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30-60 / 1000+ resultscommunity A concern regarding the upcoming androgen degrader drug GT20029
GT20029 is a topical treatment that degrades androgen receptors to prevent hair thinning and loss, potentially offering fewer side effects than systemic treatments like finasteride. Concerns include its impact on hair texture and potential systemic effects, with market availability speculated in 3 to 5 years.
community Feeling pretty hopeless... Dry skin and eczema causing my alopecia.
The user has been using dutasteride, lymecycline, betamethasone, and minoxidil for hair loss but struggles with eczema and dry skin. They feel hopeless as no treatments or moisturizers have helped, and they are concerned about their appearance due to their soft facial features.
community Dutasteride Mesotherapy with 1mm dermaroller - how much pressure?
The conversation discusses using a 1mm dermaroller with varying pressure for Dutasteride Mesotherapy and the effectiveness of topical dutasteride combined with microneedling. There is debate over whether this method qualifies as mesotherapy, with some suggesting it is more accurately described as "mesotherapy adjacent."
community New topical claims complete reversal of AGA in 3 months
A new topical treatment called RT1640 claims to reverse AGA using cyclosporine A, Minoxidil, and a new chemical entity, RT175. Users are skeptical due to lack of clinical trial data and inconsistent before-and-after photos.
community 1.5 years on dutasteride and on and off microneedling
The user experienced hair regrowth using dutasteride daily, microneedling weekly, and Nizoral shampoo, after stopping minoxidil due to side effects. They also use a mix of pumpkin seed, rosemary, and peppermint oil, and are considering RU58841 for more temple area thickness.
community Microneedling with Verteporfin
community Dermastamp vs Dermaroller vs Dermapen
Dermastamp is preferred for hair growth and skin health due to fewer scars, with recommended needle sizes of 0.5-1.5mm. Dermapen is also favored over dermarollers, which are considered dangerous.
community Metal particles abraded from dermapen (or dermaroller) needles. Is it possible?
Concerns about metal particles from dermapen or dermaroller needles potentially entering the skin and lymph nodes, similar to tattoo needles. Discussion includes the possibility of using Minoxidil, finasteride, and RU58841 for hair loss treatment.
community 27M microneedle+ oral .5 dut 2.5 min daily
The user has been using microneedling, oral dutasteride, and minoxidil daily for 1.5 years with little change in hair loss, possibly stabilizing it. Concerns about the effectiveness and side effects of topical treatments and oral anti-androgens were discussed.
community Growth factors, VEGF, And more,possible permanent cure for people with moderate hairloss?
The user discusses using dutasteride to stop hair loss and bimatoprost for regrowth. They plan to use VEGF with hydrogels for potentially permanent hair follicle improvement and suggest PRP as an alternative.
community GT20029 & KX826 Major Updates from Kintor.
KX826 shows promise as a hair loss treatment with a 10% increase in hair count, but concerns about Kintor's marketing practices and the systemic effects of treatments like GT20029 and RU58841 remain. Users express skepticism and hope, with some preferring traditional treatments like finasteride and minoxidil.
community Kintor develop GT20026 Anti-Androgen receptor drug with NO SIDES
The conversation discusses GT20029, a new topical drug for hair loss and acne without notable side effects, which has been accepted for investigational use in China. Some users express skepticism about the legitimacy of the company and the potential for other drugs like RU58841 to be developed due to patent expiration and lack of profitability.
community Kartogenin for hair growth? Would it work?
Kartogenin is being discussed as a potential topical treatment for hair growth. The conversation humorously notes its testing on animals like mice and rabbits.
community Topical rapamycin, metformin, a-kg grow hair
The conversation discusses the potential of topical rapamycin, metformin, and alpha-ketoglutarate (a-KG) for hair growth, with skepticism expressed about their effectiveness based on personal experience and existing use. It also mentions AICAR, known as cardarine or GW, which is not suitable for long-term use due to cancer risks in animal studies and its similarity to metformin.
community Verteporfin being used anywhere?
