m a Compounding Pharmacist specialized in Hair-loss who makes Topical Finasteride Foam +/- minoxidil

in Treatment 28 upvotes 3 years ago

A compounding pharmacist offers affordable topical finasteride foam with Anagain and micro-dose finasteride capsules for hair loss. They provide telehealth services across Canada and private appointments for international patients.

community Certified old, at 51, balding since 25, the resurrection!

in Progress Pictures 439 upvotes 1 month ago

A 51-year-old shared progress on hair regrowth using topical Minoxidil and Finasteride over four months, noting significant improvement and plans for future hair transplants. The user emphasized the benefits of modern treatments and societal changes in attitudes towards hair loss.

community I just went to a dermatologist and there were many red flags about him.

in Treatment 14 upvotes 1 year ago

A user visited a dermatologist for hair loss concerns and was prescribed a hair lotion called "Lotion revolotion evdermia," which is meant for hair toning, hydration, and anti-aging, not regrowth. The user found the dermatologist's behavior and the prescription to be questionable.

community Honestly have no idea but I’m trying to be hopeful lol

in Satire 143 upvotes 6 months ago

The conversation discusses hair loss and the emotional impact it has on individuals. Treatments mentioned include Minoxidil, finasteride, and RU58841.

community Oral Min & Fin - 9 Months no results - diffuse thinner

in Treatment 6 upvotes 8 months ago

A 21-year-old has been using 0.4mg finasteride and 1mg oral minoxidil (increased to 2mg) for 9 months with no noticeable hair growth and worsening hair condition. They are considering stopping finasteride due to side effects and are seeking advice on other treatments.

community I just want to say Ru58841 saved my life.

in Chat 28 upvotes 1 year ago

A user's experience with hair loss and scalp inflammation, which was alleviated by using RU58841 along with finasteride and dutasteride. A theory of inflammation possibly being a cause of hairloss is also discussed.