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User TopBack56 and friends tried pyrilutamide (KX-826) for hair loss without experiencing negative side effects. They observed fine vellus hairs but no thick hair growth yet, and plan to add GT20029 to their regime after safety trials.

A 24 year old male struggling with the physical and mental effects of balding, being short, and having a micropenis. Suggested treatments include taking medications such as finasteride and minoxidil, lifting weights, and trying not to compare himself to others.

Evidence-based treatments for androgenic alopecia, such as minoxidil, finasteride, low-level laser light therapy, dutasteride, platelet-rich plasma, and topical ketoconazole. It discusses the efficacy, safety, and mechanism of action of these treatments, as well as future developments in understanding this polygenic condition.

Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.

Hair loss treatments discussed include Dutasteride with Ketoconazole, tissue engineering strategies, and androgenetic alopecia therapies. Massage doubles follicular retention, improving treatment effectiveness.

The user wants to reduce their dose of topical finasteride to 0.1-0.2mg and is considering mixing 0.2ml of their current finasteride + minoxidil serum with 0.8ml of a minoxidil-only serum for better scalp coverage. They are asking for advice on whether this method is effective or if there's a better way to dilute the finasteride solution.

The user has been using 5% minoxidil with 0.1% finasteride for 8 months with great results but noticed increased hair loss in winter. They also found vitamin deficiencies and improved their diet and exercise but are still experiencing hair loss.

A video suggests 0.6mm microneedling is more effective for hair regrowth than 1.2mm, as it causes less trauma to stem cells. People commonly believe 1.5mm is best, but this may vary based on individual factors.

The user shared a 15-month hair loss treatment update using Dutasteride (0.5mg/day), Minoxidil (5% foam twice daily), Nizoral (1% every 3 days), and a 1.5mm derma roller (twice a month), along with a multivitamin, exercise, low sugar diet, hydration, and consistent sleep. They started seeing results after 6-9 months, with significant improvement at the 1-year mark, and apply Minoxidil the day after derma rolling.

The conversation is about the proper frequency and needle length for microneedling to treat hair loss, with a user asking if they should use a 0.5 mm derma stamp daily and a 1.5 mm stamp once a week.

User takes topical finasteride/minoxidil with little results, asks if microneedling helps for temple regions and if 0.5mm is enough. Replies suggest microneedling is effective and 0.5mm works, sharing personal regimens.

The conversation discusses how the absorption rate of topical finasteride varies and is not equivalent to its oral form, with only a small percentage reaching the scalp. It also mentions that minoxidil in high concentrations is used topically because only a small amount is absorbed.

The conversation discusses using crushed finasteride tablets mixed with topical minoxidil for hair loss treatment. Users share their experiences and opinions on the effectiveness and proper concentration of this method.

Progesterone cream might help with hair loss by inhibiting DHT production and suppressing prolactin, which can increase DHT. Some dermatologists have used progesterone for hair loss treatment, and it has been effective, sometimes combined with minoxidil, finasteride, and hydrocortisone.

The conversation discusses the effectiveness of hair loss treatments, specifically finasteride and dutasteride. The conclusion is that dutasteride significantly reduces DHT levels and may be more effective than finasteride for long-term hair retention, with some users reporting personal experiences and side effects.

A user shared progress pictures after 4 months of using topical finasteride and minoxidil, dutasteride, rosemary oil shampoo, ketoconazole, and pumpkin seed oil, reporting great results and increased hair thickness. Other users commented on the mild initial hair loss and congratulated the user on their success.

The regimen for hair loss includes topical finasteride, clascoterone, tretinoin, minoxidil, oral saw palmetto, beta-sitosterol, vitamin D, microneedling, and anti-fungal shampoo. Expected benefits are increased hair growth and density, with considerations for potential skin irritation and interactions between treatments.

User shared 9-month hair regrowth progress using a Fin/Min spray from HIMS, with additional microneedling. Other users praised the results and discussed the effectiveness of topical treatments.

The conversation discusses the impact of finasteride on sexual function, with many users reporting reduced libido and weaker erections despite continuing the treatment to prevent hair loss. Some users suggest checking hormone levels or switching to different dosages or treatments like dutasteride, while others share mixed experiences regarding the severity of side effects.

The conversation discusses skepticism around claims that dutasteride worsens hair loss, with some users suggesting misinformation or panic during shedding as reasons for such claims. One user shared their negative experience with dutasteride, including increased sebum production and hair loss, and is now considering a higher dose of oral minoxidil after stopping dutasteride.

The post discusses the potential of upregulating aromatase to treat hair loss, suggesting that increasing CCL2 levels through Vitamin D or microneedling might help. The user questions why microneedling doesn't work for everyone, especially those with advanced hair loss.

Finasteride can aid hair regrowth but may cause side effects like depression and sexual dysfunction. Users discuss experiences with finasteride, minoxidil, and RU58841, highlighting varied responses and the importance of informed treatment choices.

The conversation discusses using very low dose topical finasteride to achieve specific serum DHT reduction percentages. It concludes that finasteride dosage increases linearly between 5-30% DHT reduction but requires exponential increases for reductions up to 70%.

The user is exploring hair growth stimulants other than Minoxidil, mentioning Stemoxydine, various peptides, drugs like Latanoprost and Bimatoprost, and natural remedies such as Rosemary Oil and Caffeine. They express concerns about the long-term effectiveness and safety of these alternatives and seek more information on viable options for hair regrowth.

The user has been using Hims finasteride and minoxidil spray, nizoral shampoo twice a week, and a daily biotin gummy for 90 days to treat hair loss. The user and others discuss the cost, dosage, and effectiveness of the treatment, with some suggesting cutting hair short for better results.

The conversation is about an 18-year-old's progress with hair regrowth using oral Minoxidil, dermarolling, and RU58841 over three months, starting treatment after beginning to lose hair at 16. Participants are impressed with the improvement and encourage continued treatment.

The potential health risks associated with long-term use of finasteride and dutasteride, with some responses pointing out the low quality of the journal that published the review article as well as highlighting other alternatives such as keto or minoxidil, and RU58841.

A user experienced significant hair shedding and thinning 10 months post-hair transplant despite using minoxidil and topical finasteride. They are considering switching to oral finasteride or dutasteride and are also dealing with scalp conditions like seborrheic dermatitis.

A user shared their successful 50-day progress using oral minoxidil and finasteride for hair loss. They plan to switch to dutasteride after six months for potentially better results.

The original poster believes shaving his head made him more attractive to a specific group of women, despite being less attractive overall. The conversation includes various opinions on attractiveness, with some agreeing that being bald can work for certain men, while others suggest maintaining hair is generally more appealing.