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      community Derms are so useless, how did they even get to be in these positions with all these academic years when random internet dwellers know more than them?

      in Chat  101 upvotes 2 years ago
      The conversation is about frustration with dermatologists not effectively treating hair loss and the difficulty in obtaining prescriptions for Minoxidil and Finasteride. Some users suggest seeing specialists or general practitioners for hair loss treatment, while others share their own experiences with dermatologists and the importance of doing personal research.

      community Hair Remedies that Don't Work for Anybody Seeking Hair Regrowth

      in Treatment  6 upvotes 4 years ago
      Hair loss treatments discussed include minoxidil, finasteride, and RU58841. Salon products and supplements generally don't work for hair regrowth unless there's a severe nutritional deficiency, while hormonal treatments like estrogen and spironolactone can be effective.

      community Having androgen receptor density and sensitivity at wrong f*ing place

      in Satire  7 upvotes 2 months ago
      The conversation discusses hair loss treatments, focusing on the use of topical minoxidil, microneedling, finasteride, and dutasteride, while debating the role of testosterone and DHT in hair loss. It also touches on the potential liver health impacts of these treatments and the genetic sensitivity of hair follicles to androgens.
      FCE 28260: A Forgotten 5α-Reductase Inhibitor

      community FCE 28260: A Forgotten 5α-Reductase Inhibitor

      in Research  330 upvotes 4 months ago
      FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.

      community Fuzzy Feeling To Scalp?

      in General  58 upvotes 3 weeks ago
      The user has been taking oral finasteride for 2 months, experiencing more hair loss but noticing some fuzzy hair growth on the scalp. They are questioning if this new hair growth is significant.
      Can I Start Hair Regrowth Treatments at 30? Looking for Recommendations!

      community Can I Start Hair Regrowth Treatments at 30? Looking for Recommendations!

      in General  119 upvotes 1 month ago
      A 30-year-old is considering starting hair regrowth treatments and is seeking advice on medications like minoxidil and finasteride, as well as other therapies. Users suggest starting with the "big 4" treatments and share that many have seen success even when starting later in life.
      Is this a male pattern baldness or diffuse baldness?

      community Is this a male pattern baldness or diffuse baldness?

      in General  144 upvotes 4 months ago
      A 23-year-old male experienced sudden hair loss over six months, losing about 30% of his hair. Treatments include 10% minoxidil, a hair spray, and a vitamin pill; opinions on the cause vary between normal hair loss due to deficiencies and male pattern baldness.

      community Should I start minoxidil before finasteride?

      in Treatment  3 upvotes 1 year ago
      A 21-year-old male from Bangladesh is experiencing hair loss and was advised by a dermatologist to use ketoconazole shampoo, anti-fungal treatments, biotin, and 5% minoxidil, with finasteride to be considered after six months. The user is unsure whether to follow this advice or start finasteride immediately alongside minoxidil.

      community Ru-58841 vs KX-826/pyrilutamide while on steroids

      in Finasteride/Dutasteride  3 upvotes 1 month ago
      The user increased their steroid dosage and noticed hair shedding, so they adjusted their regimen by reducing steroid doses and adding oral dutasteride. They are also experimenting with combining RU-58841 and KX-826/pyrilutamide in minoxidil to address hair loss.

      community DHT/Testosterone levels in scalp Fin VS Dut.

      in Finasteride/Dutasteride  60 upvotes 5 months ago
      Dutasteride raises scalp testosterone by 99%, which may not be ideal for those sensitive to all androgens. Some argue finasteride's balancing act might be better, while others believe dutasteride is superior for hair regrowth.

      community Homemade topical spironolactone

      in Research/Science  25 upvotes 2 years ago
      The potential effectiveness of homemade topical spironolactone in treating hair loss, with studies suggesting it is more effective than finasteride and even minoxidil when used as monotherapy. The conversation also mentions that other anti-androgens are being developed which may soon hit the market.

      community Best Shampoo Recommendations!!

      in Product  12 upvotes 6 months ago
      A user is seeking shampoo recommendations for thinning hair that doesn't cause dryness or brittleness. Another user suggests Pura D'or, noting it makes their hair feel better despite thinning, but mentions no shampoo will help with hair loss.

      community Started war against AGA, who’s gonna win ?

      in Minoxidil  123 upvotes 1 month ago
      The conversation discusses various treatments for hair loss, including minoxidil, finasteride, and topical dutasteride, with users debating their effectiveness and side effects. Despite the treatments, many believe androgenetic alopecia (AGA) ultimately prevails in the long term.

      community 16 months finasteride & minoxidil progress

      in Progress Pictures  605 upvotes 5 months ago
      User shared 16-month progress using finasteride 1 mg/day and minoxidil 5% solution once/day, noting significant regrowth, especially in temporal peaks. Users discussed shedding, side effects, and positive feedback from others.

      community Mechanism of action of alfatradiol (17 alpha estradiol)

      in Research/Science  6 upvotes 6 months ago
      The conversation discusses the mechanism of action of alfatradiol (17 alpha estradiol) in treating hair loss. It explores theories that it either inhibits 5 alpha reductase to prevent T->DHT conversion or aromatizes scalp T into 17-alpha-estradiol to save hair.

      community 3 months min 5 % hairline is progressing

      in Progress Pictures  93 upvotes 1 year ago
      The post discusses the user's hair loss treatment involving daily use of 5% minoxidil, rosemary oil 2-3 times a week, derma-rolling twice a week, and daily vitamin D. A reply suggests the user to start using finasteride before hair falls out.

      community CB-03-01 supposed hair loss cure

      in Treatment  7 upvotes 3 years ago
      The conversation discusses why CB-03-01, a potential hair loss treatment, isn't widely discussed despite evidence of its effectiveness and safety. Some users mention other treatments like melatonin, procianidin b2, and RU58841, debating their effectiveness and safety.

      community 21M, Dermatologist prescribed only Minoxidil

      in Minoxidil  7 upvotes 3 months ago
      A 21-year-old was diagnosed with early-stage androgenetic alopecia and prescribed only minoxidil 5% and ketoconazole shampoo by a dermatologist, who advised against finasteride for now. The user is skeptical about starting minoxidil due to concerns about increased hair loss.

      community My dermatologist screwed me over methinks (18M)

      in Minoxidil  12 upvotes 5 months ago
      A user discusses their hair thinning journey, starting minoxidil at 16, switching treatments, and experiencing significant shedding after resuming minoxidil. They are now using minoxidil daily and considering PRP if shedding continues, while also planning lifestyle changes to improve their condition.