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GlossaryCatagen Phase (catagen follicles)

hair growth stops and follicles shrink, lasting about 2-3 weeks

The Catagen Phase, also known as the Transitional Phase, is a short period in the hair growth cycle that lasts about 2-3 weeks. During this phase, hair growth stops, and the hair follicle shrinks and detaches from the dermal papilla, effectively transitioning the hair from the growth phase (Anagen) to the resting phase (Telogen). This phase is crucial for the renewal of hair follicles and the overall hair growth process.

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community Getting hit hard by the shed….

in Progress Pictures 85 upvotes 2 months ago

A user is experiencing significant hair shedding after starting a treatment regimen of 1mg oral finasteride, 3mg oral minoxidil, 2.5mg biotin, and vitamins. Despite the shedding, they remain optimistic and plan to continue the treatment for a year before making any conclusions.

community New and Interesting HairLoss Studies/Papers/Reviews

in Treatment 42 upvotes 4 years ago

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

community HLT Megathread on HMI-115 (key takeaways in comments)

in Research/Science 39 upvotes 1 year ago

HMI-115, a newly discovered hair loss treatment that could potentially be effective for those with diffuse thinning and telogen effluvium. It is based on prolactin receptor antagonist signaling and has already undergone Phase I trials in women, with potential commercialization by 2027.

community My scalp punch biopsy results🤔?

in Female 7 upvotes 1 year ago

Female using Rogaine foam for hair loss had scalp punch biopsy, diagnosed with Androgenetic Alopecia (AGA). Doctor recommended starting Spironolactone 50mg.

community Progress with 6 Years fin and a FUT (2017 vs 2023)

in Is this regrowth? 210 upvotes 1 year ago

The post discusses a user's six-year progress with finasteride and a Follicular Unit Transplant (FUT) for hair loss. The user shared before and after photos in reverse order, leading to confusion, but overall, the community responded positively to the user's hair regrowth.

community A concise, easy-to-understand post on Androgenic Alopecia theory and its practical applications

in Research/Science 92 upvotes 2 years ago

The mechanism of Androgenic Alopecia and practical applications of treatments like Minoxidil, Finasteride, RU58841, dermarolling, scalp massages, anti-fungals, progesterone, estrogen, PPAR-γ activators, reducing oxidative stress, and scalp exercises. It explains why DHT is important in AA and how other factors might be involved such as hypoxia, increased DKK-1 expression, morphological changes to the scalp, skull growth during childhood/puberty, and blood flow.

community Why HMI115 should work if it doesn’t affect dht?

in Research/Science 16 upvotes 1 year ago

Hair growth can be induced without stopping DHT, as seen with Minoxidil. HMI115 may work by promoting follicle growth, not targeting the root cause of hair loss (DHT).

community Losing gains from 7 months of oral min, fin, dut.

in Update 66 upvotes 9 months ago

A user reported losing hair after 7 months of using oral minoxidil, finasteride, and dutasteride, but others reassured that this is likely just a shedding phase where old hairs fall out to make way for new growth. Some users experience sheds every 7-8 months and suggest staying consistent with treatment.

community Sandalore: a scientific homemade approch

20 upvotes 5 years ago

The post discusses using Sandalore as a potential hair loss treatment, emphasizing precise measurements and safe handling. The user compares Sandalore's effects to Minoxidil and mentions preparing a solution with ethanol and DMSO.

community A side to side comparison, two and half months apart

in Progress Pictures 212 upvotes 4 weeks ago

A user shared progress pictures showing hair improvement after using oral finasteride and topical minoxidil for two and a half months. They are considering a hair transplant but are advised to wait for full results from the treatments.

community A lot of hair falling out like this, what does it mean? Diffuse thinning, chronic dandruff and scalp crust (seborrheic dermatitis), 28 y/o male

in Research/Science 35 upvotes 2 years ago

A 28 year old male experiencing diffuse thinning, chronic dandruff and scalp crust (seborrheic dermatitis), with replies discussing the use of topical fin for hormone imbalances and Nizoral for seb derm.

