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      community Does Tretinoin work? Can somebody share their experience

       2 upvotes 7 months ago
      Tretinoin can increase hair follicles and is used alongside minoxidil and finasteride for hair growth, though it may cause skin peeling. Users report varying results, with some experiencing regrowth and others questioning its efficacy for hair.

      community South Korea is debating whether hair loss should be covered by public healthcare. That alone says a lot about how we still misunderstand hair loss.

       67 upvotes 7 months ago
      South Korea is debating whether hair loss treatments should be covered by public healthcare, highlighting the issue's impact on mental health and social functioning. The discussion centers on whether hair loss should be classified as a medical condition rather than a cosmetic issue, considering its psychological effects and the biological processes involved.

      community Clascoterone 5% Delivers Strong Phase 3 Hair-Growth Results

       371 upvotes 8 months ago
      Clascoterone 5% solution shows strong potential for hair growth, offering a new treatment for alopecia with minimal side effects. It blocks androgen receptors locally and may be available by late 2026 or early 2027.

      community Shedding increase from pumpkin seed oil - dread shed or time to stop?

      in Female 8 months ago
      A user experienced increased hair shedding after taking pumpkin seed oil for 4 weeks and is unsure if it's a "dread shed" or if the oil isn't suitable. They cannot tolerate anti-androgens like spironolactone and finasteride due to side effects and are seeking advice on whether to continue with pumpkin seed oil.

      community It is what it is with some people

      in Satire  162 upvotes 8 months ago
      Hair loss treatments like finasteride and dutasteride are discussed, with concerns about side effects such as depression and brain fog. Some users argue about the necessity and impact of DHT on libido and other bodily functions.

      community (MTF 35) Results of 18 Months of HRT

       775 upvotes 8 months ago
      A transgender woman experienced significant hair regrowth after 18 months of hormone replacement therapy (HRT) with estrogen and bicalutamide. The discussion notes HRT's effectiveness for hair regrowth but warns against its use for cisgender men due to feminizing effects.

      community The expected timeline for PP405 - Next update at AAD Annual Meeting in March 2026 ?

       34 upvotes 8 months ago
      A new hair loss treatment, PP405, showed promising Phase 2a results with 31% of patients experiencing over 20% hair density increase without systemic absorption, avoiding hormonal side effects. The treatment is expected to be expensive, with Phase 3 trials starting mid-2026, and there is skepticism about the data's strength.

      community How safe and/or difficult would it theoretically be to turn raw 99.9% clascoterone into topical formula?

       6 upvotes 9 months ago
      The user discusses their hair regrowth success with minoxidil, red light therapy, massage, and derma stamping but expresses concerns about using finasteride due to potential side effects. They are interested in using clascoterone as a topical treatment for hair loss and are exploring the possibility of creating a topical formula from raw clascoterone powder.

      community White hair seemed to be turn black, re-pigmentation

       1 upvotes 10 months ago
      The user experienced hair repigmentation and attributes improvements in hair and overall health to a carnivore diet, Boron, and Selenium supplementation. They stopped using finasteride after 20 years, noticed increased testosterone and libido, and observed hair regrowth with RU58841.

      community Hair loss research is a money grab

       227 upvotes 10 months ago
      Hair loss is linked to DHT, with treatments like finasteride and minoxidil being common but not definitive. Economic interests influence research, and there is potential for new treatments like PP405 and RU58841.

      community Do mens shampoo for hair loss help with balding?

      in Research/Science  44 upvotes 10 months ago
      Shampoos, including those with ketoconazole, may offer mild benefits for hair health but are not effective for stopping hair loss or balding. Effective treatments for hair loss include finasteride and minoxidil, often used together, while shampoos are generally not on the scalp long enough to impact hair follicles significantly.

      community Dut 0.5mg ED and oral min 3mg ED 5 months progress

      in Progress Pictures  28 upvotes 10 months ago
      The user is using 0.5mg dutasteride daily and 3mg oral minoxidil daily for hair loss, but hasn't seen improvements after five months. They report miniaturization and thinning, especially at the hairline and crown, and are advised to wait at least a year for better results.

      community I was wrong about Dutastride. Let the I told you so comments rain in.

       76 upvotes 10 months ago
      Switching from dutasteride to finasteride caused increased hair loss, dandruff, depression, and erectile dysfunction. The user plans to return to dutasteride, possibly with minoxidil, and is considering dosing strategies to manage side effects and regrowth.

      community Any help with female hair loss?

