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      community Combining Microneedling with LLLT

       14 upvotes 1 year ago
      Combining microneedling with Low Level Laser Therapy (LLLT) for hair growth, with discussions on device legitimacy and effectiveness. Alternatives like PEMF and the use of oral and topical treatments such as dutasteride, minoxidil, and finasteride are also considered.

      community Is this Progress? - NW7 Diffuse going for the comeback. (49M)

       32 upvotes 6 months ago
      A 49-year-old is using finasteride, minoxidil, tretinoin, and ketoconazole shampoo to combat advanced hair loss and hopes for enough regrowth to consider a hair transplant. Progress is slow, but some improvement is noted by others.

      community Making my own topical finasteride - ethanol question

       4 upvotes 3 years ago
      The conversation is about making topical finasteride using ethanol. The user is advised to use non-denatured or food-grade ethanol, as denatured ethanol may be harmful with prolonged skin exposure.

      community I hope ET-02 or PP405 will be released in the next 4-5 years

       18 upvotes 1 year ago
      PP405 is a potential hair loss treatment that may work by blocking signals that cause hair cells to stop growing, requiring daily application for effectiveness. It could serve as an alternative to minoxidil and finasteride, but it is not yet available on the market and may take several years to be released.

      community Is PP405 actually different, or does it fall into the same pattern as previous treatments?

      6 months ago
      PP405 is being discussed as a potential new approach to hair loss by targeting follicle stem cells, suggesting a different mechanism from existing treatments like finasteride and minoxidil. However, there is skepticism about whether it will lead to meaningful long-term outcomes or follow the pattern of previous treatments that showed promise but lacked consistent results.

      community It's probably RU58841, which is weak in adenosine.

       16 upvotes 2 years ago
      The conversation is about using adenosine, finasteride, and minoxidil for hair loss treatment. The user ordered a 0.75% adenosine solution and is currently using finasteride 1mg and minoxidil 5%.

      community Ordered PTD-DBM from tailor made

       6 upvotes 5 years ago
      The conversation discusses hair loss treatments, including finasteride, microneedling, minoxidil, and PTD-DBM. The user has not noticed significant regrowth and is considering cost-effective options like valproic acid.

      community 3 month Update 1mg Fin and monoxidl

      in Progress Pictures  23 upvotes 2 months ago
      The user shared a 3-month update on using 1 mg finasteride daily, minoxidil foam twice daily, derma stamping weekly, and ketoconazole shampoo twice weekly for hair loss. They are considering adding tretinoin cream and mentioned a possible future hair transplant.

      community Phase 3 Study for PP405 officially posted

       43 upvotes 3 days ago
      PP405 is in a phase 3 trial for hair loss treatment, with the study expected to run until June 2028. Minoxidil and finasteride remain key treatments, with hopes for PP405 to offer a new mechanism of action.

      community 20M, 2.5 months, 1mg fin, topical min(local)

      in Progress Pictures  125 upvotes 1 year ago
      A 20-year-old male shares his 2.5-month progress using 1mg finasteride, topical minoxidil, tretinoin, dermarolling, and ketoconazole for hair loss, noting slight libido decrease. Users discuss sourcing topical finasteride and request more photos to see the results.

      community Any good place to buy KX-826, AHK‑Cu and PTD-DBM?

       1 upvotes 5 months ago
      The conversation discusses purchasing experimental hair loss treatments KX-826, AHK-Cu, and PTD-DBM, with the user already using Minoxidil and having side effects from Finasteride. Concerns about the legitimacy of certain suppliers and the authenticity of products like pp405 are also mentioned.

      community Anyone Taking Finasteride and Creatine?

       7 upvotes 5 years ago
      The conversation discusses concerns about taking finasteride and creatine together due to potential DHT increase from creatine, which might counteract finasteride's effects. Some users believe the DHT increase from creatine is negligible, while others advise caution.

      community Eucapil, Fluridil update from manufacturer

       4 upvotes 1 year ago
      The user is experiencing hair loss after a hair transplant and is considering using fluridil (Eucapil) and possibly alfatradiol as treatments, as they couldn't tolerate finasteride or minoxidil. The manufacturer of Eucapil confirmed they won't produce higher concentrations due to lack of efficacy.

      community Whats the deal with TDM-105795?

      in Research/Science  4 upvotes 6 months ago
      TDM-105795 is a potential hair growth stimulant that works differently from minoxidil and could be used alongside it for enhanced growth. It completed phase 2 trials in 2024, with a medium to high chance of release in 2026, but lacks recent updates or phase 3 trial information.

      community 18mo progress - topical fin/min + oral min/dut

      in Progress Pictures  91 upvotes 1 year ago
      The user experienced significant hair regrowth using topical finasteride/minoxidil and oral minoxidil/dutasteride, with some mild side effects that diminished over time. They plan to add microneedling to their regimen and have seen hair shedding cycles every six months, followed by thicker regrowth.

      community When should we get the next news about PP405

       24 upvotes 10 months ago
      Results for PP405 are expected next year, with concerns about its pricing and potential black market availability. Some users believe it may be slightly more effective than finasteride and dutasteride, and combining it with treatments like minoxidil and microneedling could be beneficial.

      community M18 - 7 Months on topical fin + min Not working for me

      in Finasteride/Dutasteride  92 upvotes 1 year ago
      Topical finasteride and minoxidil are not effective for the user, who is considering switching to oral treatments like finasteride or dutasteride. Many suggest oral medications are more effective, and some recommend additional treatments like microneedling and other topical solutions.

      community I think microneedling before topical application of finasteride (or dut) is a path we should investigate (for those of us who don't care about systemic absorption). Here's why...

       20 upvotes 1 year ago
      Microneedling before applying topical finasteride or dutasteride may enhance their effectiveness by increasing local absorption in the scalp, despite concerns about systemic absorption. Users discuss combining this method with oral treatments and minoxidil, noting potential benefits and side effects.

      community PP405 Hair Loss Drug: Phase 1 Human Results & Biopsy Insights

       213 upvotes 1 year ago
      PP405 is a potential hair loss treatment undergoing trials, with discussions on its effectiveness and comparison to existing treatments like finasteride and minoxidil. There is skepticism about its status as a cure, with hopes for future advancements in genetic treatments like CRISPR.

      community The final nail in the coffin. PP405 is confirmed JXL069.

       440 upvotes 1 month ago
      PP405 and JXL069 are confirmed to be the same molecule, leading to disappointment due to poor hair regrowth results. Users express skepticism about the credibility of Pelage and the effectiveness of JXL069.

      community Sprinkle that PP405 on my scalp like I sprinkle salt on my stake

       119 upvotes 1 year ago
      PP405 shows promise for hair growth with significant results after 4 weeks, but skepticism exists due to its unavailability. Some users are hopeful for its potential, while others express concerns about side effects and market release delays.