December 2024 in “Brazilian Journal of Health Review” Early diagnosis of alopecia frontal fibrosante is crucial, but treatment remains controversial and varies.
2 citations
,
December 2018 Alopecia frontal fibrosante affects facial vellus hair and can be diagnosed with dermatoscopy.
March 2025 in “Revista Foco” Alopecia Frontal Fibrosante (AFF) is a primary scarring alopecia characterized by irreversible hair loss in the frontotemporal region, with increasing global incidence posing a challenge for dermatologists. Early diagnosis is crucial for effective treatment, as it allows intervention during potentially reversible stages. The etiology is not fully understood but may involve autoimmune, hormonal, and genetic factors, with chronic inflammation and perifollicular fibrosis leading to irreversible hair loss. Clinically, AFF presents with frontotemporal alopecia, possible eyebrow involvement, facial papules, hyperpigmentation, and symptoms like itching and pain. Diagnosis is confirmed via scalp biopsy, with trichoscopy aiding in monitoring. Treatment varies, including topical and intralesional corticosteroids, calcineurin inhibitors, 5-alpha reductase inhibitors, hydroxychloroquine, and isotretinoin, with hair transplantation as an option for severe cases. This literature review analyzed 16 articles from 2018 to 2024, aiming to describe clinical signs, symptoms, and trichoscopic findings to guide diagnosis and improve patient prognosis.
26 citations
,
August 2016 in “Actas Dermo-Sifiliográficas” Frontal Fibrosing Alopecia in men is often missed and can come with symptoms like facial bumps and hair loss on eyebrows and limbs.
54 citations
,
November 2007 in “Actas Dermo-Sifiliográficas” Early diagnosis of frontal fibrosing alopecia is crucial to prevent permanent hair loss.