       2 upvotes 10 months ago
      A 20-year-old female with PCOS is experiencing hair loss and excessive facial hair. She is using ketoconazole and caffeine shampoos, microneedling, and considering anti-androgens like finasteride, but is cautious about minoxidil due to facial hair concerns.

      community Popular hair loss drug linked to higher suicide risk: compared to non-users, finasteride (Proscar/ Propecia) users have a markedly increased risk of depression, anxiety, and suicidal thoughts. Over 30 years of observation, 19,320 suicides were expected.

       494 upvotes 11 months ago
      Finasteride users may have an increased risk of depression, anxiety, and suicidal thoughts, though some attribute these issues to hair loss itself. The link between finasteride and mental health effects is debated, with varying user experiences.

      community 5 months on dut/fin/min progress

      in Progress Pictures  175 upvotes 11 months ago
      The user experienced significant hair regrowth after 5 months using finasteride, dutasteride, and oral minoxidil, despite initial side effects like erectile dysfunction, which resolved after switching from finasteride to dutasteride. The user reports full recovery of hair density and improved skin condition, though the right temple remains slightly recessed.

      community One year 2.5mg Minoxidil 1.25mg finasteride

      in Progress Pictures  185 upvotes 1 year ago
      A user shared progress pictures after one year of using 2.5mg Minoxidil and 1.25mg Finasteride for hair loss. The discussion includes suggestions for additional treatments like dermastamping, dutasteride, and increasing Minoxidil dosage, with mixed opinions on the effectiveness of current treatments.

      community Finasteride and “anti-aging” effects

      in Treatment  218 upvotes 1 year ago
      Finasteride may help users look younger by suppressing DHT, affecting skin and hair. Users also emphasize skincare, sunscreen, and lifestyle for maintaining a youthful appearance.

      community How to take care of the microneedler?

      in Microneedling  7 upvotes 1 year ago
      Disinfecting microneedlers is important to prevent infection, with suggestions to use high-percentage alcohol or denture tablets for sterilization. Rollers may cause skin damage, so stamps or pens are recommended for safer microneedling.

      community The homeless crackhead protocol

       4487 upvotes 1 year ago
      The conversation humorously suggests that drug use might be more effective for hair retention than traditional treatments like minoxidil or finasteride. It attributes full heads of hair in homeless individuals to lifestyle factors like reduced stress or hormonal changes.

      community Nizoral absolutely fucked up my hair

      in Ketoconazole  88 upvotes 1 year ago
      Nizoral shampoo caused significant hair thinning and oiliness for some users, while others found it beneficial for slowing hair loss. The original poster experienced negative effects and was advised to stop using Nizoral and switch to a gentler shampoo.

      community I'm becoming non-responder to minoxidil. What's going on?

       7 upvotes 1 year ago
      The user experienced reduced effectiveness of minoxidil after consistent use, despite using dutasteride to maintain hair. They are considering alternatives like microneedling and exploring options like hair transplants due to dissatisfaction with current hair density.

      community What is the ultimate hair regrowth protocol

       29 upvotes 1 year ago
      The conversation covers aggressive hair regrowth treatments like Dutasteride, Minoxidil (oral and topical), RU58841, microneedling, and ketoconazole shampoo. It also mentions PRP, laser therapy, GHK-Cu injections, and hormone therapy for maximum regrowth.

      community Are any of you using topical spironolactone ?

      in Treatment  4 upvotes 1 year ago
      The user is using topical dutasteride, minoxidil, and spironolactone for hair loss, with positive results after adding spironolactone. Another user takes oral spironolactone, dutasteride, and finasteride, noting decreased libido but no major side effects.

      community Min and Fin User: Nutrition and how do you all track?

       1 upvotes 1 year ago
      The user started using topical Minoxidil and Procapil, then added oral Minoxidil and Finasteride, seeing some hair thickening but no improvement in the frontal hairline. They believe nutrition, sleep, and lifestyle impact hair health and are seeking ways to track hairline and medication use.

      community Age 20 vs Age 26 (Fin/Dut/Minoxidil)

       121 upvotes 1 year ago
      A user shared their hair loss journey, starting with Finasteride and Minoxidil in 2019, switching to Dutasteride in 2024, and adding topical Minoxidil and Tretinoin. They experienced slight temple thinning, which improved with Dutasteride, and reported no significant side effects except for thicker eyebrows and hair color change.