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This study provides evidence that human skin contains genes and enzymes necessary for producing serotonin and melatonin.

This study found that mouse skin can produce and metabolize serotonin and N-acetylserotonin, with activity influenced by location, physiological skin status, cell type, and mouse strain.

This chapter reviews existing knowledge about melatonin's MT₁ and MT₂ receptors in human tissues, discussing their established and potential functions, but reports no new clinical findings.

This study found that murine skin is a target for melatonin bioregulation, as melatonin affected DNA synthesis and tyrosinase activity in skin organ culture.

This article discusses the potential role of melatonin in protecting skin against stress and maintaining homeostasis, based on its local synthesis and various protective functions, but presents no new clinical results.