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    Glossary17β-Hydroxysteroid Dehydrogenase

    enzyme that converts weaker sex hormones into more potent ones

    17β-Hydroxysteroid Dehydrogenase (17β-HSD) is an enzyme that plays a crucial role in the metabolism of steroids, including the conversion of weaker sex hormones into more potent ones. For example, it can convert androstenedione to testosterone and estrone to estradiol, which are important processes in regulating various physiological functions such as reproduction, hair growth, and overall hormonal balance.

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      community Quit vaping/smoking = 80% less loss

      in Research/Science  214 upvotes   4 months ago
      Quitting vaping significantly reduced hair loss for a user who was a heavy vaper and also taking finasteride. Some participants suggest nicotine's vasoconstrictive properties may worsen hair loss, while others share personal anecdotes of hair improvement after quitting smoking or vaping.

      community DHT and 5AR respect post, it's importance within the brain

      in Research/Science  109 upvotes   5 months ago
      The conversation discusses whether to use finasteride for hair loss, considering its role in inhibiting DHT and 5AR, which can affect brain function and mood. Some users report anxiety and depression from finasteride, while others do not experience these side effects and emphasize the importance of DHT for brain and prostate health.

      community What has helped you regrow your temples?

      in Chat  21 upvotes   1 year ago
      User seeks advice for regrowing temples, currently using Fin, oral Min, and dermarolling. Suggestions include improving scalp environment and considering RU58841 or dutasteride.

      community We need to keep these snake oil companies accountable.

      in Treatment  120 upvotes   2 months ago
      Biotin is being misleadingly marketed as a primary treatment for androgenic alopecia, overshadowing more effective treatments like finasteride and minoxidil. There is a call for increased awareness and accountability to prevent misinformation.

      community The truth about Dutasteride (w/ sources)

      in Finasteride/Dutasteride  51 upvotes   1 year ago
      The effectiveness of Dutasteride compared to Finasteride in treating hair loss, with evidence given such as studies and experiences, as well as discussion around whether one should switch from Finasteride to Dutasteride. There is also a discussion on post-Dutasteride syndrome.