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Prolactin may contribute to hair loss, but targeting its receptor won't cure androgenetic alopecia. ABS-201 could be a useful alternative or adjuvant therapy, similar to JAK inhibitors, but not more effective than HMI-115.

Amplifica is developing new molecules for hair growth, with clinical trials expected soon, while Engraft Technologies is improving FUE robotic technology to make hair transplants faster and cheaper. Users express interest in the timeline for AMP-303 and concerns about high costs and effectiveness of current treatments.

A new topical compound for hair loss, claimed to be developed by Jeff Vincint, is being discussed. It reportedly doesn't use minoxidil or finasteride, and there is skepticism about its legitimacy.

The user has high DHT levels despite using dutasteride, which may not be effective due to potential damage or spoilage. They are considering a hair transplant if DHT levels don't decrease after two years.

New hair loss treatments PP405 and VDPHL01 are discussed with skepticism and hope, alongside existing treatments like minoxidil and finasteride. Users express frustration over limited progress since the 1980s but remain cautiously optimistic.

The user is using a topical spray with finasteride and minoxidil, red light therapy, and ketoconazole shampoo for hair loss, and is considering waiting a year before getting a hair transplant. Other users suggest microneedling, using oral treatments, and investing in a laser helmet for better results.

TDM-105795 is a potential hair growth stimulant that works differently from minoxidil and could be used alongside it for enhanced growth. It completed phase 2 trials in 2024, with a medium to high chance of release in 2026, but lacks recent updates or phase 3 trial information.

A 36-year-old experienced significant hair regrowth using dutasteride, oral and topical minoxidil, and keto shampoo, and plans a hair transplant for further improvement. Despite progress, they seek hairline restoration and have scheduled a transplant of 3,000 grafts.

The user has been using finasteride for six years and minoxidil for three years with no noticeable hair regrowth. Suggestions include switching to dutasteride, considering a hair transplant, and trying microneedling.

Many people feel self-conscious about hair loss during haircuts, with some using treatments like finasteride and minoxidil. Others cope by cutting their own hair or finding a trusted barber to manage thinning areas.

PP405 is a promising new hair loss treatment that may reactivate dormant hair follicles without side effects. It could surpass traditional treatments like minoxidil and finasteride if successful in further trials.

The user has been using a topical spray containing finasteride and minoxidil for six months but is experiencing increased hair shedding and concerns about its effectiveness. Suggestions include switching to oral finasteride and minoxidil, consulting a dermatologist, and checking for underlying health issues like thyroid function and nutrient deficiencies.

Hair loss treatments like finasteride and minoxidil are becoming more mainstream, with younger men starting early to prevent baldness. Increased sharing of transformations online and proactive approaches by Gen Z are contributing to noticeable changes.

The user has been using oral finasteride, minoxidil, and biotin for a year with minimal progress in hair regrowth. Many suggest a hair transplant and recommend switching to dutasteride and considering topical treatments.

The user has been using oral and topical minoxidil, finasteride, and dermarolling for two months, seeing progress with hair regrowth, especially on the temples. They also use these treatments on their beard and eyebrows with positive results.

Finasteride use resulted in increased hair growth but reduced libido for some, leading users to consider topical versions to lessen side effects. Opinions varied on the trade-off between hair benefits and sexual side effects.

A man with thick, white hair is admired for his genetics, leading to discussions about hair loss and the preference for white hair over balding. Some speculate about the use of treatments like finasteride.

Hair regrowth can start as thin hairs that may thicken over time, with treatments like finasteride and minoxidil showing varied results. Some users report initial shedding followed by thicker regrowth, while others experience mixed outcomes in different areas.

GT20029 is a topical treatment that degrades androgen receptors to prevent hair thinning and loss, potentially offering fewer side effects than systemic treatments like finasteride. Concerns include its impact on hair texture and potential systemic effects, with market availability speculated in 3 to 5 years.

A long-term finasteride user experienced side effects like sexual dysfunction, dry eyes, muscle weakness, and brain fog, which improved when they stopped the medication. They decided to stop finasteride again, questioning if maintaining hair was worth the negative impact on their well-being.

PP405 is discussed as a potential hair growth stimulant, possibly more effective than minoxidil, but not a cure for hair loss. There is skepticism about its ability to regrow "deadzones," and concerns about its impact on those with hair transplants.

There is concern about a potential ban on finasteride in the EU, but many believe it is unlikely unless serious side effects are found. Users rely on finasteride for hair loss and other health benefits, and a petition has been created to oppose any restrictions.

A user has been treating hair loss for a year with Finasteride, oral Minoxidil, microneedling, and ketoconazole shampoo, recently adding Dutasteride. They are unsure about the effectiveness and seek advice on whether to continue or switch fully to Dutasteride.

A user is considering using verteporfin with microneedling, oral/topical minoxidil, and RU58841 to treat hair loss. They seek advice on dosage and application methods.

The conversation discusses whether finasteride's reduction of DHT and increase in scalp testosterone contribute to hair follicle miniaturization. Some participants argue testosterone does not cause miniaturization, while others suggest that even with reduced DHT, other androgens like testosterone may still contribute to hair loss.

Sugary beverages increase the risk of pattern hair loss in men by 57%, and type 2 diabetes is linked to female pattern hair loss. Reducing sugar intake and using treatments like finasteride and minoxidil may help manage hair loss.

Quercetin and houttuynia cordata extract may stimulate hair growth by enhancing cellular energy metabolism and increasing growth factor secretion. Quercetin has low oral bioavailability, and its natural tint might stain the scalp if used topically.

Aminexil/Kopexil may help reduce hair loss by addressing perifollicular fibrosis in androgenetic alopecia, but it lacks the extensive clinical backing of finasteride and minoxidil. Some users find it effective, but availability and cost are issues, especially in the US where it's not FDA-approved.

A 19-year-old experiencing mild hair loss plans to start finasteride and use Nizoral, avoiding minoxidil for now. Others share their experiences with finasteride, noting minimal side effects and advising against worrying about potential negative effects.

The user has been using topical minoxidil for over 6 months and topical finasteride for 3 months without seeing significant progress and is considering stopping minoxidil. Other users suggest continuing the treatment for a longer period, as progress can take time, and recommend considering oral versions for potentially better results.