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      community PP405 2a study was a safety study. Some rational explaining.

       22 upvotes 1 year ago
      The conversation discusses the safety study of PP405, emphasizing that early trials focus on safety rather than efficacy, and that any efficacy data from such a short study should be viewed skeptically. It also highlights that the information released is primarily for securing funding, and that meaningful efficacy results are expected in later phases.

      community Ethanol left in sun, can I still use?

       5 upvotes 4 years ago
      Ethanol left in the sun is still usable as a vehicle for compounds like CB, as no chemical changes occur at 84°F.

      community Growth Update on Crown - Fin & Min

      in Progress Pictures  162 upvotes 1 year ago
      The user shared progress pictures of their hair growth after using finasteride, oral minoxidil, and undergoing a hair transplant with 4,200 grafts in Istanbul. They reported thicker hair and noticeable crown regrowth, with no side effects from the treatments.

      community Another blow to the cursed baldness

      in Research/Science  91 upvotes 11 months ago
      A South Korean company, Therazyne, has developed a promising hair loss treatment using a WNT chain surrogate that binds to Frizzled 7, with human follicle testing expected soon. Current treatments like minoxidil and finasteride are not seen as cures, and while optimism exists for future solutions like PP405, approval processes are lengthy.

      community Minimizing systemic DHT reduction with topicals

       5 upvotes 4 weeks ago
      The conversation discusses minimizing systemic DHT reduction using topical treatments for hair loss, specifically mentioning Minoxidil, Finasteride, and a proprietary carrier for DUT by XYON Health. The focus is on finding effective DHT blockers with minimal systemic absorption.

      community What are the upcoming or promising future developments in hair loss?

       31 upvotes 2 years ago
      The conversation discusses potential future hair loss treatments, including SCUBE3, hair follicle cloning, and GT20029, with mentions of past disappointments like CosmeRNA and hopes for treatments like Verteporfin for infinite donor hair.

      community I’m convinced that smile is aimed straight at bald people

      in Satire  131 upvotes 4 months ago
      The conversation humorously discusses hair loss, focusing on the envy of an older man, Massimo Cacciari, who has a full head of hair. Treatments mentioned include finasteride, minoxidil, RU58841, and hair transplants, with some users expressing dissatisfaction with baldness and considering various solutions.

      community Back from the dead. Fin/min/biotin. 8 month difference

      in Update  154 upvotes 10 months ago
      The conversation is about hair loss treatments, specifically using finasteride, minoxidil, and biotin, with a focus on the effectiveness of Hims products. Users discuss the results, potential side effects, and the role of biotin in the treatment.

      community a new supplement just released

       12 upvotes 8 years ago
      A dermatologist recommended a new supplement containing annurca apple, which reportedly doubles hair density and increases keratin after 60 days, to be used with finasteride. Some users are skeptical, considering it potentially ineffective or a marketing ploy, while others are open to trying it if it proves effective and affordable.

      community I took Finasteride 1mg for a month and now I can communicate with sea-mammals

       583 upvotes 8 months ago
      Finasteride is humorously claimed to enable communication with sea mammals, with users sharing exaggerated side effects and alternative hair loss treatments like olive oil and onion. The conversation is satirical, with users joking about unusual experiences and results.

      community Why is everyone still arguing about PP405 when clascoterone is already heading toward regulatory submission?

       46 upvotes 1 month ago
      Clascoterone is nearing regulatory submission as a potential new treatment for androgenetic alopecia, with positive Phase III results, while discussions continue about other treatments like PP405, minoxidil, and finasteride. Some users express excitement for clascoterone and Breezula, despite concerns about the effectiveness and practicality of topical treatments.

      community Is this solution unnecessarily aggresive?

      in Product  2 upvotes 8 months ago
      The solution contains minoxidil, finasteride, azelaic acid, caffeine, retinoic acid, and procapil. Users suggest minoxidil with tretinoin and a 5-alpha reductase inhibitor, while dismissing retinoic and azelaic acids as unnecessary.

      community Lab results from actifolic RU58841

       38 upvotes 2 years ago
      The post discusses the user's experience with hair loss treatment RU58841, which was tested for quality and found to be 96+% pure. The conversation includes various responses, with some users questioning the safety of the product and others expressing satisfaction with the test results.

      community Hair line Mount Rushmore. Bastards lol.

      in Chat  851 upvotes 9 months ago
      Hairlines and hair loss treatments like finasteride and hair transplants. Celebrities' hairlines are discussed, noting genetics and interventions.

      community What's going on with hmi115? The Phase 2 was concluded Nov2024 but no news

       13 upvotes 9 months ago
      Hmi115, a prolactin receptor blocker, showed promise for hair growth, but results from Phase 2 trials have not been published. ABS-201, an AI-based analog, is expected to begin trials in December 2025, while commercialization of treatments like PP-405 is anticipated around 2027.

      community Koshine KX-826 my experience after 2 months, YES, IT'S WORKING!

       16 upvotes 1 year ago
      The user experienced hair regrowth using Koshine KX-826 after two months, noticing new baby hairs and reduced shedding, while continuing to use Hims spray. They reported no side effects from Koshine and plan to keep monitoring progress.

      community Bryan Johnson and his Hair routine, what's the point?

      in Hair Systems  24 upvotes 5 months ago
      Dutasteride and high-dose Minoxidil are the primary treatments maintaining hair, with additional supplements and therapies like red light offering minimal extra benefit. The discussion criticizes promoting expensive hair care products when basic medications are doing most of the work.

      community Is this Progress? - NW7 Diffuse going for the comeback. (49M)

       32 upvotes 6 months ago
      A 49-year-old is using finasteride, minoxidil, tretinoin, and ketoconazole shampoo to combat advanced hair loss and hopes for enough regrowth to consider a hair transplant. Progress is slow, but some improvement is noted by others.

      community Where is GT20029 already? Grrrr

       19 upvotes 2 years ago
      The conversation is about frustration over the delay in phase 2 results for a hair loss treatment called GT20029. One user suspects the treatment may have failed.

      community CoQ10 and Fish Oil body hair growth

       5 upvotes 1 year ago
      Taking CoQ10 and fish oil supplements may lead to increased body hair growth and a crawling sensation on the scalp and skin. The user suspects these supplements could be linked to hair growth, possibly due to their effects on heart health and cholesterol management.

      community Consenus on Kx-826/pyrilutamide vs ru58841

       11 upvotes 1 week ago
      KX-826 is considered effective for hair maintenance, with better safety research than RU58841, but lacks positive anecdotes. RU58841 is seen as potentially stronger, but concerns exist about systemic effects; combining anti-androgens with 5AR inhibitors is suggested for better results.