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GlossaryAmitriptyline (Amitriptyline Hydrochloride)

tricyclic antidepressant used for depression and chronic pain

Amitriptyline, also known by the brand name Elavil, is a tricyclic antidepressant commonly used to treat mental/mood disorders such as depression. It works by affecting the balance of certain natural chemicals (neurotransmitters like serotonin) in the brain, and it can also be prescribed for chronic pain management, migraines, and certain types of nerve pain.

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research Scalp Dysesthesia: A Study on Chronic Pain and Itchiness

63 citations, March 1998 in “Archives of Dermatology”

Antidepressants may improve or resolve scalp dysesthesia in most patients.

research Adverse Cutaneous Reactions to Antidepressants

44 citations, January 2002 in “American Journal of Clinical Dermatology”

Skin reactions to antidepressants are common but usually not serious and can be treated.

research Psychodermatology: Emotional Factors and Treatment Approaches

41 citations, March 1992 in “Archives of Dermatology”

The review suggests that understanding and treating the psychological aspect of skin disorders is important and calls for more collaboration in this field.

research Scalp Dysesthesia Related to Cervical Spine Disease

33 citations, November 2012 in “JAMA Dermatology”

Most women with weird scalp feelings had neck spine problems, and some got better with gabapentin treatment.

research Review of Cardiovascular Findings in Humans Treated with Minoxidil

28 citations, January 1989 in “Toxicologic Pathology”

Minoxidil may cause heart changes; use caution and monitor patients with heart conditions.

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