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      community What are some topical anti androgens(not dht).

       3 upvotes 3 months ago
      The conversation is about exploring topical anti-androgens for hair loss, specifically mentioning Bicalutamide and the unpleasant smell of Spironolactone. RU58841 is unavailable, and Breezula is suggested as an alternative.

      community PP405 gets its generic name - Suvomipic

       287 upvotes 1 month ago
      Suvomipic, previously known as PP405, is progressing to Phase 3 trials for hair loss treatment. Its effectiveness compared to existing treatments like Minoxidil and Finasteride is still uncertain.

      community Hang in there buds! Showing my progress

       507 upvotes 7 months ago
      A user shared their hair regrowth progress using oral finasteride, biotin, topical minoxidil, and DS thickening shampoo over five months, reporting significant improvements in hair texture and growth. They experienced minor side effects like a slight headache from switching minoxidil forms but noted no issues with finasteride.

      community Have some questions about prescription I got from a trichologist

      in Chat  1 upvotes 1 year ago
      A trichologist prescribed Biotrade Sebomax HR Anti-Hair Loss Tonic, Spectral DNC-N Nanoxidil, Hairfollic Him/Man Vitamins, and Bosley MD DHT blocking supplements instead of finasteride due to potential risks at age 21. The user questions the legitimacy of the treatment and considers seeking a second opinion.

      community Approve PP405 quickly you coward

      in Satire  193 upvotes 1 year ago
      Pelage Pharmaceuticals is developing PP405, a topical treatment for hair growth, currently in Phase 2a trials. There is skepticism about the company's claims, and no fast-tracking approval timeline has been detailed.

      community Clascoterone study going on right now

       351 upvotes 2 years ago
      A user is participating in a phase 3 trial for Clascoterone, a topical acne medication that may stimulate hair growth, and will share results after 6 months. They will have a section of their hair shaved and marked with a tattoo for the study.

      community KX-826 users: 0.5% vs 0.9% vs foam

      in Technology  6 upvotes 1 year ago
      KX-826 is being discussed for hair loss treatment, with users debating between 0.5% and 0.9% solutions and foam. Some report side effects like headaches, while others see no changes; it blocks androgen receptors without reducing DHT levels.

      community Updates on setipiprant, bimatoprost?

       4 upvotes 10 years ago
      Setipiprant and bimatoprost are being discussed as potential future treatments for hair loss. Some individuals have started testing setipiprant before FDA approval, but no progress updates are available yet.

      community So I hacked the AAD 2026 live stream

       42 upvotes 5 months ago
      The conversation discusses a live stream presentation on Pelage PP405 for hair regrowth, with skepticism about its effectiveness compared to minoxidil. Some users express doubt and suggest sticking to proven treatments like minoxidil, finasteride, and RU58841.

      community waiting for hope DIY pp405 guy that will save us😡😡😔

      in Satire  38 upvotes 10 months ago
      People are discussing the potential of a new hair loss treatment, pp405, and its approval timeline, comparing it to existing treatments like Minoxidil and finasteride. There is skepticism about its effectiveness and concerns about the time it will take for approval and availability, especially in Europe.

      community Why are people so negative regarding Clascoterone (Breezula)?

       20 upvotes 4 months ago
      Clascoterone (Breezula) shows promising hair growth results, but skepticism remains due to past disappointments with new treatments. It may be a good alternative for those who can't tolerate finasteride or dutasteride, and can potentially be combined with them and minoxidil for better results.

      community Amplifica and AMP-303 clinical phase 1

       9 upvotes 2 years ago
      Amplifica is testing a compound called AMP-303 for hair loss, but it's not Scube3 or osteopontin. The timing for the results from the clinical trial is unknown.

      community Any chemists want to manufacture PP405 / JXL069? (Steps inside)

       89 upvotes 10 months ago
      The conversation discusses the synthesis and potential use of JXL069 and PP405 for hair loss treatment, with skepticism about their effectiveness and concerns about safety. Users mention that JXL069 has shown no results in hair growth, and there is confusion about its identity and effectiveness compared to PP405.

      community Confession/Mini-Rant: I haven’t cut my hair since I started balding

       6 upvotes 7 years ago
      The conversation discusses coping with hair loss, with the original poster using finasteride and derma rolling as treatments. They express insecurity about their appearance, choosing to grow their hair long to hide balding, while others suggest different hairstyles and self-care strategies.

      community Oral Fin+Min+Biotin Progress 2 Mo

       37 upvotes 9 months ago
      The user experienced significant hair improvement after switching from topical to oral treatments, using finasteride, minoxidil, and biotin. They reported no major side effects, except for slightly thicker hair on their hands.

      community Can I take bicalutamide for hair loss as a man, but don’t want to transition?

      in Treatment  4 upvotes 5 months ago
      A 23-year-old man with hair loss, despite using dutasteride, oral minoxidil, and RU58841, is considering bicalutamide for regrowth but is concerned about feminization. Alternatives like topical estrogen, JXL069, and spironolactone are discussed, with suggestions to explore thyroid levels and other potential underlying conditions.

      community Peptide Therapy -> GHK-CU, ZN-Thumulin, PTD-DBM

       4 upvotes 2 years ago
      The conversation is about the use of peptide therapies for hair loss, specifically GHK-CU, ZN-Thymulin, and PTD-DBM. The user is seeking feedback on the effectiveness of these treatments from those who have tried them.

      community Okay NOW it’s only three years away

       26 upvotes 9 months ago
      The conversation humorously discusses hair loss treatments, mentioning multiple hair transplants, oral minoxidil, and dutasteride, but not Breezula. It also jokes about the high cost and mild effectiveness of certain treatments.

      community ABS-201 KOL Seminar: Dr. Ralf Paus on Human Ex Vivo Hair Regrowth Data

       17 upvotes 8 months ago
      ABS-201 shows promise for male hair regrowth by blocking the prolactin receptor, with higher expected efficacy than current treatments. The discussion also covers dosing differences between macaques and humans for hmi115, highlighting a significant dosage disparity.