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      community The pessimism about the Crisp Cas 9 is excessive

       12 upvotes 11 months ago
      CRISPR Cas9 could potentially treat baldness by targeting specific genes in hair follicles without affecting other body functions. There is optimism about its future use, despite ethical concerns and the current reliance on treatments like minoxidil and finasteride.

      community Best available SARD right now?

      in Treatment  3 upvotes 4 months ago
      The user is considering RU58841 and has been using dutasteride since age 17. They are seeking affordable SARD options, mentioning ASC-J9, GT20029, and AH001.

      community RU55481

       5 upvotes 12 years ago
      The conversation discusses using RU58841, a research chemical, for hair loss treatment. The user plans to use it due to side effects from finasteride and minoxidil, despite skepticism about its effectiveness and lack of FDA approval.

      community Is adding RCP(redensyl, capixyl, procapil) over min+fin make sense?

       5 upvotes 1 year ago
      The conversation discusses the effectiveness of adding RCP (redensyl, capixyl, procapil) to a hair loss treatment regimen that includes minoxidil and finasteride. Users share experiences, suggesting RCP may not be as effective as minoxidil, but could be useful for creating topical solutions.

      community PP405 (Non) Update - Feb 2025

       36 upvotes 1 year ago
      The conversation discusses the delay in the PP405 Phase 2 study results, now expected by the end of 2025, and skepticism about research practices. There is also mention of optimism for Amplifica's AMP303 and a topical treatment in early testing.

      community How safe and/or difficult would it theoretically be to turn raw 99.9% clascoterone into topical formula?

       6 upvotes 9 months ago
      The user discusses their hair regrowth success with minoxidil, red light therapy, massage, and derma stamping but expresses concerns about using finasteride due to potential side effects. They are interested in using clascoterone as a topical treatment for hair loss and are exploring the possibility of creating a topical formula from raw clascoterone powder.

      community Just started ru58841, ask me anything.

      in Research/Science  14 upvotes 8 months ago
      The conversation discusses a hair loss treatment regimen including oral dutasteride, oral minoxidil, tadalafil, and the recent addition of RU58841. The user shares experiences with these treatments, noting significant hair regrowth and stabilization, and discusses the cost and preparation of RU58841.

      community Chat is this real? Compound called clascoterone

       581 upvotes 9 months ago
      Clascoterone shows promising results for hair regrowth in men with androgenetic alopecia, with potential FDA approval by 2026. It acts as a topical androgen receptor blocker, offering a new treatment option with minimal side effects compared to existing treatments like finasteride.

      community New cure? A new combo to dream with hair regeneration

       33 upvotes 1 year ago
      A stem cell and adenosine triphosphate cocktail showed promising results in hair regrowth for male and female mice, with potential for future clinical trials. Users humorously reacted to the success in mice, expressing hope for human application.

      community Pp405 trials question - 2a/2b,

       6 upvotes 10 months ago
      PP405 trials have completed phase 2a, showing promising results with a 31% stat for hair density increase, and are moving directly to phase 3. Detailed results will be presented at a medical conference in 2026.

      community Anyone try RU58841 from this brand? truth진실

       4 upvotes 1 year ago
      The conversation discusses skepticism about the effectiveness and formulation of a $10 RU58841 gel from a Korean brand, questioning if ethanol is used to hold the active compounds. Concerns are raised about the feasibility of selling it at such a low price.

      community waiting for hope DIY pp405 guy that will save us😡😡😔

      in Satire  38 upvotes 10 months ago
      People are discussing the potential of a new hair loss treatment, pp405, and its approval timeline, comparing it to existing treatments like Minoxidil and finasteride. There is skepticism about its effectiveness and concerns about the time it will take for approval and availability, especially in Europe.

      community So I hacked the AAD 2026 live stream

       42 upvotes 5 months ago
      The conversation discusses a live stream presentation on Pelage PP405 for hair regrowth, with skepticism about its effectiveness compared to minoxidil. Some users express doubt and suggest sticking to proven treatments like minoxidil, finasteride, and RU58841.

      community The cure we've been ignoring: Anal Dutasteride

       225 upvotes 4 months ago
      The conversation humorously discusses using anal administration of Dutasteride as a novel method for treating hair loss, suggesting it could target DHT production more effectively. It includes satirical comments about the method's potential effects and absurd outcomes.

      community Progress pics of using KX-826 .9% (pyrilutamide) for one year

       19 upvotes 1 year ago
      The user experienced significant hair regrowth using KX-826 (pyrilutamide) 0.9% over one year, despite initial shedding phases. They reported no side effects and have stabilized hair loss with consistent use.

      community Anyone in the discord server for pp405 research?

      in Chat  5 upvotes 1 year ago
      The conversation is about users trying to regain access to a Discord server related to pp405 research, with differing opinions on the effectiveness of pp405 for hair loss. Specific treatments like Minoxidil, finasteride, and RU58841 are not mentioned in the conversation.

      community Results: 11mo using a 272 diode red light hat

       1 upvotes 7 months ago
      A user shared their 11-month experience using a 272 diode red light hat for hair loss, noting decent results despite inconsistent use and no medication. Another user suggested that real treatment like minoxidil or finasteride is necessary for long-term hair maintenance.

      community PELAGE PHASE 2 TRIALS FOR PP405 - Volunteers Needed

       24 upvotes 2 years ago
      PP405 is a topical gel being tested for hair regrowth in adults with androgenetic alopecia. Volunteers aged 18-55 are needed for a 16-week trial in several US locations.

      community GT20029 Will Replace Finasteride For Hair Loss

       58 upvotes 3 months ago
      GT20029 shows promise as a topical treatment for hair loss, potentially replacing finasteride for some due to its low systemic exposure and ability to degrade androgen receptors. However, skepticism remains about its long-term efficacy and availability, with some users expressing doubt about new treatments consistently failing to reach the market.

      community PP405 bandwagon, time to resume the hype train.

       164 upvotes 1 year ago
      PP405 shows promise in hair regrowth, potentially outperforming existing treatments like finasteride and minoxidil, with significant results in just four weeks. The treatment is still in early stages, with further trials needed to determine its long-term effectiveness and optimal dosage.

      community Counter-update: Cbum's transplant DOESNT look super good now

       223 upvotes 1 year ago
      Cbum's hair transplant is criticized for looking unnatural and not blending well, with some suggesting better results were expected given his resources. Discussions also cover the effects of steroids and finasteride on hair loss and muscle growth.

      community Dr. Rassman vs Kevin Mann on Eucapil

       4 upvotes 5 years ago
      Eucapil is discussed as a potential hair loss treatment with some believing it to be effective, though its efficacy compared to finasteride is debated. It is considered an anti-androgen treatment, often used alongside other treatments like minoxidil and finasteride, but lacks independent studies to fully support its effectiveness.

      community Now That PP405 Hype is Gone What is Everyone Coping with as the Next Cure?

       41 upvotes 1 month ago
      People are discussing various hair loss treatments, including finasteride, minoxidil, RU58841, and new potential treatments like vdphl01, ABS-201, and KX-826. Some express hope in future developments like hair cloning and CRISPR, while others emphasize acceptance and sticking with current treatments.