community 5 Month Dutasteride Progress Before and After

in Progress Pictures 173 upvotes 10 months ago

A user experiencing significant hair loss started using Dutasteride, a drug typically used for prostate issues, and noticed a positive change in hair thickness and volume after 5 months. Other users in the conversation also shared their experiences and observations with Dutasteride, with one mentioning additional use of oral Minoxidil.

community 1 year of finasteride 1.25 mg daily. 21->22 years old.

in Progress Pictures 695 upvotes 1 year ago

The conclusion of the conversation is that the user experienced significant hair regrowth after taking finasteride for a year. They did not use any other treatments and did not experience any noticeable side effects.

community Tretinoin, any good, what’s your experience

in Research/Science 21 upvotes 3 months ago

The conversation discusses using tretinoin for hair loss and skincare. Users share experiences, noting tretinoin's effectiveness in combination with minoxidil for hair and its proven benefits for anti-aging skincare.

community DHT/Testosterone levels in scalp Fin VS Dut.

in Finasteride/Dutasteride 60 upvotes 1 month ago

Dutasteride raises scalp testosterone by 99%, which may not be ideal for those sensitive to all androgens. Some argue finasteride's balancing act might be better, while others believe dutasteride is superior for hair regrowth.

community TDM-105795, a new hair loss treatment that actually works!

in Treatment 44 upvotes 6 months ago

A new hair loss treatment called TDM-105795 is discussed as a potential replacement or add-on to Minoxidil. Users express hope for new effective treatments.

community Pyrilutamide update: three months

in Update 29 upvotes 1 year ago

A user's 3-month experience with pyrilutamide to reduce hair shedding, and how it may not be strong enough to stop the thinning of their hairline. Other users mentioned the effectiveness of minoxidil and finasteride for treating hair loss.

community My journey from Norwood 3.5/4 to Norwood 0

in Transplants 250 upvotes 5 months ago

A user's hair regrowth journey involved a hair transplant and using RU58841, finasteride, and minoxidil, with side effects managed by other medications.

community HMI-115 update: Chime Biologics and Hope Medicine Enter Manufacturing Agreement to Speed up the Launch of First-in-class Antibody Drug HMI-115 Targeting Endometriosis and Androgenic Alopecia

in Research/Science 110 upvotes 10 months ago

Chime Biologics and Hope Medicine are speeding up the launch of a first-in-class antibody drug, HMI-115, for endometriosis and androgenic alopecia. The treatment involves a series of subcutaneous injections, has shown promising results in phase 1, and continues to promote hair regrowth even after the treatment is stopped.

community TWIST-1 and the cure: Is it really that easy?

in Research/Science 283 upvotes 2 years ago

TWIST-1 gene's role in hair loss and potential as a treatment target. Inhibiting TWIST-1 may prolong hair growth and reduce hair follicle sensitivity to DHT.

community so pissed off at the world. hairloss is a nightmare in your early 20's (WARNING, RANT)

in Treatment 153 upvotes 2 years ago

User frustrated with lack of results from finasteride and minoxidil for hair loss. Others suggest checking for other health issues, focusing on fitness, and considering alternative treatments.

community About the CBD regrowth study : just a few remarks

in Research/Science 167 upvotes 3 years ago

CBD in an emu and lanolin oil preparation showed a 100% increase in hair growth, but the effectiveness may partly come from the oils. Users discussed proper CBD dosage, preparation methods, and skepticism about the study's quality.

community 2 months topical dutasteride plus minoxidil, very happy with the results!

in Finasteride/Dutasteride 336 upvotes 3 years ago

A user's success in treating their hair loss with 2x daily topical dutasteride and minoxidil, as well as the potential for using less frequent application of topical dutasteride due to its long half-life.

community Fevipiprant 2019!

17 upvotes 7 years ago

The conversation discusses Fevipiprant, an asthma drug that may block CRTH2 and potentially stop male pattern baldness (MPB) without inhibiting DHT. It also mentions the use of finasteride and dutasteride for hair loss.