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GlossaryBurkitt's lymphoma

highly aggressive cancer of B cells often linked to Epstein-Barr virus

Burkitt's lymphoma is a highly aggressive type of non-Hodgkin lymphoma that originates from B cells, a type of white blood cell. It is most commonly associated with a translocation involving the MYC gene on chromosome 8, leading to uncontrolled cell growth. This cancer is often linked to the Epstein-Barr virus and is prevalent in children in certain regions of Africa, but it can also occur in other parts of the world. Prompt diagnosis and intensive chemotherapy are crucial for effective treatment.

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research The JAK/STAT Signaling Pathway: From Bench to Clinic

489 citations, November 2021 in “Signal Transduction and Targeted Therapy”

The JAK/STAT pathway is important in cell processes and disease, and JAK inhibitors are promising for treating related conditions.

Integrative Analysis of Rare Copy Number Variants and Gene Expression Data in Alopecia Areata Implicates an Etiological Role for Autophagy

research Integrative Analysis of Rare Copy Number Variants and Gene Expression Data in Alopecia Areata Implicates an Etiological Role for Autophagy

20 citations, June 2019 in “Experimental Dermatology”

The research suggests that autophagy-related genes might play a role in causing alopecia areata.

research Oral Signs of Hematologic Disease

2 citations, January 2019 in “Springer eBooks”

The conclusion is that different blood diseases cause specific oral symptoms and require varied treatments to manage these symptoms and improve patient health.

research Telogen Effluvium Following Orthognathic Surgery

1 citations, June 2007 in “Journal of Oral and Maxillofacial Surgery”

A woman experienced temporary hair loss after jaw surgery due to the stress of the operation.

research Evidence That Myc Activation Depletes the Epidermal Stem Cell Compartment by Modulating Adhesive Interactions with the Local Microenvironment

182 citations, May 2003 in “Development”

Myc activation reduces skin stem cells by affecting cell adhesion.

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