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      community Female 37/F - On Meds, but no progress. Add PRP?

       4 upvotes 3 years ago
      A 37-year-old woman with androgenetic alopecia is using spironolactone, oral and topical minoxidil, and considering PRP therapy due to lack of progress. She is unable to obtain finasteride, dutasteride, or bicalutamide and is exploring other options like Clascoterone and RU58841.

      community 1 year on fin. No results. I give up.

      in Finasteride/Dutasteride  43 upvotes 3 years ago
      A user who has been taking finasteride, minoxidil, and microneedling for one year with no results, and the replies discuss other treatments, including dutasteride, which is feared due to potential side effects.

      community Finasteride sides on a microdose - what do I do next?

       6 upvotes 4 years ago
      User tried oral and topical finasteride for hair loss but experienced headaches and concentration issues. They ask for advice on whether to continue or try other treatments like alfatradiol, fluridil, or pyrilutamide.

      community Is there a known amount of fin that can reduce serum DHT by only around 25% over the longer term?

       4 upvotes 5 years ago
      The conversation discusses finding a finasteride dosage that reduces DHT by about 25% to minimize side effects, with considerations for topical versus oral formulations. Alternatives like dutasteride mesotherapy and topical treatments are explored, with concerns about systemic absorption and potential impacts on athletic performance and hormone levels.

      community Natural DHT Blockers instead of fin

       4 upvotes 6 years ago
      The conversation discusses using natural DHT blockers like saw palmetto, beta sitosterol, pumpkin seed oil, pygeum africanum bark, and nettle root as alternatives to finasteride for hair loss, with mixed opinions on their effectiveness. Some users report minimal improvement with natural options and better results with finasteride or dutasteride, despite concerns about potential side effects.

      community Committing to Fin/Min every day for the rest of your life?

      in Chat  5 upvotes 5 months ago
      Finasteride and minoxidil are effective for hair loss, with many users finding them manageable as part of a daily routine. Costs can be reduced by purchasing generic versions, and while some users express concerns about long-term use, most agree the benefits outweigh the inconvenience.

      community ABS-201 Trial - What should I know going in

      in Research/Science  28 upvotes 6 months ago
      The conversation is about a user preparing to join the ABS-201 clinical trial for hair loss treatment, which involves a prolactin inhibitor. The user plans to update others on their progress if enrolled.

      community Canadians, is CBSA seizing anageninc RU58841 powder?

       1 upvotes 1 month ago
      The conversation discusses the successful receipt of RU58841 powder in Canada, with no reported issues from a user in British Columbia. The original poster is curious about potential seizures by CBSA but hasn't purchased it yet.

      community Breezula - who tried CB0301/Clascoterone from gray marked/pharmas ?

       1 upvotes 7 months ago
      The conversation discusses using CB0301/Clascoterone as a potential treatment for hair loss, especially for those experiencing side effects from finasteride and dutasteride. The user currently uses oral minoxidil and considers combining it with other treatments like kx826, DHT blocker supplements, and 2% Nizoral shampoo.

      community Clascoterone - clearnet vendor

      in Chat  2 upvotes 8 months ago
      The conversation is about finding a clearnet vendor for clascoterone, also known as Winlevi, for hair loss treatment. The user is seeking recommendations via direct message.

      community Let Me Sell You on NAC

       17 upvotes 7 years ago
      The conversation discusses using NAC (N-Acetyl Cysteine) alongside minoxidil and finasteride for hair loss, with some users noting potential hairline improvement and increased energy. The original poster reduced their finasteride dosage due to mental decline and anxiety, and while NAC's effects on hair are anecdotal, it is considered low-risk with other health benefits.

      community What's the deal with Spectral.DNC-N/'nanoxidil'?

       4 upvotes 3 years ago
      Nanoxidil is considered to have better absorption and fewer side effects than minoxidil, with added DHT blockers. The user is questioning if switching to the more expensive Spectral.DNC-N is worthwhile compared to cheaper options like Kirkland minoxidil.

      community AH-001 another topical AR degrader beside GT20029, completed Phase I

       8 upvotes 10 months ago
      AH-001 is a new topical treatment designed to degrade androgen receptors, targeting the root cause of androgenetic alopecia without the side effects of oral treatments like finasteride. It has shown a strong safety profile and good local tolerability in early trials.

      community ASATONA AG and "Asatex"

       4 upvotes 7 years ago
      The conversation discusses Melatonin's potential benefits for AGA and a product called "Asatex" by ASATONA AG. The company was uncooperative when contacted for purchase inquiries.

      community EMA is re-examining Winlevi (clascoterone at lower concentration)

       8 upvotes 1 year ago
      Clascoterone in Winlevi, a topical AR antagonist, is being re-examined due to concerns about HPA axis suppression in adolescents, but it's unlikely to be banned for adult use in androgenetic alopecia (AGA). The European Medicines Agency recommended refusing Winlevi for acne vulgaris, but this may not affect Breezula's approval for AGA.

      community Capilia Longa and scandinavian biolabs

       2 upvotes 3 years ago
      Capilia Longa and Scandinavian Biolabs are discussed, with skepticism about their effectiveness and value. The conversation suggests avoiding these products due to high cost and perceived lack of results.

      community Black light diagnosis of folliculitis

       3 upvotes 1 month ago
      A user observed orange fluorescence on their nose and hair under a black light, indicating Cutibacterium acnes, which may contribute to hair loss alongside androgenic alopecia. A suggestion was made to use coal tar shampoo to address the issue.

      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

       133 upvotes 2 years ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community ABS-201 KOL Seminar: Dr. Ralf Paus on Human Ex Vivo Hair Regrowth Data

       17 upvotes 8 months ago
      ABS-201 shows promise for male hair regrowth by blocking the prolactin receptor, with higher expected efficacy than current treatments. The discussion also covers dosing differences between macaques and humans for hmi115, highlighting a significant dosage disparity.

      community Going to inject NAD+ and GHL-Cu into Scalp for a few months

      in Chat  1 upvotes 1 year ago
      The conversation discusses a user's plan to inject NAD+ and GHK-Cu into their scalp to improve hair health, with concerns raised about the risks of infection and necrosis. Alternatives like finasteride, dutasteride, microneedling, oral minoxidil, and scalp massages are suggested.