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      community 24M – aggressive shedding, past success with mesotherapy + minoxidil, now worse than before. Unsure if I should try a combo or consider a transplant.

       12 upvotes 9 months ago
      A 24-year-old is experiencing aggressive hair shedding despite past success with mesotherapy and minoxidil, and is considering adding treatments like Expecia, dermapen, or a hair transplant. Many suggest using finasteride to maintain hair, as it is necessary even after a transplant, and side effects are rare and reversible.

      community Reducing Fibrosis in Hair Loss: Topical Pirfenidone

       59 upvotes 5 months ago
      Topical pirfenidone is highlighted as an effective anti-inflammatory and anti-fibrotic treatment for hair loss, particularly in addressing perifollicular fibrosis, which may enhance the effectiveness of standard treatments like finasteride and minoxidil. The user also uses calcipotriol, MCT oil, ciclopirox shampoo, and benzoyl peroxide shampoo as part of their regimen.

      community Clascoterone - Why are there so few posts if it’s already on the market?

      in Chat  34 upvotes 8 months ago
      Clascoterone is being discussed for hair loss, but its current acne formulation may not be suitable for scalp use due to potential skin irritation and lower dosage compared to Breezula. Users mention other treatments like finasteride, minoxidil, and pyrilutamide, with some expressing skepticism about clascoterone's effectiveness for hair loss.

      community Question about clascoterone acne cream

       2 upvotes 5 months ago
      Clascoterone cream can be used on the scalp, but it may not be effective due to its dosage. AR antagonists like clascoterone are generally less effective than 5AR inhibitors for hair loss.

      community Telogen Effluvium/Chronic TE and immune-related hair loss advice

       5 upvotes 8 years ago
      Chronic Telogen Effluvium can be managed by avoiding inflammatory foods, exercising, staying hydrated, and using supplements like krill oil, saw palmetto, or licorice root. Minoxidil is discouraged due to its cost and potential for worsening hair loss, while castor oil is recommended to strengthen hair roots and reduce shedding.

      community About to throw in towel. I just don't know anymore

      in Treatment  9 upvotes 1 year ago
      The user is experiencing severe side effects from finasteride, including sleep issues, depression, and gynecomastia, and is considering stopping the medication. They are exploring other treatments like RU58841 and dutasteride but are hesitant due to potential side effects.

      community month and a half update,

       4 upvotes 5 years ago
      The user is experiencing severe hair shedding after using RU58841, stemoxydine, and minoxidil, and has stopped using finasteride due to side effects. They hope the shedding is temporary and will lead to regrowth.

      community 2026 Hairloss Nuclear Stack Update

       83 upvotes 6 months ago
      A user shared an extensive hair loss treatment regimen including dutasteride, minoxidil, tadalafil, RU58841, microneedling, and various topical and oral supplements. Responses varied, with some suggesting the regimen is excessive and others offering additional advice or expressing skepticism about its practicality and effectiveness.

      community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

       63 upvotes 2 years ago
      Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

      community Losing Transplanted Hair... HELP

       5 upvotes 3 years ago
      The user experienced hair loss in transplanted areas despite using finasteride and minoxidil, suspecting creatine as a cause. Suggestions included stopping creatine, considering dutasteride, and focusing on a healthy diet.

      community Massive shed after starting a caffeine shampoo? Am panicking.

       4 upvotes 5 years ago
      The user experienced significant hair shedding after starting a caffeine shampoo called Alpecin, despite being on finasteride and switching to dutasteride. The doctor suggested the shedding might be due to new hair growth, while others speculated it could be from switching medications or the shampoo's ineffectiveness.

      community Crazy 6 month oral minoxidil and GHK-CU transformation

       266 upvotes 2 months ago
      The user shared a 6-month update on using oral minoxidil and GHK-Cu for hair regrowth, noting significant improvement and increased confidence. Some commenters questioned the authenticity of the transformation, mentioning visible hair fibers, while others discussed the role of DHT blockers and religious perspectives.

      community M24, very mentally unwell and I don’t know what to do

      in Chat  13 upvotes 1 month ago
      A 24-year-old is struggling with severe mental distress due to hair loss despite using dutasteride, oral minoxidil, and having a hair transplant. Many responders suggest focusing on mental health, trying different hairstyles, and accepting imperfections.

      community Question.. ( Come check )

      7 years ago
      A user has been losing hair for two and a half years after a tropical trip and illness. A dermatologist prescribed betamethasone valerate 0.1% lotion, but the user is unsure if it's safe or effective for general hair loss.

      community Still losing ground after 10 months dut + minox

       3 upvotes 1 month ago
      The user has been using a combination of dutasteride, minoxidil, and biotin for hair loss but is experiencing a decline in hair condition after initial improvement. They are considering consulting a trichologist and switching from capsule to softgel format for better absorption.

      community Anyone have multi week sheds from ru?

      in Chat  2 upvotes 1 year ago
      The user experienced increased hair shedding after using RU58841, despite initial improvements in scalp condition and appearance. They are considering stopping RU58841 to see if shedding decreases.

      community My good/bad experience with Creatine

       27 upvotes 1 year ago
      Creatine may cause increased hair shedding in some individuals, especially those with androgenetic alopecia (AGA), despite its physical performance benefits. Many users report stopping creatine to reduce hair loss, while others believe the effects are anecdotal or due to other factors like increased physical activity.

      community Anyone heard of or have experience using baricitinib?

       1 upvotes 3 years ago
      The conversation is about baricitinib, a medicine that can help with hair loss, and why it isn't more popular or widely discussed. No specific experiences with the treatment were shared.

      community Pp405 trials question - 2a/2b,

       6 upvotes 10 months ago
      PP405 trials have completed phase 2a, showing promising results with a 31% stat for hair density increase, and are moving directly to phase 3. Detailed results will be presented at a medical conference in 2026.

      community five yeras journey fighting hairloss

       157 upvotes 1 month ago
      The user has been battling hair loss for five years using Minoxidil, Finasteride, and Dutasteride. Despite some improvements, hair loss persists, and they are considering dietary changes and other treatments for seborrheic dermatitis and hyperhidrosis.

      community I think I’ve finally found the reason for my hair loss

      in Chat  98 upvotes 1 year ago
      The user experienced hair loss since 2019 and tried finasteride, dutasteride, RU58841, and ketoconazole shampoo without success. A scalp biopsy showed scarring and inflammation from folliculitis, indicating chronic inflammation was affecting treatment effectiveness.

      community Been on min+fin for 2 years, only gotten worse. B/A pics included

      in Chat  88 upvotes 7 months ago
      The user experienced worsening hair loss despite using finasteride and topical minoxidil for two years and is considering oral minoxidil and dutasteride. Suggestions include microneedling, stress management, and alternative treatments like topical finasteride or ketoconazole shampoo.