The trial for TDM-105795 has been completed, and it was in phase 2A. The discussion seeks input on the next phases, 2B or 3, based on safety and efficacy.
The conversation is about a user's progress with an oral treatment for hair loss using a stack of finasteride, minoxidil, and biotin over two months, noting stabilization after an initial shed. The user mentions using Hims Chews, which are effective but costly, and another user comments that biotin is ineffective.
A user had a second hair transplant with 2000 grafts, but saw no new growth after 8 months, unlike their first successful transplant. They are considering stem-cell treatment and plan to discuss the issue with the clinic that performed the procedure.
Hair regrowth using finasteride 1mg daily and topical minoxidil twice daily, with a hair transplant after three years, showed significant improvement over four years. The user is satisfied with the results despite not having access to oral minoxidil.
A user shared their 6-month progress using 1ml of Kirkland minoxidil daily and weekly 1mm dermarolling, noting no side effects and minimal shedding. They plan to consider finasteride or dutasteride after midterms, attributing hair loss to genetics.
The user maintained hair with finasteride for 4.5 years and noticed some progress with dutasteride after 6 months, experiencing reduced chest and facial hair. They did not use minoxidil and reported no side effects from either treatment.
The user reported gradual hair regrowth after 4 months using oral finasteride, topical minoxidil, dermastamping, and vitamins C and D3. They noted the use of a 1.25mm dermastamp and discussed sourcing finasteride in Canada.
A user shared their experience with hair loss treatment using dutasteride for 2 years and oral minoxidil for 1.5 years, noting some regrowth but not full recovery in temple areas. Suggestions included microneedling, topical minoxidil, and considering a hair transplant for further improvement.
A 21-year-old male experienced significant hair regrowth over a year using dutasteride, minoxidil, and ketoconazole shampoo. He noted improvements despite irregular application and mentioned that his hair is now thicker, with a previously bald spot completely gone.
The post discusses the completion of the HMI-115 Australian Phase 1 Trial for hair loss treatment. The user speculates about the potential early release of the trial results.
PP405 (Everychem 3HP) may help with hair regrowth, with mixed user experiences. Users often combine it with minoxidil and finasteride, but there are concerns about its efficacy and side effects.
A 24-year-old male experienced significant hair regrowth after 14 months of treatment with 0.5mg dutasteride and 5mg minoxidil, with no side effects reported. He plans to consider a hair transplant for his hairline, as the treatment did not improve that area.
Mixing minoxidil and stemoxydine is not recommended due to potential dilution and reduced effectiveness. Applying them separately with a time gap is suggested.
The user shared progress after six months using a topical mix of 0.3% finasteride and 6% minoxidil, reporting significant hair regrowth with minimal side effects. The product used is a spray from Hims, applied to the crown before bed.
Exosomes from mesenchymal stem cells can increase hair growth by enhancing anagen duration and hair shaft thickness through the Wnt/beta-catenin pathway. Phase 2 trials show improved hair counts over 24 weeks.
The conversation discusses a user's progress with hair regrowth after using Hims minoxidil and finasteride chews for 2.5 months, with some users expressing skepticism about the rapid results. The user also takes biotin, vitamin B5, vitamin B6, and vitamin C in a daily pill.
The user shared progress pictures showing improved hair density after 6 months of using finasteride and minoxidil. They advise consistency with the treatment and mention using finasteride and minoxidil tablets, sea salt spray, and matte clay paste in their hair routine.
The user shared progress pictures after 3 months of using oral dutasteride (0.5 mg) and minoxidil (2.5 mg), along with a derma roller and topical GHK-Cu serum. They noticed baby hairs growing and received advice to wait for further results, consider using a Dr. Pen instead of a derma roller, and check for scalp inflammation.
The user had a hair transplant in 2021 with 1600 grafts and is currently using finasteride, minoxidil, biotin, and collagen. They are considering another transplant in Turkey to address a bald spot and improve coverage in the front and middle.
The user is experiencing hair regrowth and thicker hair after two months using finasteride, biotin, a multivitamin with zinc, and Nizoral shampoo. The user expects significant improvement in hair regrowth after six months.
A 20-year-old male with diffuse androgenetic alopecia tried homeopathy for hair regrowth but saw limited results due to inconsistency and is considering switching to minoxidil and finasteride. Despite some baby hair growth, hair fall hasn't stopped, and he believes more time and consistency might be needed.
The user experienced significant hair growth using topical minoxidil 5%, finasteride 0.1%, and a 0.5 mm dermaroller weekly. They reported no side effects and are pleased with the results after 2.5 months.
Loniten 2.5mg is on backorder in Toronto, causing issues for those trying to start oral Minoxidil. Users suggest alternatives like splitting 10mg tablets or trying different brands.
A user experienced significant hair regrowth using dutasteride without side effects, starting with finasteride and not using minoxidil or dermarolling. They attributed success to a unique genetic response to DHT blockers but did not share their full regimen, frustrating others.
A transwoman shared her 11-month progress using hormone replacement therapy (HRT), finasteride, and minoxidil, reporting significant hair regrowth and satisfaction with the results. The discussion included various perspectives on HRT, its effects on hair and sexual function, and personal experiences with similar treatments.
The user started hair loss treatment at 19 with oral finasteride and topical minoxidil, later switching to oral Dutasteride and oral minoxidil. Despite ongoing treatments, including microneedling and topical applications, hair loss, particularly at the hairline, continues to progress.
A 48-year-old man has been using finasteride at 1mg three times a week for two years, seeing some hair regrowth but noting lighting affects appearance. He is considering adding minoxidil but is concerned about shedding.
The conversation is about using minoxidil and a dermaroller for hair loss treatment, with progress seen after 8 months. The user applies topical minoxidil twice daily and uses a dermaroller once a week, avoiding minoxidil 12 hours before and after rolling.
The user experienced significant hair regrowth over four months using 1 mg finasteride, 2.5 minoxidil, and occasional ketoconazole. They reported no side effects from the treatments.
A user shared their 4-month progress using minoxidil foam twice daily and 1 mg finasteride tablets, showing significant hair growth. The user reported no side effects from finasteride and used Propecia, the only available brand in their region.