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      community A Technical Question About Pyrilutamide

      in Research/Science  5 upvotes 3 years ago
      Pyrilutamide is believed to be more effective than RU58841 and 1 mg finasteride in treating hair loss, with no systemic hormonal effects and the potential to block more than 31% of scalp DHT. It may also antagonize scalp testosterone due to its action as an androgen receptor antagonist.

      community 5 years on finastride + 2 years minoxidil success story (hairloss started at 18)

       14 upvotes 3 years ago
      A user shared their successful hair loss journey using finasteride for five years and minoxidil for two years, which stabilized and improved their hair condition. They experienced some shedding with minoxidil but found the routine manageable and are open to future treatments like dutasteride if needed.

      community DUT Risk profile for having kids?

       5 upvotes 3 years ago
      The user has been using a hair loss treatment including oral Minoxidil, topical Minoxidil with Tretinoin and Finasteride, and is considering adding Dutasteride but is concerned about the potential side effects and risks regarding fertility. A reply suggests that having children while on these medications should be fine, advising to avoid letting the partner come into contact with the drugs.

      community Topical finasteride with DMSO? Not sure what to do

       4 upvotes 4 years ago
      A user is considering using a 0.025% topical finasteride solution with DMSO to enhance absorption but is unsure about its effectiveness and safety. Other users express concerns about DMSO's properties and potential effects on the scalp.

      community Brain Fog - Finasteride ~2.5 months

      in Finasteride/Dutasteride  6 upvotes 4 years ago
      The user experienced decreased sex drive, weaker erections, and brain fog after taking 1mg Finasteride daily for about 2.5 months. They are considering stopping the treatment due to these side effects, and others in the conversation shared similar experiences with Finasteride and Minoxidil.

      community Finasteride ruined my hair, and my life (so far)

       9 upvotes 4 years ago
      The user suspects finasteride worsened their hair loss despite no abnormal shedding and reduced hair fall initially. They are considering various options, including switching brands, trying topical finasteride, oral minoxidil, or waiting for new treatments.

      community My GF says it’s working. Oral min, Dut, niz, micro needling, RU

       36 upvotes 4 years ago
      The user reports positive results in hair thickness using a regimen of oral minoxidil, dutasteride, microneedling, RU58841, and mk677. They experienced minimal side effects, noting only temporary discomfort after starting dutasteride.

      community 1MG Fin 14 Months Results

       161 upvotes 5 years ago
      A user's 14-month journey with finasteride, microneedling, and Nizoral to treat hair loss. They experienced some side effects such as ball ache, needing to pee constantly, and less semen, but the results were generally positive.

      community Anyone tried combining Finasteride and Ashwagandha?

       4 upvotes 5 years ago
      The conversation discusses using finasteride and ashwagandha for hair loss, with some users noting potential benefits and drawbacks. Minoxidil, peppermint oil, and creatine are also mentioned, with mixed opinions on their effectiveness.

      community Creatine and finasteride (DHT blocker)

       6 upvotes 5 years ago
      Creatine may increase DHT and potentially accelerate hair loss, but experiences vary. Finasteride, minoxidil, and microneedling are suggested to manage hair loss effectively.

      community Hopefully a logical question regarding dermarolling.

      in Microneedling 6 years ago
      A user discusses using dermastamping for hair loss and questions the timing of applying a mixture of peppermint oil, spearmint oil, rosemary oil, and castor oil due to their anti-inflammatory effects. They wonder if waiting 10 hours after stamping would be more effective.

      community For people that keep saying Breezula is weaker than fin...

       6 upvotes 6 years ago
      Breezula protects hair follicles from both testosterone and DHT, unlike finasteride, which only protects against DHT. This could potentially lead to significant hair regrowth, similar to results seen in transgender individuals using hormone blockers.

      community Exosomes - do they work as results look promising?

