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      community What’s in Your 'Dream' Topical?

      in Treatment  6 upvotes 1 year ago
      The conversation discusses creating a personalized topical treatment for hair loss, with ingredients like finasteride, minoxidil, tretinoin, melatonin, caffeine, and others. Users share their ideal formulations, including combinations of minoxidil, finasteride, tretinoin, adenosine, and other compounds, while also discussing the importance of managing inflammation.

      community Thoughts on this product or other suggestions?

       12 upvotes 11 months ago
      The conversation discusses various hair loss treatments, including minoxidil, finasteride, latanoprost, tretinoin, dutasteride, and cetirizine, with concerns about effectiveness, cost, and potential side effects. Users express skepticism about the product's price and the combination of multiple compounds.

      community Surprisingly thorough study on He-Shou-Wu/Fo Ti

       13 upvotes 3 years ago
      He Shou Wu (Fo Ti) extract was found to prolong the hair growth phase, inhibit 5-alpha-reductase (like finasteride), reduce androgen receptors, and increase growth factors, potentially outperforming minoxidil in recovering hair follicle size after DHT exposure. Two compounds, emodin and TSG, are identified as responsible for these effects and warrant further investigation.

      community RU58841 vs. KX-826 vs. CB-03-01

       16 upvotes 3 months ago
      RU58841 shows the strongest results despite weaker binding affinity, while KX-826 and CB-03-01 are more expensive and have minimal side effects. RU58841 is considered effective but has potential health risks if ingested; users report positive outcomes with RU58841 and finasteride.

      community Is my topical Minoxidil solution optimal enough?

       1 upvotes 10 months ago
      The user is using a 5% minoxidil solution with low propylene glycol and 1 mg of oral finasteride daily but is still experiencing hair shedding, especially at the temples and front. They are concerned about absorption issues and considering adding tretinoin to improve results.

      community RU-58841 appears to not be soluble in common Minoxidil solutions

       7 upvotes 11 months ago
      RU-58841 does not dissolve well in common Minoxidil solutions due to water content, requiring a 70/30 ethanol/propylene glycol mix. Users report using separate solutions for RU-58841 and finasteride/Minoxidil for better results.

      community No access to RU, Pyri. Any alternative anti androgen?

      in Treatment  4 upvotes 1 year ago
      The conversation discusses alternatives to RU58841 for hair loss treatment, with suggestions including topical spironolactone, peppermint and rosemary oils, and saw palmetto. The user also considers ordering RU58841 from China but finds it too expensive.

      community Where can I find Minoxidil free multi-ingredient topicals?

       2 upvotes 3 weeks ago
      The conversation is about finding a topical hair loss treatment that includes finasteride or dutasteride but excludes minoxidil, with a preference for additional ingredients like retinol, hydrocortisone, or ketoconazole, and avoiding propylene glycol. The user is already using oral minoxidil and experienced side effects with oral finasteride.

      community What dosage topical Finasteride should I go with?

      1 year ago
      The conversation is about adjusting the dosage of topical Finasteride to avoid side effects like chest pain and breast swelling. The user is considering reducing the concentration to 0.1% or trying microdosing with 0.01-0.025% for lower systemic effects.

      community Anyone know cheapest/best way to source RU58841 for Aussies?

       2 upvotes 6 months ago
      The conversation is about sourcing RU58841 for hair loss treatment in Australia and discusses the lack of effective alternatives. Alternatives mentioned include Kx826, fluridil, cb, alfatradiol, and topical spiro, but they are considered weak compared to RU58841.

      community Studies or evidence for concentration for topicals?

      in Research/Science  1 upvotes 1 year ago
      The conversation discusses using different concentrations of topical treatments for hair loss, specifically Minoxidil, Finasteride, Dutasteride, and Tretinoin. The user is considering higher concentrations after previous treatments were ineffective.

      community isoflavones to combat gyno?

       4 upvotes 6 years ago
      Isoflavones from soybeans may help limit estrogen's effects on the body, potentially preventing gyno. However, surgery is the only way to remove gland enlargement.

      community Topical Dutasteride 0.05% With Trichosol In Europe

       5 upvotes 3 weeks ago
      A user from Ireland is seeking topical dutasteride with trichosol, which is unavailable in Ireland, and is looking for European pharmacies that can provide it. Recommendations include pharmacies in Switzerland, Italy, Belgium, and Bucharest, with mixed reviews about Farmacia Parati in Italy.

      community DNA Testing by Roots by Genetic Arts

       4 upvotes 2 years ago
      A user shared their positive experience with Roots by GA, a company that creates personalized hair loss treatments based on DNA analysis, which confirmed their inability to tolerate finasteride. The user is satisfied with their progress 30 days after a hair transplant and the customized formula they received.

      community Sublingual Minoxidil - Cure to Hairloss?

      in Minoxidil  583 upvotes 2 years ago
      The conversation discusses the potential benefits of sublingual minoxidil for hair loss treatment. It suggests that sublingual minoxidil, which bypasses the liver, may have fewer side effects, greater bioavailability, and could be more effective than oral minoxidil.

      community When is GT20029 going to come out?

       37 upvotes 2 years ago
      The conversation discusses the anticipation and skepticism around the release of GT20029 for hair loss treatment. The original poster has been using Finasteride and Minoxidil but is hopeful for GT20029, while others express doubts about its timely release and suggest alternatives like KX826 and hair transplants.

      community Experience with CB (Breezula)?

       4 upvotes 6 years ago
      CB 03 01 (Breezula) was tried for hair loss but showed no significant improvement, with issues in dissolving and application. Finasteride and dutasteride remain the most effective treatments, while minoxidil is also used; CB's effectiveness is questioned, and topical alternatives like bicalutamide are considered.

      community Is RU58841 making a comeback? Is it worth it?

       5 upvotes 1 week ago
      RU58841 is being reconsidered as a hair loss treatment, with some users reporting early positive signs, though concerns about potential heart issues exist. Alternatives like KX826 and traditional treatments like dutasteride and minoxidil are also discussed.

      community My 15+ Year Hair Loss Journey: DUPA, Recurrent Alopecia Areata, & different dosages of Min / Fin topicals - Advice needed on next steps.

       4 upvotes 1 week ago
      The user has been managing hair loss for over 15 years, using treatments like Minoxidil, Finasteride, and corticosteroids, while experiencing side effects and recurrent Alopecia Areata. They seek advice on progression and potential underlying conditions, questioning if their hair loss is due to an autoimmune issue beyond typical patterns.

      community Is this the 2026 Hairloss Nuclear Stack?

       30 upvotes 6 months ago
      A user discusses their extensive hair loss treatment regimen, which includes dutasteride, oral and topical minoxidil, RU58841, various supplements, and lifestyle changes. The conversation includes opinions on the effectiveness and necessity of such a comprehensive approach, with some users suggesting alternatives like microneedling and questioning the high dosage of dutasteride.

      community Hair Regrowth timeline (Oct. 2024 - Till now)

      in Progress Pictures  13 upvotes 1 year ago
      The user experienced hair regrowth using a routine of 5% minoxidil, 0.1% finasteride, 0.1% dutasteride, and 0.025% tretinoin, with plans to adjust the treatment. They noticed significant improvement within a year and are considering changes to avoid potential hair shedding.

      community Any men have any luck with topical spironolactone?

      in Treatment  2 upvotes 1 year ago
      The conversation discusses using topical spironolactone for hair loss, with the original poster already using oral and topical minoxidil, dutasteride, and latanoprost. Opinions differ on the effectiveness and safety of adding spironolactone, with some users suggesting alternative treatments like finasteride and vitamin supplements.