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SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

A user with diffuse thinning experienced no hair regrowth with finasteride or Avodart but slowed hair loss with Avodart. They are considering trying Minoxidil and are seeking advice on whether to use foam or liquid, and if combining it with other treatments could be beneficial, excluding micro-needling due to scalp irritation concerns.

The conversation is about seeking updates on new hair loss treatments, specifically mentioning scube3 and GT20029, with one person mentioning HMI_115 as showing promising results.

Hair cloning is being developed by companies like Kangstem Biotech and Stemson, with potential availability in a few years. Initial costs are expected to be high, but prices may decrease over time.

The conversation discusses the failure of Phase 3 trials for the hair loss treatment KX-826, with no significant difference found between the drug and placebo. Some users express disappointment and skepticism, while others discuss alternative treatments like Minoxidil, finasteride, and RU58841.

The user started a hair loss treatment with dutasteride, which initially stopped hair loss but later became less effective. They are considering combining finasteride with dutasteride and have also started taking vitamin D, biotics, and collagen, while others suggest trying finasteride, RU58841, minoxidil, and using a dermapen.

The conversation is about a user considering the use of Ketoconazole 2% shampoo before showing signs of male pattern baldness (MPB) to potentially delay its onset, inspired by a YouTuber who uses the shampoo to reduce scalp DHT levels. The user's interest in this preventative measure stems from a family history of MPB.

The post discusses a theory that hair regrowth after transplant is due to the angiogenesis process (new blood vessels forming), not because the transplanted hair is unaffected by DHT. The responses highlight the established belief in 'donor dominance' (the importance of the hair's origin in transplantation) and skepticism about the new theory.

RU58841 combined with finasteride or dutasteride is more effective than RU58841 alone for hair loss. Users suggest combining these with minoxidil and microneedling for better results.

User experienced hair loss after taking creatine with finasteride for 8 years. Others shared similar experiences, but some suggested it could be a minoxidil shed.

The efficacy of microneedling for hair regrowth as either a stand-alone therapy or adjunct to Minoxidil, and whether Tretinoin is a safer and more effective option. Replies include personal accounts from users who have had success with microneedling in combination with minoxidil and peptide serums, as well as considerations of technique, depth, and potential scarring.

Hair cloning might be available in 10-15 years, but current and upcoming treatments like finasteride, dutasteride, and new drugs like g20029 may make it unnecessary. Advances in hair regrowth technology and treatments are expected to be more cost-effective and accessible.

The user experienced worsening hair loss after starting oral minoxidil and using creatine, with no improvement after six months. Many suggest stopping creatine, as it may increase DHT and contribute to hair loss, and consider using topical minoxidil or other treatments.

Topical finasteride is discussed as an alternative to oral finasteride, with some users experiencing fewer side effects and positive results. RU58841 and minoxidil are also mentioned as effective treatments for hair loss.

The post discusses diluting 100ml of 0.1% topical finasteride with 90ml of stemoxydine to create a 0.05% solution, aiming for a longer-lasting and potentially less side-effect-prone treatment. The user seeks feedback on this idea.

The user claims to have successfully treated hair loss using natural supplements like collagen, L-lysine, zinc, B12, and bamboo shoot extract, without using the "Big 3" treatments (Minoxidil, finasteride, RU58841). The community is skeptical, demanding proof and emphasizing that the "Big 3" are proven effective, while natural remedies are often not.

A user reported increased shedding and some side effects like ball ache and potential watery semen after taking 0.25mg of finasteride daily for two months, but noted a high sex drive and considered the shedding a possible sign of new hair growth. Other users discussed dosage differences, with some suggesting starting with a smaller dose and monitoring effects, while others shared their experiences with no shedding or hair growth yet.

The user initially used minoxidil for hair loss, stopped, and then tried redensyl, but is unsure if it works effectively alone. They are considering finasteride despite concerns about side effects and are also using natural treatments like Babushka Agafia shampoo and pomelo peel concoctions.

The conversation discusses the difficulty in distinguishing between side effects of finasteride (like brain fog and loss of libido) and depression caused by hair loss. Users share experiences of severe depression while on finasteride, leading some to stop the treatment despite anxiety over hair loss.

A 22-year-old experienced significant hair loss due to high stress, SSRI side effects, and Androgenic Alopecia, and has seen some regrowth after starting finasteride and using ketoconazole shampoo. They are inquiring if continued use of finasteride and stress reduction alone can lead to further hair regrowth.

A user thanks the group for sharing experiences, leading them to start finasteride, dermarolling, and castor oil, while using Nizoral and LLLT. They plan to reintroduce minoxidil later.

A user shared their positive experience with hair regrowth using finasteride and minoxidil, noting improvements in hair thickness and confidence. They also mentioned using a dermaroller and managing side effects, while others in the conversation shared similar experiences and advice on hair loss treatments.

Microneedling combined with Minoxidilmax Essengen 6 (minoxidil and finasteride) and Nizoral shampoo led to impressive hair regrowth. The user achieved significant results without oral finasteride, using a Dr. Pen A7 for microneedling.

Hair loss treatments discussed include Minoxidil, Finasteride, and RU58841. User HanSolo100 asks if hair quality can improve in the second year of Finasteride use, sharing their experience with no noticeable difference in hairline but having long, wispy hairs.

The user experienced good results with a topical blend of finasteride and minoxidil, along with dermarolling, after stopping oral finasteride due to side effects. However, they faced significant shedding when transitioning from oral to topical treatment.

The conversation discusses the impact of finasteride on sperm, including potential side effects like decreased ejaculate volume and total sperm count. Users share experiences and concerns about fertility tests before and after starting finasteride.

Castor oil may help hair growth by targeting specific receptors and reducing certain scalp levels, with some users reporting thicker hair. Peppermint oil is suggested as an alternative to minoxidil, while opinions on the effectiveness of plant-based treatments for hair loss vary.

A user shared their experience with finasteride, reporting severe side effects like erectile dysfunction and watery semen, which improved after stopping the medication. They emphasized the risks of finasteride and decided not to resume its use despite hair loss stabilization.

Minoxidil and finasteride are the main treatments for hair loss, with Breezula and hair cloning being explored. No definitive cure is available yet.

A person in their early 30s is experiencing increased hair shedding after stopping birth control and reducing spironolactone, which they've been on for years. They are concerned about the hair loss, which is different from their usual hereditary pattern, and are seeking advice.