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      community Expectations control for SCUBE3

      in Research/Science  21 upvotes 8 months ago
      SCUBE3, a protein linked to hair growth in moles, was discovered over 25 years ago and is being developed by Amplifica for potential hair loss treatment. Concerns exist about SCUBE3's association with cancer, as it is a protein that promotes cell growth, which could potentially trigger cancer development if used for hair growth therapy.

      community 28 Days on Oral Min and Vitamins Only

      in Is this regrowth?  132 upvotes 8 months ago
      The user is taking 2.5mg of oral Minoxidil and using Rosemary and Peppermint oil for hair regrowth, with no side effects reported. They are considering increasing the dosage to 5mg after three months and have been advised to include a dermaroller in their routine.

      community Rare Non responder to Finasteride, Dutasteride, and oral minoxidil

      in Minoxidil  78 upvotes 8 months ago
      A user did not respond to finasteride, dutasteride, and oral minoxidil for hair loss after four years of treatment and is considering scalp micropigmentation (SMP). Other users suggest the hair loss pattern may indicate alopecia areata and recommend seeing a dermatologist.

      community Does microneedling damage scalp?

      in Research/Science  12 upvotes 9 months ago
      Microneedling does not prevent future hair transplants, but some surgeons report the skin becomes "harder" in treated areas. There is no clear evidence to confirm this effect.

      community Better then Minoxidil( at least for me and my family)

      in Treatment  42 upvotes 9 months ago
      Capronium Chloride and Trichoxidil are suggested as better alternatives to Minoxidil for hair growth without heart side effects. The Japanese Dermatological Association recommends topical Minoxidil over Capronium Chloride.

      community Fats on your Head to Stop Hair Loss?

      in Research/Science  141 upvotes 9 months ago
      The conversation discusses the potential of long-chain unsaturated fatty acids, like oleic and linoleic acid, as an additional treatment for hair loss, which may inhibit the enzyme responsible for converting testosterone to DHT and promote hair growth. Users humorously suggest using oils topically and discuss other hair loss treatments, but the main focus is on the science behind fatty acids and their role in hair health.

      community Hope Medicine HMI-115 got 28M$ investment

      in Research/Science  58 upvotes 9 months ago
      Hope Medicine received a $28M investment for HMI-115, a monoclonal antibody in phase II trials for treating androgenetic alopecia. Some users are skeptical about its effectiveness, while others find the investment and trial results encouraging.

      community Approximation of Scalp DHT Suppression Between 0.05 mg to 2.5 mg

      in Research/Science  63 upvotes 9 months ago
      The conversation discusses the effectiveness of various doses of Dutasteride in reducing scalp DHT and its impact on hair count. Users shared personal experiences with hair loss treatments, including Dutasteride, Finasteride, and Minoxidil, with one reporting significant hair loss reduction using a combination of oral Dutasteride and topical Minoxidil and Finasteride.

      community My barber noticed my progress 😁

      in Update  208 upvotes 10 months ago
      A user's barber noticed significant improvement in their hair thickness after they started using 2.5mg Minoxidil since August 2023 and 1mg Finasteride daily since September 2023. The user has experienced some headaches when missing Minoxidil doses but has not noticed major side effects.

      community A rant about hair loss misinformation on social media

      in Chat  43 upvotes 10 months ago
      Social media spreads misinformation about hair loss, often promoting unproven treatments like diet changes. Effective treatments like Minoxidil, finasteride, and RU58841 are overlooked.

      community Finasteride, minoxidil and pyrilutamide

      in Progress Pictures  79 upvotes 10 months ago
      The user tried minoxidil 5% for 3 years with little improvement, then switched to a 15% minoxidil with 0.1% finasteride solution once daily and started using pyrilutamide, resulting in significant hair regrowth over time. They are considering a hair transplant but are continuing with topical treatments to maximize hair growth first.

      community 1.5 years fin plus almost 3 years min, I think I’ve definitely made progress but I’m still not where I want to be, advice?

