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5 / 16 resultslearn Alopecia Areata
autoimmune disorder causing patchy hair loss
learn Exosomes
Microscopic delivery system that sends growth-promoting signals to hair follicles
learn Platelet-Rich Plasma
growth factors taken from your blood and injected into your scalp to stimulate hair
learn Follistatin
glycoprotein that inhibits TGF-β and promotes hair growth by antagonizing activin
Research
5 / 1000+ results![Epigenetic control of adult stem cell function](/images/research/919d1eab-dda9-47cb-a637-ce0b7f38192e/small/19607.jpg)
research Epigenetic control of adult stem cell function
Epigenetic changes control how adult stem cells work and can lead to diseases like cancer if they go wrong.
![Endogenous retinoids in the hair follicle and sebaceous gland](/images/research/7ecfec1f-bd39-4f18-ac0c-91b19b89b51d/small/24584.jpg)
research Endogenous retinoids in the hair follicle and sebaceous gland
Maintaining the right amount of retinoic acid is crucial for healthy hair and skin.
![Intracrine androgen biosynthesis, metabolism and action revisited](/images/research/f125b0de-3ea8-49d8-9709-b4c930631e8d/small/20931.jpg)
research Intracrine androgen biosynthesis, metabolism and action revisited
The document concludes that blocking the internal pathways that create androgens might help treat cancers that depend on sex hormones.
![Cholesterol homeostasis: Links to hair follicle biology and hair disorders](/images/research/9ec8bdc1-5995-4b01-83ab-1ef36ea6dc07/small/13394.jpg)
research Cholesterol homeostasis: Links to hair follicle biology and hair disorders
Cholesterol balance is important for hair health, and problems with it can lead to hair loss conditions.
![Structural & functional studies of L-PGDS and SMPDL3A enzymes in lipid signaling family](/images/research/23c8c71d-c7b6-4a57-93f8-5d373e42fce8/small/37007.jpg)
research Structural & functional studies of L-PGDS and SMPDL3A enzymes in lipid signaling family
L-PGDS has specific binding sites for its functions and could help in drug delivery system design.
Community Join
5 / 250 resultscommunity FCE 28260: A Forgotten 5α-Reductase Inhibition
FCE 28260 (PNU 156765), an under-explored 5α-reductase inhibitor, showcases promising results in research by Giudici et al., outperforming well-known treatments like Finasteride in reducing the conversion of testosterone to DHT. Its superior efficacy, demonstrated through lower IC50 values in both natural and human recombinant enzyme studies, suggests it could offer more effective management of DHT-related conditions. Additionally, its lower molecular weight hints at better potential for topical application, potentially offering advantages in treating conditions such as androgenic alopecia. Despite its potential, it has not advanced in development, possibly due to financial limitations, leaving its therapeutic prospects and side effect profile largely unexplored.
community I will have it cured by morning
Researching the cause of hair loss and treating it by preventing DHT in the scalp with medication such as finasteride or dutasteride, estrogen, minoxidil, dermarolling, and possible topical antiandrogens.
community Anything you use without scientific backing, just trusting your gut?
The conversation discusses using peppermint oil for hair loss, with one user applying it undiluted to the scalp and another combining it with finasteride and microneedling. Some believe in its effectiveness despite limited scientific evidence, and also mention rosemary oil as potentially beneficial.
community Looks like a real cure to the root of baldness (DHT-induced senescence) was proven earlier this year
A study that outlines the full model for androgenic alopecia (AGA) which links DHT to cellular senescence in dermal papilla cells, and suggests black chokeberry as a source of cyanidin 3-O-arabinoside polyphenol with potential anti-oxidant properties that could reverse this process. The post encourages reaching out to experts in anti-aging and longevity to research treatments involving the polyphenol.
community My Theory Regarding a Cause and Cure for Androgenetic Alopecia
Hair loss theory suggests imbalance between Vitamin D Receptor (VDR) and Androgen Receptor (AR) activation. Proposed treatment includes upregulating VDR, downregulating AR, and improving mitochondrial health.