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This post and conversation are about the molecular mechanisms triggered by microneedling, specifically its effects on inflammation, tissue remodeling, epithelial proliferation, differentiation, and collagen synthesis. The discussion highlights the potential benefits of microneedling for hair loss treatment.

A user shared their positive experience with a hair transplant at Wimpole Clinic, performed by Dr. Malkani, and discussed using finasteride at a reduced dose due to side effects. They also mentioned avoiding minoxidil due to heart pain and taking supplements like biotin, marine collagen, viviscal, and krill oil.

The user experienced no results for 3.5 years while using finasteride, minoxidil, and microneedling, but saw improvement after increasing Dutasteride to 0.6mg daily. Current routine includes Dutasteride 0.6mg, minoxidil once a day, and supplements like collagen, biotin, and vitamin D.

The conversation discusses a hair loss treatment regimen that includes scalp massage, derma rolling, saw palmetto, rosemary, peppermint oil, pumpkin seed oil, and various supplements like vitamins C and D, multivitamins, biotin, collagen, and fish oil. The user is asking if the treatment has led to hair regrowth.

A user shared an 8-month hair regrowth progress using finasteride, topical minoxidil, and microneedling, and others reacted positively, asking for details about the treatment regimen. The user also mentioned taking cod liver oil and a hair multivitamin with biotin and collagen.

The user's experience with oral minoxidil, which resulted in under-eye wrinkles; other users sharing their experiences and advice regarding hair loss treatments such as topical minoxidil, finasteride, RU58841, and collagen supplementation.

The conversation is about a person's hair loss treatment routine, which includes Metformin, sleep in darkness, avoiding EMF at night, Nizoral, Dermarolling, Castor oil, and Collagen. They have observed less hair shedding and increased hair volume.

The user has been using Minoxidil and Finasteride since late 2019 with good results but is experiencing a dry, flaky scalp and shedding hairs. They also use Nizoral, biotin, zinc, magnesium, and collagen supplements, and their dermatologist prescribed fluocinolone acetonide to reduce flaking.

A user shared their aggressive hair loss treatment regimen, which includes daily use of Avodart (dutasteride) and Minoxidil, bi-weekly use of Davines Purifying shampoo, and almost daily use of Ducray Anaphase+ shampoo, along with supplements like vitamin D3, collagen, biotin, and zinc. They also use a dermastamp every 10 days and are considering a hair transplant for increased density, followed by a switch to finasteride and Minoxidil foam.

A user noticed wrinkling under one eye, possibly due to Minoxidil use. They seek advice on preventing or fixing this issue.

The conversation is about finding a conditioner suitable for thinning hair, with the original poster currently alternating between a caffeine shampoo and Nizoral every two days but not using any conditioner.

The conversation provides tips to reduce facial skin side effects from Minoxidil, such as changing pillowcases, sleeping on the back, careful application, hydration, and taking breaks. One reply suggests that alcohol in Minoxidil formulations, not Minoxidil itself, may cause skin aging.

The conversation discusses a user's six-month progress in treating hereditary hair loss using a regimen that includes minoxidil, finasteride, dutasteride, and other medications. Opinions vary on the effectiveness and logic of the treatment, with some users suggesting additional methods like microneedling.

The user is experiencing hair loss and is using oral finasteride, considering adding RU58841 and microneedling, and planning a hair transplant. They are seeking advice on whether to wait for treatment results or proceed with the transplant.

The user is considering using Tacrolimus Solution and topical Dutasteride to avoid shedding caused by Minoxidil, which they fear may lead to facial side effects. They are also concerned about scalp sensitivity and are exploring different treatment bases to manage seborrheic dermatitis.

Topical 2-deoxy-D-ribose (2dDR) regrows hair in mice almost as well as 2% Minoxidil. However, 2dDR may contribute to oxidative stress and hair loss due to the formation of advanced glycation end products (AGEs).

The new OGX thick and full shampoo formula makes hair poofy and soft, ruining its previous thickening effect. The user is seeking old bottles of the original formula.

Ketoconazole is no longer sold in the UK, and pharmacies have replaced it with non-ketoconazole options. Users are discussing its availability and possible alternatives.

The user has been using 5mg oral Minoxidil daily and started with 1mg Finasteride daily, but reduced the dose due to side effects and is considering trying RU58841. They are concerned about thinning hair despite some temple recovery and are seeking advice on maximizing progress.

A user shared progress pictures showing improvement in PCOS-related hair loss after six months of using topical minoxidil, dermarolling 0.5mm weekly, and taking biotin gummies. They expressed happiness about the appearance of new baby hairs.

A 37-year-old man shared his 1.5-year progress using finasteride and supplements for hair loss, planning a hair transplant for further restoration. Commenters noticed significant improvement in hair quality and density from his treatment.

The user is seeking recommendations for the best shampoo and conditioner for hair loss, excluding ketoconazole, and is currently taking finasteride 1mg. They are also curious if hair products can still be used alongside hair loss treatments.

The use of tropoelastin injections and verteporfin for hair transplant recipients to help regrow donor area hairs, as well as research done on tropoelastin injections restoring elastin in scarred heart tissue and skin. There are discussions about why it is taking so long to get cosmetic mass produced tropoelastin injectables on the market.

Nutrafol, a hair loss supplement, has limited and potentially biased research, with one study showing a 10% increase in hair count for women after 6 months but no significant results for men. The user concludes that cheaper, well-studied options like minoxidil may be more effective, especially for men, given the lack of evidence supporting Nutrafol.

Blocking DHT may slow down aging and improve skin, with users reporting positive effects from finasteride. Minoxidil and RU58841 are also mentioned as treatments.

Late 20s woman struggles with worsening hair loss and tried various treatments without success. Now trying spironolactone and ketokonazole shampoo, hoping for improvement.

The user's hair regrowth plan includes topical treatments (RU58841, azelaic acid, ketoconazole), oral supplements (Gia Herbs, castor oil), microneedling, PTD-DBM peptide with valproic acid, red light therapy, inversion table with scalp massage, and platelet-rich fibrin injections. Commenters suggest that finasteride and minoxidil are essential treatments for male pattern hair loss, which are missing from the plan.

The conversation is about a user's comprehensive hair loss treatment plan, including finasteride, minoxidil, dermaroller, Nizoral shampoo, vitamin D, biotin, and zinc. The user describes their approach as a strategic battle against DHT, with finasteride as the main treatment.

Using a combination of micro-needling and exosome injections as a potential treatment for male pattern baldness, which could result in 50% or more regrowth.

A user experienced hair thinning and scalp issues after using a sebum-regulating shampoo and perm treatments. They are advised to consider potential allergies, try a simple shampoo, and research treatments like finasteride for possible male pattern baldness.