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Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

The user shared their 5-year hair loss journey, initially using a product called Triphasic Progressive by Rene Furterer, which gave good results. Later, they switched to FDA-approved medications finasteride and minoxidil, which also helped, but they noticed the most significant progress with Triphasic. They're considering trying it again if minoxidil doesn't show improvements.

Tretinoin's effectiveness for hair regrowth alone is questioned, with interest in its use with oral minoxidil. The discussion also considers whether finasteride or dutasteride is the better DHT blocker and if switching to dutasteride is advisable for those without side effects from finasteride.

The discussion is about a hair loss drug called pyrilutamide. Users discuss its efficacy, safety, and expected market release around 2025-2026, with some expressing concerns about the authenticity of current market offerings.

The user experienced concerning side effects like throat irritation, shortness of breath, chest pain, and testicle pain after using RU58841 for hair loss, despite also using finasteride and minoxidil. Other users shared mixed experiences, with one advising to stop using RU58841 due to similar side effects, while another reported significant hair loss reduction without side effects.

A user is testing clascoterone (Winlevi) on their scalp for hair loss and has noticed a reduction in scalp sebum after one month. They are also using other unspecified treatments and plan to provide an update after the second month.

The user "jsonparquet" shared their 11-month progress using a combination of finasteride, minoxidil, microneedling, and Nizoral for hair loss. Other users expressed amazement and suggested waiting another year before considering a hair transplant. One user shared their own experience of slow but steady gains over 3 years using a regimen of topical finasteride and minoxidil.

A 35-year-old has seen no hair regrowth after 9 months using treatments including finasteride, pyrilutamide, microneedling, ketoconazole shampoo, and topical dutasteride, but experienced side effects with RU58841. Commenters suggest starting minoxidil for better results and question why it wasn't included from the beginning.

Microneedling for hair loss and its potential long-term effects. Some users believe it can cause fibrosis and scar tissue if done too frequently or deeply, while others claim it has improved their hair loss when done correctly. There is limited scientific research on the topic.

The review discusses traditional hair loss treatments like minoxidil and finasteride, and newer options like Low-Level Laser Therapy, microneedling, and platelet-rich plasma for androgenetic alopecia. It highlights the need for more high-quality trials to assess these treatments' effectiveness and standardized protocols for emerging therapies.

The post and conversation are about a user's positive progress with hair loss using minoxidil and finasteride. No noticeable side effects were reported.

The conversation discusses why DHT (dihydrotestosterone) negatively affects scalp hair but promotes growth elsewhere on the body. Various opinions include genetic predispositions, differences in hair follicle reactions to DHT, and the potential role of Omega-3 in reducing inflammation and promoting hair health.

The user is asking for opinions on whether their hair growth is due to Pantostin and hormone treatments. One commenter confirms regrowth and asks about the hormone treatments.

A 37-year-old man treated his hair loss with 0.5mg finasteride every other day and 5% minoxidil twice daily for 5 months, reducing finasteride from 1mg due to side effects. His hair improved significantly, with positive changes visible from all angles, and he experienced no more side effects after the dosage adjustment.

A user named "paulsac11" shares their success story of treating hair loss. They started with topical minoxidil, then switched to oral minoxidil and dutasteride. They also used a shampoo and conditioner from Keeps. After eight months of treatment, they have seen significant improvement in their hairline.

A user shared a six-month update on hair improvement using Pyrilutamide and Minoxidil, noting significant hair regrowth and strength. Some participants questioned the legitimacy of the results and the source of Pyrilutamide.

User asks if Kintor, HMI-115, or Olix will release hair loss drugs in 2023. Conversation discusses potential treatments and release dates.

Dutasteride might be better for hairline due to varying levels of 5AR activity in scalps. Genetic tests can determine if finasteride is enough or if dutasteride is needed.

A man in his 50s, who has been on Finasteride for 15 years, is considering adding a custom topical Minoxidil blend to his treatment due to recent hairline recession. He questions whether the custom blend is more effective than generic Minoxidil, expresses concerns about shedding and body hair growth, and seeks advice on application timing with styling products and whether to pursue other treatments like PRP or laser.

Follicum discovered that their drug FOL-005 increased hair count by 12 hairs per cm2 in patients with less than 255 hairs per cm2 and is planning a phase 2b trial. They are currently fundraising for the trial, and the drug may also be effective for women.

User shares obsession with bald heads and thanks others for update pics. Another user mentions taking Finasteride despite potential side effects.

New product Tomorrowlabs HSF targets hair loss through HIF pathway indirectly by removing scalp iron. Minoxidil and Stemoxydine also relate to HIF pathway.

Teenager with hair loss shares experience and encourages others to address their hair loss early. They use a stack of topical finasteride/minoxidil, derma stamp, and ketoconazole shampoo for treatment.

Users discuss waiting for new hair loss treatments and share struggles with side effects from current options like Minoxidil and Finasteride. They express hope for Pyrilutamide and CosmeRNA to provide better solutions.

The efficacy of taking 1mg finasteride three times a week instead of daily for hair loss, with some users arguing that it is just as effective because finasteride has a long half-life in the scalp tissue and lower doses have been shown to be effective. Other users suggest experimenting with various treatments such as minoxidil and finasteride to achieve best results.

Treatments for hair loss, specifically the use of minoxidil, finasteride and RU58841. Replies to this post suggest that users should share relevant information publicly rather than through direct messages.

Switching from finasteride to dutasteride as a treatment for hair loss, with advice given that titrating up to daily use is optimal and results may be seen after one year. Additionally, the user mentioned adding topical minoxidil 5% which has produced good results.

Phase II for TDM-105795 for Androgenic Alopecia is set to begin in April 2023. The study aims to evaluate the efficacy and safety of TDM-105795 in male subjects.

GT20029 and CosmeRNA are both potential hair loss treatments; GT20029 breaks down the androgen receptor, while CosmeRNA prevents its production. Continuous use is needed, but less frequently than current treatments like Minoxidil and Finasteride.

A user is using minoxidil for hair loss and considering adding finasteride but their dermatologist advised waiting to see if minoxidil works alone. They are thinking about taking saw palmetto (serenoa repens) and biotin as alternatives and are asking for others' experiences and potential side effects.