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    Did you mean Frontal Fibrosis Alopecia?
    GlossaryFrontal Fibrosing Alopecia

    scarring hair loss at the front hairline, often in postmenopausal women

    Frontal Fibrosing Alopecia (FFA) is a type of scarring hair loss that primarily affects postmenopausal women, though it can occur in men and younger women. It is characterized by a progressive recession of the frontal hairline and often includes loss of eyebrows and other body hair. The condition is thought to be an autoimmune disorder, where the body's immune system mistakenly attacks hair follicles, leading to inflammation and permanent hair loss.

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      research Frontal Fibrosing Alopecia: A Literature Review

      March 2025 in “Revista Foco”
      Alopecia Frontal Fibrosante (AFF) is a primary scarring alopecia characterized by irreversible hair loss in the frontotemporal region, with increasing global incidence posing a challenge for dermatologists. Early diagnosis is crucial for effective treatment, as it allows intervention during potentially reversible stages. The etiology is not fully understood but may involve autoimmune, hormonal, and genetic factors, with chronic inflammation and perifollicular fibrosis leading to irreversible hair loss. Clinically, AFF presents with frontotemporal alopecia, possible eyebrow involvement, facial papules, hyperpigmentation, and symptoms like itching and pain. Diagnosis is confirmed via scalp biopsy, with trichoscopy aiding in monitoring. Treatment varies, including topical and intralesional corticosteroids, calcineurin inhibitors, 5-alpha reductase inhibitors, hydroxychloroquine, and isotretinoin, with hair transplantation as an option for severe cases. This literature review analyzed 16 articles from 2018 to 2024, aiming to describe clinical signs, symptoms, and trichoscopic findings to guide diagnosis and improve patient prognosis.

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