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      community New angles to attack beyond DHT

       4 upvotes 2 years ago
      Exploring hair loss treatments beyond DHT, including Minoxidil, pyruvate, Gt20029 targeting androgen receptors, and vasodilators. Other options like Kx826, adenosine signaling, growth factor topicals, and microneedling are also discussed.

      community Bicalutamide vs Finasteride for female AGA plus TE

       4 upvotes 6 months ago
      OP is considering Bicalutamide for female AGA and TE but is concerned about its side effects and effectiveness compared to Finasteride. OP is also using Minoxidil and Spironolactone but is experiencing significant shedding and is unsure if it's androgen-driven or due to Minoxidil changes.

      community Update progress on Fin, Min, and Kx-826

       8 upvotes 1 year ago
      The user is using oral finasteride, minoxidil, and KX-826 for hair regrowth, noticing small improvements. They plan to add ketoconazole shampoo and consider a hair transplant with verteporfin after a year of treatment.

      community Switched to DUT from Fin after 30 months of no progress

       161 upvotes 2 months ago
      The user switched from finasteride to dutasteride after 30 months with no progress, experiencing a significant shed initially. The current treatment includes daily dutasteride, oral minoxidil, topical finasteride and minoxidil, derma stamping, PRP, and calecim exosomes.

      community Progress and Contemplating H/T

       16 upvotes 3 weeks ago
      The user has been using oral finasteride and minoxidil since mid-April and sees progress on the crown but not the front, considering a hair transplant. Suggestions include continuing medication, adding microneedling, and possibly getting a hair transplant for areas with no hair.

      community I had GPT create a comparison of pp405 week 8 results vs Fin and Min

       1 upvotes 1 year ago
      PP405 shows significantly better early-stage hair regrowth results compared to minoxidil and finasteride, with 31% of users experiencing over 20% density increase in 4–8 weeks. Minoxidil and finasteride show minimal or no visible regrowth in the same timeframe.

      community PP405 - A True Breakthrough or Another Disappointment?

       34 upvotes 1 year ago
      PP405 shows potential for hair growth, with 31% of advanced balding men experiencing over 20% increase in hair density in 8 weeks. However, skepticism persists due to selective data presentation and lack of long-term results, with comparisons to treatments like minoxidil and finasteride.

      community PCOS Hair Loss: What’s Helped Me (and What Didn’t)

       11 upvotes 1 year ago
      OP shares their experience with PCOS-related hair loss, highlighting that addressing vitamin D and ferritin deficiencies, managing hormones with spironolactone, and using gentle hair care products helped improve their condition. They advise against relying on "miracle" hair oils and emphasize the importance of medical evaluation and a combined approach to treatment.

      community Who is the ideal target for PP405? Will it render hair trasplants obsolete?

       2 upvotes 5 months ago
      PP405 is being discussed as a potential treatment for hair loss, with uncertainty about its effectiveness compared to existing treatments like finasteride, dutasteride, and minoxidil. There is cautious optimism, but its impact on hair transplants remains unclear.

      community Your progress pics are measuring lighting more than hair

      in Technology  11 upvotes 1 month ago
      A dermatologist is developing a device to standardize hair progress photos for those using finasteride and minoxidil, aiming to provide consistent data on hair status. Users express skepticism about its practicality and cost, suggesting it might be more suitable for clinics than consumers.

      community Can I mix minoxidil with Alpecin Caffeine Liquid?

      2 years ago
      A user is considering mixing 5% topical minoxidil with Alpecin Caffeine Liquid to enhance its effect, while also using oral finasteride. They seek feedback on potential efficacy loss and downsides of this mixture.

      community We Need A Solution For The Inflammatory Response related To AGA

      in Research/Science  16 upvotes 2 years ago
      The conversation is about finding a solution for scalp inflammation related to AGA, with the user expressing frustration that Minoxidil and Finasteride do not address inflammation. The user has researched glucocorticoids and topical NSAIDs for reducing inflammation and seeks advice from specialists.

      community PP405: latest news. Really interesting

       29 upvotes 5 months ago
      The conversation discusses impressive results from a 28-day application of a hair loss treatment. Users compare it to their experiences with Minoxidil and Dutasteride, noting excitement over the new findings.

      community Does anyone have experience with topical dut?

       8 upvotes 4 years ago
      The user has been using minoxidil for hair loss and is considering trying a compounded topical treatment with 0.1% dutasteride, minoxidil, tretinoin, collagen, and silicon, as recommended by a trichologist. They learned that dutasteride might be more effective than finasteride and are seeking opinions on the use of topical dutasteride.

      community Any chemists want to manufacture PP405 / JXL069? (Steps inside)

       114 upvotes 1 year ago
      The conversation discusses the potential of PP405 as a hair loss treatment, with some users expressing skepticism and others hopeful about its development. There is also mention of other treatments like Minoxidil, Finasteride, and Pyrilutamide, with users debating the effectiveness and safety of self-experimentation versus waiting for clinical trial results.

      community Won’t pp405 and gt20029 be patented and be almost unreasonably expensive

       29 upvotes 1 year ago
      Concerns about the potential high cost of new hair loss treatments, pp405 and gt20029, were discussed, with some users willing to pay a premium if they are effective. Alternatives like finasteride and minoxidil are mentioned as current, more affordable options, and there is speculation about future generic versions and black market availability.

      community Combining Ru58841 with my Topical Formula

       3 upvotes 1 year ago
      A user is combining RU58841 with a topical formula containing finasteride, dutasteride, minoxidil, triamcinolone, caffeine, and other ingredients. They have just started using it and report no side effects so far.

      community Any good place to buy KX-826, AHK‑Cu and PTD-DBM?

       1 upvotes 5 months ago
      The conversation discusses purchasing experimental hair loss treatments KX-826, AHK-Cu, and PTD-DBM, with the user already using Minoxidil and having side effects from Finasteride. Concerns about the legitimacy of certain suppliers and the authenticity of products like pp405 are also mentioned.

      community Ordered PTD-DBM from tailor made

       6 upvotes 5 years ago
      The conversation discusses hair loss treatments, including finasteride, microneedling, minoxidil, and PTD-DBM. The user has not noticed significant regrowth and is considering cost-effective options like valproic acid.

      community What happened to Pyrilutamide?

      in Technology  1 upvotes 1 year ago
      Pyrilutamide's 0.5% solution showed minimal improvement, while the 1% solution appears more promising but costly. The user is currently using finasteride and oral minoxidil and considering adding Pyrilutamide if effective and affordable.

      community Rate my regimen: 20yo/M looking for advice

      in Satire  145 upvotes 4 years ago
      A 20 year old male discussing his hair loss regimen, which includes using topical dutasteride, rogaine, RU58841, minoxidil and Avodart pills as well as scalp massage, stabbing head with steak knife, counting shed hairs under a hair net and sending them to a lab for analysis. Suggestions from other users include scalping method and switching to saw palmetto and zinc supplements.