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      community How can you make your own PP405

      in Research/Science  2 upvotes 1 year ago
      People are discussing making their own PP405 for hair loss treatment using JLX069 and DMSO. There is skepticism about the safety and effectiveness of this homemade solution, with some users expressing concerns about potential risks.

      community Hairline update - topical meds

       53 upvotes 1 year ago
      The conversation is about hair regrowth using topical finasteride, minoxidil, and keto spray, along with oral Saw Palmetto, Lustriva complex, collagen, and microneedling. Users discuss their experiences with these treatments, noting improvements in hair density and color, with some experiencing mild side effects.

      community You want growth but don't use a Dermaroller

       99 upvotes 10 months ago
      Using a dermaroller can enhance hair regrowth, especially when combined with minoxidil, and is recommended at depths of 0.75-1.5mm weekly. Microneedling boosts absorption and blood flow, and red light therapy is also being considered for hair growth.

      community I asked Gemini 2.5 Pro to roast r/tressless

      in Satire  35 upvotes 1 year ago
      Hair loss concerns and treatments like Minoxidil and Finasteride are humorously discussed. The community's quirks and dedication to battling hair loss are highlighted.

      community Bryan Johnson’s Hairloss Regimine

       27 upvotes 3 years ago
      The post is about Bryan Johnson's hair loss regimen, which includes dutasteride mesotherapy, minoxidil, microneedling, and red laser therapy. The conversation includes discussions about the effectiveness of topical dutasteride and speculation about whether Bryan Johnson has had a hair transplant.

      community Boston Transplant Update. Hairline & Crown procedures!

       5 upvotes 6 months ago
      The user underwent a hair transplant in Boston, initially dissatisfied with the results, but later achieved significant improvement in hair density and natural appearance after consulting a different surgeon. They used finasteride, minoxidil, and low-level laser therapy as part of their treatment.

      community Exosome PRP combined with Dutasteride and Oral Minoxidil?

       1 upvotes 5 months ago
      The user has been using Dutasteride and oral Minoxidil for hair loss but hasn't seen desired results and is considering Advanced PRP with autologous exosomes. Some users suggest these treatments are scams, while others discuss increasing Dutasteride dosage or exploring other options like low-level laser therapy.

      community This is all I’ll use to beat the Norwood reaper

      in Treatment  7 upvotes 1 year ago
      The conversation discusses a hair loss treatment regimen including 5% minoxidil, 2.5mg oral minoxidil, 1mg finasteride, tretinoin cream, derma stamping, derma rolling, scalp massagers, and a mix of vitamins and minerals. The user also considers using maca and adapalene, with advice on potential scalp irritation and the effectiveness of these treatments.

      community What new hair-loss treatments actually look exciting right now (Oct 2025)

       171 upvotes 11 months ago
      New hair loss treatments include Breezula, PP405, ET-02, KX-826, GT20029, VDPHL01, and CosmeRNA, with some showing promise in reactivating stem cells and reversing greying. Breezula and VDPHL01 are highlighted as potential add-ons or alternatives to current treatments like finasteride and minoxidil.

      community New molecule PP405 vs exercise

       36 upvotes 1 year ago
      PP405 targets hair follicle stem cells differently than exercise-induced lactate, suggesting exercise alone may not replicate its benefits. Minoxidil and finasteride are recommended alongside exercise for hair regrowth, with additional suggestions like spicy food and infrared exposure.

      community My 2-Year Journey – Meds Finally Kicking In

       345 upvotes 10 months ago
      The user experienced significant hair regrowth and reduced shedding after two years of using finasteride, minoxidil, and a laser helmet, along with maintaining scalp health with specific shampoos. Consistency and patience were key to their success, despite initial heavy shedding.

      community Dermastamping — do you use hyaluronic acid as lubricant?

       3 upvotes 1 year ago
      The conversation discusses using high molecular weight hyaluronic acid after microneedling to form a protective barrier, though it's considered expensive and offers marginal improvement. Users share experiences with different microneedling tools like derma rollers, dermastamps, and Dr. Pen, with some opting not to use any products on the scalp.

      community Are Derma Rollers Actually Harmful in the Long Run?

      in Microneedling  40 upvotes 1 year ago
      Derma rollers may cause scarring alopecia, leading some to prefer dermastamps or dermapens for microneedling. Combining minoxidil with microneedling is effective, but proper technique and healing time are essential to prevent damage.

      community Proposed Alternative stack to fin/min combination

      in Treatment 1 year ago
      A user proposed an alternative hair loss treatment stack using topical caffeine, copper, microneedling, and red light as a natural option for those experiencing side effects from finasteride or minoxidil. Other users expressed skepticism, emphasizing that finasteride and minoxidil remain the most effective treatments, while the proposed alternatives are unlikely to provide long-term results.

      community TDM-105795 phase 2 results are in!

       27 upvotes 2 years ago
      TDM-105795 showed promising hair growth results, with higher efficacy than placebo and minimal side effects. It activates dormant hair follicle stem cells and may maintain gains without immediate loss, unlike minoxidil.

      community The final nail in the coffin. PP405 is confirmed JXL069.

       440 upvotes 1 month ago
      PP405 and JXL069 are confirmed to be the same molecule, leading to disappointment due to poor hair regrowth results. Users express skepticism about the credibility of Pelage and the effectiveness of JXL069.

      community What are we thinking about combining Oral AND Topical Minoxidil?

       13 upvotes 6 months ago
      Combining oral and topical minoxidil for hair loss may enhance results, but opinions vary on its effectiveness. Some users report benefits, while others see no added value; side effects like insomnia and increased body hair are noted.

      community Am I A Good Candidate for a Procedure?

      1 year ago
      The user is using a topical solution with finasteride, minoxidil, and other ingredients, along with a red light laser cap and dermapen, to address hair thinning. They are considering a hair transplant but are advised to try dutasteride and oral minoxidil for 12 to 18 months before deciding.

      community Winlevi Clascoterone- resultssss

       4 upvotes 4 days ago
      The conversation is about using Winlevi Clascoterone cream for hair loss. The user is considering adding it to their routine, which includes a topical hair growth serum, and is seeking feedback on its effectiveness.

      community Who is the ideal target for PP405? Will it render hair trasplants obsolete?

       2 upvotes 5 months ago
      PP405 is being discussed as a potential treatment for hair loss, with uncertainty about its effectiveness compared to existing treatments like finasteride, dutasteride, and minoxidil. There is cautious optimism, but its impact on hair transplants remains unclear.

      community is this hyper responding? oral fin and min combi pill

       8 upvotes 1 year ago
      A 42-year-old experienced significant hair regrowth after 12 weeks on an oral combination of finasteride (1 mg) and minoxidil (2.5 mg), with noticeable improvements and no side effects. The user is considering continuing the treatment for a year due to the unexpected positive results.

      community KX-826 Max Version--Can This Formula Truly Combat Hairloss?

       3 upvotes 1 year ago
      KX-826 Max combines KX-826, Kopyrrol, and Kopexil as a potential alternative to minoxidil and finasteride for hair loss, but users express skepticism about its effectiveness and high cost. Some users believe traditional treatments like minoxidil, finasteride, and others are more reliable.