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This study found that Carthamus tinctorius extract significantly increased the length of cultured hair follicles and may be a promising topical agent for hair growth promotion with high skin permeation.

This study found that Carthamus tinctorius floret ethanolic extract stimulated melanogenesis in B16F10 murine melanoma cells without cytotoxicity, suggesting its potential as a treatment for gray hair.

The study observed that Carthamus tinctorius extract-loaded lipid carriers promoted hair growth in C57BL/6 mice more effectively than minoxidil, although further research on humans is needed for confirmation.

This study found that hydroxysafflor yellow A-rich Carthamus tinctorius extract promoted hair growth and gene expression linked to hair proliferation in both cell cultures and mouse models.

This study found that Carthamus tinctorius floret extract, at a concentration of 0.05 mg/mL, significantly inhibited 5α-reductase activity in DU-145 cells more effectively than standard treatments finasteride and dutasteride, with a stable microemulsion formulation enhancing its skin permeation and stability.