Verteporfin is being explored for hair regeneration, with unofficial trials and updates shared online. Efforts are being made to encourage more surgeons to trial verteporfin for donor hair regeneration.
community Inflammation's surprising role in shrinking hair follicles and AGA
Inflammation plays a significant role in hair follicle miniaturization and androgenetic alopecia, with treatments like ketoconazole shampoo, minoxidil, and finasteride being used to address it. Users discuss the benefits of anti-inflammatory treatments and peptides like KPV, alongside traditional hair loss treatments, to improve scalp health and hair quality.
community Meta analysis: Topical or mesotherapy dutasteride is more effective than topical finasteride in the treatment of AGA in men
Topical Dutasteride is more effective than topical Finasteride for treating AGA in men, with fewer side effects. Mesotherapy with Dutasteride, administered every 3 months, shows promising results for hair regrowth and maintenance without daily routines or significant side effects.
community Epibiotech will now offer off-the-shelf allogeneic hair multiplication treatment in South Korea
Epibiotech will offer off-the-shelf allogeneic hair multiplication treatment in South Korea, using dermal papilla cells from donors to grow hair in balding areas. This method is cheaper and less invasive than traditional hair transplants.
community Topical Dutasteride and Mesotherapy Dutasteride: It Works
Topical dutasteride with microneedling and mesotherapy dutasteride injections are effective treatments for androgenetic alopecia in both men and women. These methods offer promising alternatives to oral therapies with potentially fewer systemic side effects.
community I interviewed Kintor: GT20029 Clinical Trial Pictures. As well as KX826.
GT20029 and KX826 are promising hair loss treatments, with GT20029 increasing hair count and KX826 showing significant results. KX826 may be a good alternative for those who can't use finasteride or dutasteride, though results vary.
community Targeting multiple AGA mechanisms with commonly available substances
The conversation discusses using a multimodal approach to treat androgenic alopecia, including substances like gamma-linolenic acid, DHA, sulforaphane, melatonin, cetirizine, astaxanthin, fisetin, apigenin, curcumin, limonene, genistein, and berberine. Users also mention using ketoconazole, minoxidil, and low-level laser therapy (LLLT) as part of their hair loss treatment regimens.
community Read about a recent study on the effects of Agerarin on ex-vivo hair bulbs and...
The user started using Agerin cream on their scalp and noticed some hair growth, despite not applying it consistently. They also use Minoxidil, RU58841, dutasteride, and finasteride, and have seborrheic dermatitis.
community Kintor Pharma Announces Positive Top-line U.S. Phase I Trial Results of GT20029, the World’s First Topical Use PROTAC Compound
The conversation discusses positive initial trial results for GT20029, a topical compound for hair loss that degrades androgen receptors, potentially requiring only weekly application. Participants express hope for this treatment to be more effective and convenient than current options like Minoxidil, Finasteride, and RU58841.
community Dr. Bloxham Final verteporfin update
Verteporfin is being explored for its potential to improve hair transplant outcomes by reducing scarring and increasing donor hair follicles. There is skepticism about the results, with some claiming misleading presentation of evidence.
community GT20029 Anageninc Market Availability
The conversation discusses the potential market release of a hair loss treatment called GT20029 by Anageninc, with users expressing interest and discussing the importance of safety and effectiveness. Some users plan to contact Anageninc to show demand for the product.
community Mesotherapy Dutasteride for Androgenetic Alopecia
Mesotherapy with dutasteride is suggested as an effective alternative for those experiencing side effects from oral treatments, as it targets hair follicles directly. While oral treatments are more proven, mesotherapy may offer better localized results without systemic exposure.
community Anyone use a custom topical from Skin Medicinals with latanoprost ?
The conversation discusses using a custom topical from Skin Medicinals containing latanoprost for hair loss, which helps move hairs into the anagen phase. The user is curious about the cost and effectiveness of this treatment.
community Got my Oleic fatty acid they used in Korean study. Fuck you mice!
Oleic acid and microneedling are being explored for hair regrowth, but results are mixed. Addressing DHT and fibrosis is crucial, with treatments like finasteride, minoxidil, and scalp massage also discussed.
community No need to microneedle / dermastamp , if using tretinoin or tazarotene ?
Using tretinoin or tazarotene with minoxidil may eliminate the need for microneedling or dermastamping. Microneedling can enhance minoxidil's effects but may cause long-term scalp issues.