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An Innovative Phase 1b Trial Demonstrating Proof-of-Pharmacology for Two Novel IRAK4-Inhibitors Using a Local and Systemic Driven Immune Response

research An Innovative Phase 1b Trial Demonstrating Proof-of-Pharmacology for Two Novel IRAK4-Inhibitors Using a Local and Systemic Driven Immune Response

April 2023 in “Journal of Investigative Dermatology”

Two new IRAK4-inhibitors effectively reduced skin inflammation and immune response markers in healthy volunteers.

research Kinase Inhibition with BAY 43-9006 in Renal Cell Carcinoma

234 citations, September 2004 in “Clinical cancer research”

BAY 43-9006 helps control kidney cancer growth but doesn't significantly increase overall survival.

research Adult-Onset Hair Loss in Chesapeake Bay Retrievers: A Clinical and Histological Study

8 citations, February 2005 in “Veterinary dermatology”

Chesapeake Bay retrievers' hair loss is likely a breed-specific, hereditary condition linked to abnormal steroid levels and distinct skin changes.

Effects of Nitrendipine, Nifedipine, Verapamil, Phentolamine, Papaverine, and Minoxidil on Contractions of Isolated Rabbit Aortic Smooth Muscle

research Effects of Nitrendipine, Nifedipine, Verapamil, Phentolamine, Papaverine, and Minoxidil on Contractions of Isolated Rabbit Aortic Smooth Muscle

47 citations, November 1982 in “Journal of Cardiovascular Pharmacology”

Nitrendipine and nifedipine effectively block muscle contractions, while papaverine relaxes them and minoxidil needs high amounts to work.

Monoclonal Antibody Against Prolactin Receptor: A Randomized Placebo-Controlled Study Evaluating Safety, Tolerability, and Pharmacokinetics of Repeated Subcutaneous Administrations in Postmenopausal Women

research Monoclonal Antibody Against Prolactin Receptor: A Randomized Placebo-Controlled Study Evaluating Safety, Tolerability, and Pharmacokinetics of Repeated Subcutaneous Administrations in Postmenopausal Women

3 citations, May 2018 in “Reproductive Sciences”

The drug BAY 1158061 is safe, well-tolerated, and shows potential for treating diseases related to prolactin.

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Community Join

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community Journey and recommendation for Bay Area doctor

in Treatment 2 upvotes 9 months ago

The user has tried various hair loss treatments including minoxidil, finasteride, and others, experiencing side effects and is seeking recommendations for a knowledgeable doctor in the California Bay Area. They had a negative experience with one doctor and are considering a hair transplant but want to avoid further side effects.

community Any Recommendations For Exosome Treatments In The Greater Sacramento Area?

in Treatment 2 upvotes 3 months ago

A user is seeking recommendations for dermatologists or hair clinics in the Greater Sacramento or Bay Area for exosome treatments, comparing topical application plus microneedling versus direct scalp injections. They are also asking for personal experiences and before-and-after photos.

community Somebody has gotta try this- HMI-115 reference anti-body

in Treatment 14 upvotes 1 year ago

The potential of using a specific antibody, HMI-115, as a treatment for hair loss alongside traditional treatments such as minoxidil and finasteride. The user suggests trying either a 240 mg or 30 mg dose to see if it works.

community Min and retinol? Anyone tried it?

in Research/Science 5 upvotes 11 months ago

The conversation discusses using minoxidil with retinol for hair loss treatment. Users share their experiences and opinions on the effectiveness of this combination.

community Scalp is constantly uncomfortable and irritated with lots of hair loss

in Chat 7 upvotes 6 months ago

The individual has experienced a sore, stiff, and itchy scalp with hair loss for 4.5 years, and has noticed increased thinning and miniaturized hairs, especially at the temples. They have tried ketoconazole shampoo without success and are considering finasteride for treatment.

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