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      community GT20029 China Phase II Trial For AGA Reached Primary Endpoint

       133 upvotes 2 years ago
      The GT20029 tincture, a topical androgen receptor degrader, showed significant hair growth and good safety in a China Phase II trial for male androgenetic alopecia (AGA), with the 1% dose twice weekly identified as optimal. The company plans to initiate Phase III trials in China and Phase II in the U.S., and the treatment also shows promise for acne.

      community Bloodwork on 0.5mg dutasteride

       4 upvotes 5 days ago
      The conversation discusses using 0.5mg dutasteride for hair loss and the decision to switch back to finasteride pills due to insufficient suppression. It highlights the importance of drug formulation and potential issues with absorption or degradation.

      community PP405 (Everychem 3HP) Users, share your story!

      in Chat  32 upvotes 5 months ago
      Everychem's solution, similar to PP405, has mixed results for hair regrowth, with some users reporting improvements and others seeing no change or worsening hair loss. Users are sharing experiences and updates to determine its effectiveness.

      community PP405: The Ultimate Hair Loss Drug for Complete Hair Growth

       211 upvotes 1 year ago
      PP405 is a new hair loss treatment in phase 2 trials that may promote hair growth by increasing lactate production and activating hair follicle stem cells. It could potentially replace hormone-disrupting treatments like Minoxidil and finasteride.

      community Chat is this real? Compound called clascoterone

       581 upvotes 9 months ago
      Clascoterone shows promising results for hair regrowth in men with androgenetic alopecia, with potential FDA approval by 2026. It acts as a topical androgen receptor blocker, offering a new treatment option with minimal side effects compared to existing treatments like finasteride.

      community Topical melatonin shows some promise.

       4 upvotes 10 years ago
      Topical melatonin shows promise for increasing hair density with minimal side effects. The user is transitioning from oral finasteride to a compounded minoxidil and finasteride solution and considering melatonin and bimatoprost as additional treatments.

      community Sebum production even on dutasteride, and its relation to MPB.

      in Finasteride/Dutasteride  6 upvotes 9 months ago
      The conversation discusses managing hair loss and scalp issues, with users sharing experiences using treatments like dutasteride, finasteride, ketoconazole, sulfur soap, and topical anti-androgens. Suggestions include trying sulfur soap, scalp massages, spironolactone, and dietary changes to reduce sebum production and dandruff.

      community Every potentially effective vitamin and minerals?

       3 upvotes 4 years ago
      The conversation discusses hair loss treatments, specifically mentioning Minoxidil, finasteride, and RU58841, and the role of vitamins like Vitamin D3 and Biotin. It concludes that while vitamins may not directly help with androgenetic alopecia (AGA), they might be beneficial if deficiencies are present.

      community Locklabs + Dutasteride Formula

       1 upvotes 8 months ago
      The conversation discusses the effectiveness and value of a Locklabs pill containing finasteride, minoxidil, biotin, and a low dose of dutasteride for hair loss. The user is uncertain if the .1mg dutasteride dosage is sufficient and worth the cost.

      community Reason why placebo group got regrow on trial phase 3

      in Chat  16 upvotes 2 years ago
      Placebo hair regrowth might be influenced by propylene glycol in lotions or participants lying about using other treatments like minoxidil, finasteride, or microneedling. Being part of a study can also improve hair health due to lifestyle changes.

      community Additional supplements for min/fin treatment?

       5 upvotes 10 months ago
      Consider taking vitamin D3 and using tretinoin with minoxidil and finasteride for hair loss. Rosemary essential oil may improve hair appearance.

      community Sandalore (Givaudan) concentration application

       9 upvotes 7 years ago
      The conversation discusses using Sandalore for hair loss treatment, with a focus on finding the correct concentration for a topical lotion. The consensus is to start with a 0.1% concentration due to potential scalp irritation at higher levels.

      community Best supplements to compliment finasteride protocol

       17 upvotes 1 month ago
      The conversation discusses supplementing a finasteride regimen for hair loss with Omega 3, Vitamin D/K, Zinc, probiotics, and possibly adding oral minoxidil, magnesium, astaxanthin, and B vitamins. Users suggest testing nutrient levels before adding supplements like zinc and iron, and consider biotin, keratin, and possibly switching to dutasteride or adding topical minoxidil.

      community Serum based on plant extracts boosts hair growth in weeks.

       44 upvotes 11 months ago
      A serum containing Centella asiatica extracellular vesicles, IGF-1, FGF-7, and caffeine significantly improved hair thickness, density, length, and reduced hair loss after 56 days. The conversation also discusses how treatments like finasteride, minoxidil, and ketoconazole address different aspects of hair loss by reducing DHT, improving blood flow, and lowering inflammation.

      community Has anyone done research on Absci's AI‑driven antibody platform? Seeking your thoughts!

       4 upvotes 1 year ago
      A user is interested in Absci's AI-driven antibody platform, ABS-201, for treating androgenetic alopecia, which shows promising preclinical results and potential for hair regrowth and pigmentation restoration. However, concerns are raised about the drug's development timeline and its advantages compared to existing treatments.

      community RU-58441 Janoshik test result of Made-In-China Supplier

       29 upvotes 9 months ago
      A user ordered RU58841 from a Chinese supplier, found it to be less than 99% pure, and plans to try a different seller next time. Concerns were raised about impurities, but the user believes they are likely inactive fillers rather than harmful substances.

      community Is this legitimate dutasteride?

      in Finasteride/Dutasteride  18 upvotes 2 months ago
      Dutasteride tablets are considered legitimate and effective, though some users believe gel capsules may be more effective. The conversation discusses the legitimacy of tablets from stop99bald and the differences in bioavailability between tablet and gel forms.

      community Result of my cortisol, prolactin, testosterone, ACTH blood test,

      10 months ago
      OP is using 5% minoxidil and a foligain supplement for hair loss, with blood test results showing high cortisol levels. OP is considering starting finasteride, while another user shares their experience with finasteride and hair loss challenges due to malabsorption issues.