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A 26-year-old is considering switching from a regimen of minoxidil, finasteride, and RU58841 to possibly include pyrilutamide due to insufficient results in slowing hair loss. They are seeking advice on whether to add pyrilutamide or replace RU58841 with it, considering cost and effectiveness.

People are discussing their reactions if PP405 fails in phase 3 trials, with some expressing skepticism and others holding onto hope for future treatments like GT20029 and Breezula. Many mention continuing with existing treatments like minoxidil and finasteride, while others express disappointment and consider alternative solutions.

Pyrilutamide 1% is being used for hair loss, with some users experiencing shedding but no regrowth yet. It may be too early to see results.

A user shared their one-year progress using finasteride 1.2mg and minoxidil 3mg daily, noting initial shedding and a slight drop in libido that improved over time. They also switched to Aussie Miracle Volume shampoo and use Hims supplements, including vitamins and biotin.

A user with mild psoriasis on the scalp is using finasteride, topical minoxidil, and dermarolling for hair loss but plans to stop minoxidil on the crown due to psoriasis aggravation. Suggestions include switching to a lipid-based minoxidil, using Ketoconazole shampoo, or trying oral minoxidil.

Using minoxidil twice daily may offer around 20% better regrowth compared to once daily, but once daily is still effective, especially with dermastamping. The user also uses dutasteride and finasteride daily, and is considering increasing minoxidil application despite concerns about cost and potential shedding.

The user experienced significant hair thickening after one year of using chewable finasteride (1.2 mg) and minoxidil (2.5 mg) without major side effects, except occasional low libido. The user sourced the treatments from Hims and noticed results around 5-6 months, with shedding lasting about two months.

PP405 shows promise in regenerating hair by activating dormant follicles. Other treatments like VDPHL01 and Breezula are also advancing, providing new hope for hair loss solutions.

A user shared progress pictures after 40 days of using topical finasteride, minoxidil, and KX-826 following a hair transplant. They previously used Polaris NR-11, which contains finasteride and minoxidil, and experienced significant hair regrowth.

The user reports using Finasteride 1.1 mg, Minoxidil 3 mg, Biotin daily, and occasionally a dermapen from May 24 to July 22. They observe some improvement in hair regrowth, especially around the temples and crown.

PP405 shows promise in reactivating dormant hair follicles, with early trials indicating some success, but it is not yet a proven treatment for hair loss. Users are advised to be cautious with unverified versions, and further research is needed to confirm its effectiveness compared to treatments like minoxidil and finasteride.

Nanoxidil is considered by some as a substitute for Minoxidil, but users report it as ineffective and expensive. Finasteride is recommended as a more effective treatment, often used with Minoxidil, microneedling, and ketoconazole.

The user saw hair improvement with minoxidil, finasteride, and a red light cap, noting better results after adding finasteride and stressing routine consistency.

Using topical finasteride once a week for hair loss. Dutasteride may be more effective due to its longer half-life.

The conversation discusses using topical finasteride as an alternative to oral medication for hair loss, with mentions of minoxidil, microneedling, ketoconazole shampoo, and other treatments. A user shares their experience with topical finasteride and other treatments, noting improved hair density.

A user experienced positive hair growth results using 5% topical minoxidil for a year and 1 mg finasteride for four months but is considering stopping finasteride due to persistent side effects like libido loss. Others in the conversation discuss similar experiences, suggest trying topical finasteride to reduce side effects, and emphasize the importance of overall health and lifestyle.

The conversation is about purchasing KX-826 (Pyrilutamide) on Amazon, now called Koshine. A user mentioned their order is expected to arrive between August 22 and September 13.

OP shared a 100-day progress on reducing hair shedding using Minoxidil and Dorpang scalp serum, noting healthier hair growth. Other users discussed their own treatments, including Minoxidil, ketoconazole, saw palmetto, and pumpkin seed oil, with some considering finasteride if needed.

A user is considering a hair loss treatment lotion containing minoxidil, adenosine, caffeine, melatonin, and azelaic acid, questioning the interaction between caffeine and adenosine receptors. Another user suggests adding a topical anti-DHT ingredient like spironolactone, noting it should not be taken orally by men.

Minoxidil and finasteride are discussed for hair loss, with concerns about minoxidil's heart-related side effects. New treatments like PP405 are met with skepticism, often humorously noted as always being "five years away."

A user is seeking a titanium dioxide-free finasteride pill due to health concerns. They have not found a suitable supplier yet.

PP405 is a new drug in Phase 2 trials for hair loss, generating cautious optimism among users. Some users are currently using finasteride and experiencing side effects, while others are skeptical about unapproved products being sold.

The user experienced uncomfortable side effects, including loss of libido, brain fog, and nipple sensitivity, after starting finasteride for hair loss. They are considering stopping the medication due to concerns about gynecomastia and personality changes.

Finasteride improved the user's hair texture and growth, with some initial side effects like libido loss that eventually subsided. The user advises considering lifestyle factors alongside treatment and encourages others to start finasteride if hesitant.

The user is experiencing diffuse thinning and receded hairline, using dutasteride, minoxidil, and ketoconazole without regrowth, and was prescribed clobetasol propionate 0.05% with salicylic acid for possible inflammation. Other users caution against using the strong steroid without a serious condition, sharing experiences of adverse effects and alternative treatments for scalp issues.

A 30-year-old started using 0.5mg finasteride and 5% minoxidil once daily for hair loss, experiencing positive results with minimal side effects after 4 months. The user warns about minoxidil's toxicity to cats.

The user experienced positive hair regrowth and thicker hair after 12 weeks on 1.25mg Finasteride and 2.5mg Minoxidil chewables, with no side effects. They plan to reassess the need for a hair transplant after seeing further progress.

A person experienced hair regrowth after reducing testosterone levels and using saw palmetto tincture and Alpecin shampoo. Other users suggested treatments like Nizoral shampoo, Aldactone, and supplements for hair loss.

The conversation humorously discusses hair loss treatments, mentioning Minoxidil, finasteride, and RU58841. It jokingly suggests the creation of a new chemical called RU99999.

The user is considering using Tacrolimus Solution and topical Dutasteride to avoid shedding caused by Minoxidil, which they fear may lead to facial side effects. They are also concerned about scalp sensitivity and are exploring different treatment bases to manage seborrheic dermatitis.