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GlossaryAmitriptyline (Amitriptyline Hydrochloride)

tricyclic antidepressant used for depression and chronic pain

Amitriptyline, also known by the brand name Elavil, is a tricyclic antidepressant commonly used to treat mental/mood disorders such as depression. It works by affecting the balance of certain natural chemicals (neurotransmitters like serotonin) in the brain, and it can also be prescribed for chronic pain management, migraines, and certain types of nerve pain.

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research Scalp Dysesthesia: A Study on Chronic Pain and Itchiness

63 citations , March 1998 in “Archives of Dermatology”

Antidepressants may improve or resolve scalp dysesthesia in most patients.

research Towards Sustainable and Scalable Synthesis of Amitriptyline Hydrochloride, Minoxidil, and Pyrrolidinyl Diaminopyrimidine Oxide

1 citations , May 2025 in “Journal of the Indian Chemical Society”

Controversies in Off-Label Prescriptions in Dermatology: The Perspective of the Patient, the Physician, and the Pharmaceutical Companies

research Controversies in Off-Label Prescriptions in Dermatology: The Perspective of the Patient, the Physician, and the Pharmaceutical Companies

8 citations , August 2018 in “International Journal of Dermatology”

The document concludes that doctors should carefully consider off-label drug use in dermatology and always inform patients, while more research is needed on the safety and effectiveness of such practices.

research Psychodermatology: Emotional Factors and Treatment Approaches

41 citations , March 1992 in “Archives of Dermatology”

The review suggests that understanding and treating the psychological aspect of skin disorders is important and calls for more collaboration in this field.

research Scalp Dysesthesia Related to Cervical Spine Disease

33 citations , November 2012 in “JAMA Dermatology”

Most women with weird scalp feelings had neck spine problems, and some got better with gabapentin treatment.

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