research CXCR3 Blockade Inhibits T Cell Migration Into the Skin and Prevents Development of Alopecia Areata
Blocking the CXCR3 receptor reduces T cell accumulation in the skin and prevents hair loss in mice.
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5 / 1000+ results research Induction of T Cell Exhaustion by JAK1/3 Inhibition in the Treatment of Alopecia Areata
Ifidancitinib, a JAK inhibitor, effectively regrows hair in mice with alopecia by tiring out harmful T cells.
research Dormant Tumor Cells in Ret Transgenic Mouse Melanoma Model and Their Interaction with Memory T Cells
Dormant melanoma cells in mice interact minimally with memory T cells due to a suppressive tumor environment.
research Selective Inhibition of JAK3 Signaling Is Sufficient to Reverse Alopecia Areata
Blocking JAK3 signaling can reverse hair loss from alopecia areata.
research Stress-Induced Sympathetic Hyperactivation Drives Hair Follicle Necrosis to Trigger Autoimmunity
Stress can cause hair loss and trigger autoimmunity by damaging hair follicle cells.
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