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      community A hill on which I will die: The DHT itch absolutely exists

      in Research/Science  208 upvotes 6 months ago
      The DHT itch is linked to hair loss and persists despite finasteride use; switching to dutasteride helped alleviate the itch and promoted regrowth. Some users suggest seborrheic dermatitis as a cause and recommend treatments like medicated shampoos, vitamin D, and minoxidil.

      community HMI 115 Phase 2 - Leaked pics from Discord

      in Research/Science  359 upvotes 6 months ago
      The conversation discusses HMI 115, a new hair loss treatment with promising results, showing a significant increase in hair density after two months. Some users are skeptical, while others are hopeful for its release and potential affordability.

      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

      in Research/Science  136 upvotes 7 months ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community Fibrosing alopecia in a pattern distribution

      in Research/Science  14 upvotes 8 months ago
      A user has been experiencing hair loss for 4 years, with treatments like minoxidil, finasteride, and various supplements proving ineffective. They were diagnosed with fibrosing alopecia in a pattern distribution, a condition that may require a combination of anti-inflammatory and hair growth treatments.

      community Is there any new drug that looks promising ?

      in Research/Science  25 upvotes 8 months ago
      The conversation discusses GT20029, a drug in Phase II trials that targets androgen receptors with minimal systemic effects, and TDM-105795, a growth stimulant with a different mechanism than minoxidil that may revive papilla stem cells. Both are potential new treatments for hair loss.

      community Creatine's effect on Hair Loss and DHT

      in Research/Science  103 upvotes 8 months ago
      A 21-year-old male managed to control his hair loss using Nizoral, RU58841, and finasteride, but experienced increased scalp itchiness after starting creatine, which subsided upon stopping creatine. Users shared mixed experiences on whether creatine affects hair loss, with some reporting negative effects and others seeing no change or defending its benefits.

      community Does microneedling damage scalp?

      in Research/Science  12 upvotes 9 months ago
      Microneedling does not prevent future hair transplants, but some surgeons report the skin becomes "harder" in treated areas. There is no clear evidence to confirm this effect.

      community Does lowering serum prolactin lower prolactin in the scalp?

      in Research/Science  13 upvotes 9 months ago
      The conversation discusses whether not masturbating (semen retention) affects hair loss, with opinions varying but generally dismissing the idea. Some participants mention using hair loss treatments like Minoxidil, Finasteride, and RU58841, but the effectiveness and relation to prolactin levels in the scalp are debated.

      community Why isn’t anyone talking about this?

      in Research/Science  31 upvotes 10 months ago
      Hair cloning is being developed by companies like Kangstem Biotech and Stemson, with potential availability in a few years. Initial costs are expected to be high, but prices may decrease over time.

      community Hair Loss Drugs Ranked in Order of Efficacy

      in Research/Science  67 upvotes 11 months ago
      Dutasteride is likely the most effective treatment for male pattern baldness, followed by finasteride and minoxidil in various forms and dosages. Users discuss personal experiences, dosages, and potential side effects, with some considering combining treatments for better results.

      community Vertoporfin research update by Dr Bloxham

      in Research/Science  71 upvotes 1 year ago
      The conversation discusses the potential of verteporfin in treating hair loss, with some users reporting positive results and speculating that it could lead to a cure for baldness. Others are skeptical, and there's a debate on the effectiveness of verteporfin for regrowing hair and reducing transplant scars.

      community Androgenetic alopecia is a skin disease: DHT-mediated skin disorders

      in Research/Science  65 upvotes 1 year ago
      Dihydrotestosterone (DHT) impacts various skin conditions, including Androgenetic alopecia and seborrheic dermatitis, by causing overactivity in sebaceous glands. Topical medications Tacrolimus and Clobetasol can reduce these inflammatory conditions, and treatments like RU58841, Minoxidil, and Finasteride may also be beneficial.

      community I just made my own PRP - DIY PRP

      in Research/Science  549 upvotes 1 year ago
      The post and conversation are about a user who made their own Platelet-Rich Plasma (PRP) for hair loss treatment at home, using their own blood and a centrifuge. The responses vary, with some users supporting the DIY approach to save money, others expressing concern about the safety and effectiveness of the method, and a few joking about the lengths people will go to combat hair loss.

      community Why is it barely impossible to find balding South Korean men

      in Research/Science  244 upvotes 1 year ago
      The post discusses the rarity of baldness among South Korean men. Users suggest this could be due to early treatment, high beauty standards, accessibility of healthcare, and genetics. Treatments like finasteride and dutasteride are commonly used, and hair transplants are also popular.

      community Testosterone and hair loss seeming irrelevance

      in Research/Science  81 upvotes 1 year ago
      The conversation is about the role of testosterone in hair loss and the effectiveness of different treatments. The conclusion is that DHT is the main culprit for hair loss, and finasteride has been proven to work long-term in maintaining and regrowing hair. Testosterone may have a minor effect, but it is not the primary cause of hair loss.

      community Oral Minoxidil and Grapefruit Juice

      in Research/Science  96 upvotes 1 year ago
      The conversation is about the potential dangers of taking oral minoxidil and grapefruit juice together. Some users express concern about dangerous drug interactions, while others argue that grapefruit juice may inhibit the metabolism of finasteride. The conclusion is that grapefruit juice may make finasteride less effective, but it won't affect minoxidil.

      community Hair loss treatments rated (by gpt-4)

      in Research/Science  248 upvotes 1 year ago
      Rating treatments for hair loss, with the help of GPT-4, according to efficacy, evidence and tolerability; a combination of chemicals from research papers, custom compounds, and some suggestions from other users were included.