      in Progress Pictures  130 upvotes 10 months ago
      The user has been using finasteride for 1.5 years and minoxidil for almost 3 years for hair loss, and has seen some maintenance of hair but not significant regrowth. Suggestions from others include switching to dutasteride, trying oral minoxidil, and considering microneedling or hair fibers for better appearance.

      community Rosemary oil's potency as a dht blocker

      in Research/Science  65 upvotes 11 months ago
      Rosemary extract showed high inhibitory activity against DHT, similar to finasteride and dutasteride, but the conversation includes skepticism about its effectiveness in humans since the study was done on mice and rosemary oil is often considered ineffective based on personal experiences. Some suggest trying rosemary oil alongside other treatments, while others emphasize the difference between the extract used in the study and the oil.

      community Here are the results from my journey! I used saw palmetto tablets instead of Finasteride(I was afraid of using it), 5% Minoxidil spray and Derma Pen once a week 1.5mm.

      in Progress Pictures  306 upvotes 11 months ago
      The user shared their positive hair regrowth experience using saw palmetto tablets, 5% minoxidil spray, and a Derma Pen. The conversation debates the effectiveness of saw palmetto versus finasteride, with some advocating for natural treatments and others emphasizing the proven results of finasteride and minoxidil, often in combination with microneedling.

      community Phase 3 of pyrilutamide (kx-836) analysis of the efficacy

      in Research/Science  11 upvotes 11 months ago
      The conversation discusses the less impressive results of Pyrilutamide (kx-836) in phase 3 compared to phase 2, with a suggestion that a longer study might show more significant results. One user reports personal success with Pyrilutamide, experiencing no further hair loss and gradual regrowth.

      community RESULTS. Stick to the plan Fellas this is all about consistency

      in Progress Pictures  1462 upvotes 11 months ago
      A user shared their hair regrowth progress, attributing success to a consistent routine using finasteride, hair growth oil, Hims shampoo, a derma roller, and 5000 mcg biotin pills. They emphasized the importance of representation for people with similar hair types and encouraged others to stick with their treatment plans.

      community KX-826 Phase 3 Failed. Sorry guys...

      in Research/Science  49 upvotes 11 months ago
      The conversation discusses the failure of Phase 3 trials for the hair loss treatment KX-826, with no significant difference found between the drug and placebo. Some users express disappointment and skepticism, while others discuss alternative treatments like Minoxidil, finasteride, and RU58841.

      community Vertoporfin research update by Dr Bloxham

      in Research/Science  73 upvotes 1 year ago
      The conversation discusses the potential of verteporfin in treating hair loss, with some users reporting positive results and speculating that it could lead to a cure for baldness. Others are skeptical, and there's a debate on the effectiveness of verteporfin for regrowing hair and reducing transplant scars.

      community How You Can Help Speed Up the Verteporfin Trials

      in Research/Science  185 upvotes 1 year ago
      The post discusses speeding up verteporfin trials for hair loss treatment. The original poster, involved in the trials, requests help in crowdsourcing doctor emails to spread awareness and gather more support for the trials.

      community New Dutasteride Long Term Study (5 years) it works.

      in Finasteride/Dutasteride  106 upvotes 1 year ago
      The conversation discusses a five-year study on dutasteride, a medication for male hair loss. The study found that 89.9% of patients saw improvement or prevention of hair loss progression, with varying success rates based on different balding patterns. Side effects were mostly sexual and decreased over time. Dutasteride was concluded to be a long-term, safe, and effective treatment for male hair loss.

      community [Serious] Experience with grey-market KX-826 (Pyrilutamide)

      in Research/Science  2 upvotes 1 year ago
      The user experienced reduced hair loss using grey-market KX-826 alongside Minoxidil foam, achieving better results with Minoxidil liquid but restricted to foam due to an allergy. Initial side effects included shortness of breath, racing heart, and dizziness, which subsided after the first week.