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      community Longterm ru58841 users + my experience

      in Treatment  7 upvotes 2 months ago
      RU58841 users report mixed results, with some experiencing no benefits and others noting regrowth but potential side effects. Many prefer finasteride and minoxidil due to better-studied safety profiles.

      community Severe Hair loss after stopping Rogaine

      in Minoxidil  12 upvotes 2 months ago
      A 32-year-old male experienced severe hair loss after stopping Rogaine and is considering restarting it along with topical Finasteride and Ketoconazole shampoo due to concerns about oral Finasteride causing gynecomastia. Users suggest that stopping Minoxidil can lead to significant hair loss and recommend Finasteride for better results.

      community Oral Minoxidil worse hair after 1 year

      in Progress Pictures  41 upvotes 2 months ago
      The user switched from topical to oral Minoxidil and Finasteride but saw no improvement after a year, with hair appearing thinner. They recently switched to Dutasteride, hoping for better results.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 3 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community 8 months into Finasteride and Minoxidil (17M)

      in Is this regrowth?  1 upvotes 3 months ago
      A 17-year-old has been using minoxidil, microneedling, and finasteride for hair loss, with added tretinoin for better absorption. They are seeking opinions on their progress and the use of finasteride as a teenager.

      community Is a topical serum as effective as a topical spray?

      in Finasteride/Dutasteride  6 upvotes 3 months ago
      The post discusses whether a topical serum with 0.3% finasteride, 6% minoxidil, and essential oils is as effective as a spray with the same concentrations but different ingredients for scalp absorption. The user is seeking advice on which formulation absorbs better into the scalp.
      Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI?

      community Topical Dutasteride - Non-Hormonal, Side Effect Free 5ARI?

      in Treatments  434 upvotes 3 months ago
      Topical dutasteride is suggested as a low side-effect treatment for hair loss, with a proposed dose of 0.025% 1ml/day. It is considered better than finasteride due to its even inhibition of DHT isoforms and lower systemic absorption.

      community DHT/Testosterone levels in scalp Fin VS Dut.

      in Finasteride/Dutasteride  60 upvotes 4 months ago
      Dutasteride raises scalp testosterone by 99%, which may not be ideal for those sensitive to all androgens. Some argue finasteride's balancing act might be better, while others believe dutasteride is superior for hair regrowth.

      community 1,5 month fin 1mg + min 5% progress

      in Progress Pictures  23 upvotes 4 months ago
      A 21-year-old male has been using finasteride 1mg and minoxidil 5% daily for 45 days, noticing some new hair growth but continued hair loss. A reply suggests he is likely shedding and should give it more time for better results.

      community Finasteride before and after 6 years

      in Progress Pictures  227 upvotes 4 months ago
      A user shared progress pictures after 6 years of using finasteride, showing maintained hair with no regrowth. Suggestions included possibly adding minoxidil and switching to dutasteride for better results.

      community 3 months progress - fin / min.

      in Progress Pictures  109 upvotes 5 months ago
      A user shared their 3-month progress using 1mg oral finasteride daily and applying topical minoxidil once daily, noting no side effects and darker hair. Another user praised the progress, anticipating even better results at the 6-month mark.

      community Has anyone had positive experiences with Dutasteride?

      in Finasteride/Dutasteride  21 upvotes 5 months ago
      Dutasteride is generally considered more effective than finasteride for hair regrowth and thickening, despite some negative anecdotal reports. Users report thicker hair and better skin with dutasteride, and some believe negative reviews are due to advanced alopecia or impatience with the shedding process.

      community Progress from Jan-June this year

      in Progress Pictures  82 upvotes 5 months ago
      User shared progress using topical Finasteride 0.3% and Minoxidil 6% daily since January, noting some improvement and no side effects. Considering adding derma rolling for better results.

      community Best Shampoo Recommendations!!

      in Product  12 upvotes 5 months ago
      A user is seeking shampoo recommendations for thinning hair that doesn't cause dryness or brittleness. Another user suggests Pura D'or, noting it makes their hair feel better despite thinning, but mentions no shampoo will help with hair loss.