       2 upvotes 6 years ago
      Exosomes are being considered for hair regrowth, with some users reporting initial improvement. One user moved on to using dutasteride and oral minoxidil with positive results.

      community Finasteride sides succes story (AMA)

       19 upvotes 6 years ago
      A user shared their experience with finasteride, reporting severe side effects like erectile dysfunction and watery semen, which improved after stopping the medication. They emphasized the risks of finasteride and decided not to resume its use despite hair loss stabilization.

      community The new growth in hair loss research: With increasing evidence of its impact on mental health, scientists are pushing forward with breakthroughs on balding. Later this year, scientists will launch one of the first ever clinical trials with hair follicles grown entirely from stem cells.

       324 upvotes 7 years ago
      Hair loss impacts mental health, with treatments like Minoxidil, finasteride, and stem cell transplants discussed. There is hope for future breakthroughs, but current treatments are limited, and awareness is lacking.

      community Did anyone try dutasteride mesotherapy? scared of oral side effects (high DHT male here)

       4 upvotes 7 years ago
      A user is considering dutasteride mesotherapy for hair loss due to concerns about oral side effects from high DHT levels. They have been using topical finasteride with minoxidil but are exploring mesotherapy as an alternative, while another user shares their experience with mesotherapy sessions using dutasteride and minoxidil without side effects.

      community Starting Propecia with pre-existing erecticle dysfunction

       4 upvotes 9 years ago
      A 19-year-old with diffuse hair thinning and erectile dysfunction is considering starting Propecia (finasteride) while already using a minoxidil solution with anti-androgens. Concerns are raised about the psychological nature of erectile dysfunction and the potential systemic effects of anti-androgens, with suggestions to address porn addiction and consult a doctor about hormone therapy.

      community Is it worth using Minox without Fin?

       6 upvotes 10 years ago
      Minoxidil can regrow hair, but results vary and may decline over time. Finasteride is effective but carries a risk of side effects; using both together may yield the best results.

      community 8 Months of Treatment with Subpar Results

       22 upvotes 5 months ago
      The user has been using Dutasteride, Minoxidil, Ketoconazole, and RU58841 for hair loss but sees subpar results. Suggestions include adjusting treatments, considering a hair transplant, and addressing scalp inflammation.

      community Experiencing cognitive effects while on Dutasteride

       5 upvotes 1 week ago
      The user experienced fatigue, brain fog, and dizziness after taking Dutasteride for hair loss, suspecting it might be a side effect. They plan to consult a doctor and get blood work done, while others in the conversation discuss potential cognitive effects and compare Dutasteride to Finasteride.

      community Amplifica: Hope or Cope? A Review of Their Pipeline

       9 upvotes 1 month ago
      Amplifica's AMP-303 showed a modest increase in hair growth, but results were inconsistent and potentially misleading. Hyaluronic acid and osteopontin are being explored for hair growth, with varying effects on different hair types and conditions.

      community Prolactin the Cause of Hair Loss? ABS-201 the Cure?

       29 upvotes 2 months ago
      Prolactin may contribute to hair loss, but targeting its receptor won't cure androgenetic alopecia. ABS-201 could be a useful alternative or adjuvant therapy, similar to JAK inhibitors, but not more effective than HMI-115.

      community Finasteride 1MG and Minoxidil for 3.5 years. Scary diffuse shedding.

       185 upvotes 2 months ago
      The user has been experiencing significant hair shedding despite using finasteride and minoxidil for 3.5 years. They suspect the shedding could be due to stress, medication changes, or other factors, and are considering blood tests and additional treatments like oral minoxidil and serums.

      community 1.5 Year Hair Transformation on Finastride+Minoxidil (Need Honest Opinions)

       939 upvotes 3 months ago
      The user shared their 1.5-year progress using finasteride and minoxidil for hair regrowth, expressing satisfaction with the results but concern about plateauing and hairline issues. They are considering dutasteride and oral minoxidil but are worried about side effects, and they also struggle with using hair fibers for coverage.