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      community Losing the genetic lottery - venting

      in Chat  67 upvotes 4 months ago
      The user is experiencing hair loss and has tried various treatments including topical and oral finasteride, minoxidil, dutasteride, and ketoconazole, but continues to lose hair. They are considering alternative solutions like hair systems due to the lack of improvement and a scalp condition called CVG.

      community My new experiment: Topical dut with oral fin

       5 upvotes 4 days ago
      A 45-year-old man is using oral finasteride, oral minoxidil, tretinoin, and microneedling for hair regrowth, with plans to add topical dutasteride to improve his hairline. He is considering a hair transplant but is cautious about changing his current regimen.

      community Anyone here used spirolactone/cyproterone acetate/bicalutamide?

       4 upvotes 1 year ago
      The conversation discusses the use of spironolactone, cyproterone acetate, and bicalutamide for hair loss, with concerns about side effects like gynecomastia and depression. Topical spironolactone is considered safe for men and effective when combined with regular treatments.

      community 11mth daily 0.5mg oral finasteride

      in Finasteride/Dutasteride  835 upvotes 1 year ago
      The user experienced significant hair regrowth with 0.5mg oral finasteride daily, despite a minoxidil allergy, and reported no side effects. They also used a keto shampoo and were satisfied with the results.

      community 1.25 mg of both loniten and finasteride since 9/18/25

       6 upvotes 5 months ago
      The user has been using 1.25 mg of oral minoxidil and finasteride since September 2025 to address diffuse hair thinning, and is considering trying a new shampoo. Other users suggest increasing the minoxidil dose and trying dutasteride.

      community I wish pp405 work and i have full head of hair in 2028-2030

      in Chat  106 upvotes 10 months ago
      People are hopeful about future hair loss treatments like PP405, GT20029, and VDPHL01, while some are currently using finasteride and minoxidil. There is skepticism about the effectiveness of new treatments, and some advise against hair transplants until more promising drugs are available.

      community 5 month Progress (18m)

       32 upvotes 6 years ago
      An 18-year-old shares a 5-month hair loss treatment progress using finasteride, minoxidil, microneedling, Nizoral, biotin, and fish oil. The user discusses the effectiveness of finasteride over time and considers continuing the regimen despite suggestions to simplify it.

      community A concern regarding the upcoming androgen degrader drug GT20029

       11 upvotes 1 year ago
      GT20029 is a topical treatment that degrades androgen receptors to prevent hair thinning and loss, potentially offering fewer side effects than systemic treatments like finasteride. Concerns include its impact on hair texture and potential systemic effects, with market availability speculated in 3 to 5 years.

      community New York Magazine article - the Great Unbalding

       48 upvotes 1 year ago
      PP405, a potential treatment for male pattern baldness, shows promise with some participants experiencing hair regrowth in early trials. However, it is not yet considered a cure and may be used alongside existing treatments like minoxidil and finasteride.

      community M21. Fin/Dut/Minox hair loss jorney

       8 upvotes 1 month ago
      A 21-year-old shares their hair loss journey, starting treatment at 18 with finasteride, oral minoxidil, biotin, and vitamins, later switching to dutasteride and increasing minoxidil dosage due to receding temples. They experienced shedding phases but report overall hair health improvement and no side effects from the medications.

      community Is DUT better or worse than FIN?

      in Finasteride/Dutasteride  62 upvotes 2 years ago
      The conversation discusses the effectiveness of Dutasteride (DUT) and Finasteride (FIN) for hair loss. Users share varied experiences, with some finding DUT more effective and others experiencing side effects or no change, highlighting that individual responses can vary.

      community Hydrophobic Finasteride. Why don’t we have it?

       6 upvotes 1 year ago
      The conversation discusses the potential benefits of creating a hydrophobic version of finasteride to reduce systemic side effects while maintaining scalp health. It compares this idea to fluridil, which is designed to be hydrophobic and has less systemic absorption.

      community DNA Test for better suited treatment?

       3 upvotes 11 months ago
      The conversation is about hair loss treatments, specifically discussing the use of dutasteride, minoxidil, and the potential benefits of a DNA test and PRP therapy. Opinions vary, with some users skeptical about the DNA test and PRP, suggesting sticking with current treatments.

      community Finasteride nuking 85%+ dht levels update

       25 upvotes 4 months ago
      The user discovered their previous hair loss medication was counterfeit and switched to Propecia, which significantly lowered their DHT levels. They plan to continue using Propecia and add oral Minoxidil to their routine for better results.

      community 10 months of progress on oral fin and min

       18 upvotes 1 month ago
      The user experienced significant hair regrowth on the crown after 10 months using oral minoxidil, finasteride, and biotin, with initial side effects that settled over time. They are considering whether to increase the dosage or get a transplant for further improvement.

      community 52 days since adding RU 25 mg nightly

       17 upvotes 8 months ago
      The user added RU58841 to their finasteride and minoxidil routine, noticing significant improvement in hairline after 52 days. Some users warn about potential side effects of RU58841, while others express curiosity and congratulate the progress.

      community 6 month transformation from fin to dut+min+ru

      in Progress Pictures  102 upvotes 9 months ago
      A 30-year-old male switched from finasteride to a combination of dutasteride, oral minoxidil, and RU58841, achieving significant hair growth without side effects. He plans to add GHK-Cu peptide to his regimen for further improvement.

      community Anyone tried Resveratrol, NMN, or Quercetin?

       4 upvotes 11 months ago
      Resveratrol may impair exercise benefits and isn't popular for heart health. Quercetin might reduce hair greying, while NMN is relatively new with limited information.

      community Before and after pics with Microneedling + possible confounds

       4 upvotes 5 years ago
      The user experienced hairline improvement using microneedling once a month with a 12-pin set at 1.5-2.0mm and taking Tru Niagen, alongside a heavily modified diet. They attribute the slow hairline improvement to environmental factors, particularly diet, rather than solely genetic factors.