Topical 2-deoxy-D-ribose (2dDR) regrows hair in mice almost as well as 2% Minoxidil. However, 2dDR may contribute to oxidative stress and hair loss due to the formation of advancedglycation end products (AGEs).
A user is treating hair loss with Dutasteride, Minoxidil, RU58841, Derminator 2, Vitamin D, Biotin, and Zinc. After 6 months, there's no significant visual improvement, but the user feels less insecure about Retrograde Alopecia.
User starts Nuclear Stack treatment for hair loss, including Dutasteride, Minoxidil, RU58841, Derminator 2, and supplements. Seeks advice on storing and dosing RU58841.
Calecim (PTT-6) Advanced Hair System is a 6-week hair restoration product using stem cell-derived ingredients to stimulate hair growth. Users are skeptical, calling it overpriced and ineffective, suggesting alternatives like LLLT devices or PRP treatments.
A user shared their 5-month hair loss treatment progress, using 1mg finasteride, daily GHK-CU injections, keratin/biotin/MSM supplements, Pura D’Or shampoo and conditioner, Ayurvedic oil, ketoconazole thrice weekly, and weekly microneedling with topical GHK-CU. The post includes progress pictures.
The conversation is about people with advanced hair loss (Norwood 6 or 7) who have seen significant hair regrowth using treatments like finasteride, minoxidil, microneedling, and RU58841. Nine cases were collected to motivate others to try these treatments despite advanced hair loss.
A user is treating their advanced hair loss with a regimen including topical finasteride, minoxidil, hydrocortisone, stem cell serum, peptide serum, multivitamins, he shou wu tea, derma pen, argan oil, and a derma roller. Replies suggest it's too early to judge progress and recommend staying consistent, with one suggesting oral minoxidil as an additional option.
The conversation discusses using oral minoxidil for advanced hair loss and whether it's safe to consume energy drinks while on this medication. It also questions the benefits of combining microneedling and tretinoin with oral minoxidil treatment.
The conversation discusses various hair loss treatments, highlighting Advanced Trichology Topical Melatonin Hair Growth Serum, hers Minoxidil Foam, Keranique Hair Regrowth Treatment, Nioxin 5% Minoxidil, Virtue Minoxidil 5%, and Rogaine Women's 2% Minoxidil. One user suggests that the list may be influenced by sponsorship and emphasizes that minoxidil is commonly recommended but doesn't address the root cause of hair loss like finasteride or dutasteride.
Minoxidil 0.5% MMP® showed better results in parietal-vertex regions for less advanced female pattern hair loss compared to Minoxidil 5%. MMP® with Minoxidil can improve the quality of life for these patients.
The user is trying alternative hair loss treatments like caffeine shampoo and dermarolling before considering minoxidil or other advanced treatments, and has noticed an increase in vellus hairs and some strong terminal hairs after two months of daily caffeine shampoo use. They plan to continue the treatment and document progress.
Dutasteride is generally considered more effective than finasteride for hair regrowth and thickening, despite some negative anecdotal reports. Users report thicker hair and better skin with dutasteride, and some believe negative reviews are due to advanced alopecia or impatience with the shedding process.
The post discusses the potential of upregulating aromatase to treat hair loss, suggesting that increasing CCL2 levels through Vitamin D or microneedling might help. The user questions why microneedling doesn't work for everyone, especially those with advanced hair loss.
FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.
The user underwent two FUT hair transplant surgeries with subpar results, leading to disappointment and continued use of Minoxidil, laser cap, dermaroll, and biotin. They advise thorough research before committing to hair transplants, especially for those with advanced hair loss.
User considers trying AAPE for hair restoration, costing $700 for 6 months. Others discuss its potential effectiveness and mention a study with promising results.
The conversation is about a user starting a hair loss treatment with Dutasteride, Minoxidil, and RU58841, hoping to prevent baldness. Other users comment on the user's current hair condition and the intensity of the chosen treatment.
The conversation discusses the lack of significant advancements in hair loss treatments beyond finasteride and minoxidil, questioning if hair restoration technology has reached a dead end. Hair transplant technology has improved, but new medications face challenges with market entry, cost, accessibility, and long-term effectiveness.
A user has been using Minoxidil and dermarolling for 4 months to treat hair loss, with some success. However, others suggest that without adding finasteride to the regimen, the hair regrowth may not last.
KX-826 Pyrilutamide 1% is launching soon, and users are discussing its potential benefits and drawbacks compared to other treatments like Minoxidil and finasteride. Some users are skeptical about its effectiveness, while others are hopeful it will be a safer alternative.
A user shared their 9-month progress using Minoxidil, Finasteride, microneedling, and Nizoral shampoo for hair loss, expressing great satisfaction with the results. They use a Min/Fin topical spray nightly, Minoxidil in the morning, microneedle twice a week, and Nizoral shampoo twice a week.
A user underwent a second hair transplant for increased density and to address hair loss in the crown area, with 3,800 grafts at a cost of 2,200 euros at Estepalace, including additional services. Some commenters discussed the appearance of the hairline and the importance of using DHT blockers like finasteride or dutasteride post-transplant.
The conversation discusses the effects of finasteride on hair loss and its potential neurological and sexual side effects. Users share personal experiences, with some reporting positive outcomes and others expressing concerns about cognitive function.
The user underwent a hair transplant with 3500 grafts and has been using Finasteride and Minoxidil for 5.5 months, seeing some growth. They plan to have a second transplant for the crown area and are seeking opinions on future results and density improvement.
The conversation jokes about whether the character Vegeta from Dragon Ball should use hair loss treatments like finasteride or minoxidil. Some suggest he doesn't need it as his hairline hasn't changed for years, while others humorously propose treatments or question his hair genetics.
A 26-year-old male shared progress pictures after 4 months of treating hair loss with finasteride (1.25 mg on Mondays, Wednesdays, and Fridays), topical minoxidil twice daily, ketoconazole shampoo twice weekly, and weekly microneedling at 1.5 mm. He is seeing hair growth improvement, especially in the front, and is considering hair grafts for the crown area if necessary for more density.
The conversation discusses using finasteride topically for hair loss and concerns about potential side effects like feminization and impact on muscle growth. One person shared their experience with finasteride, indicating it increased testosterone and did not prevent them from gaining muscle or strength.
The user shared their 8-month hair transplant results from Cosmedica, involving around 3800 grafts and topical use of Minoxidil and Finasteride since the operation. They discussed the procedure details, cost, and the possibility of a second operation for crown and touch-ups.
