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5 / 1000+ results![11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17α-hydroxylase/17,20-lyase to produce C11α-derivatives of 21-deoxycortisol and 11-hydroxyandrostenedione in vitro](/images/research/b7800701-25f8-4cd8-bfab-bd071e9be6a6/small/13469.jpg)
research 11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17α-hydroxylase/17,20-lyase to produce C11α-derivatives of 21-deoxycortisol and 11-hydroxyandrostenedione in vitro
11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.
![Nonclassic congenital adrenal hyperplasia and the heterozygote carrier](/images/research/f45b153c-c622-4097-b4e6-d777c8799021/small/20288.jpg)
research Nonclassic congenital adrenal hyperplasia and the heterozygote carrier
Identifying nonclassic congenital adrenal hyperplasia and carriers of CYP21 mutations is challenging, and genetic counseling is recommended due to their prevalence.
![Adrenal 21-hydroxylase gene mutations in Slovenian hyperandrogenic women: evaluation of corticotrophin stimulation and HLA polymorphisms in screening for carrier status](/images/research/fbc2bbc7-84be-452e-b46f-ba7306ebbd41/small/15551.jpg)
research Adrenal 21-hydroxylase gene mutations in Slovenian hyperandrogenic women: evaluation of corticotrophin stimulation and HLA polymorphisms in screening for carrier status
The study concluded that testing hormone levels after stimulation is not reliable for identifying carriers of 21-hydroxylase deficiency; genetic testing is necessary.
![Carriers of 21-Hydroxylase Deficiency Are Not at Increased Risk for Hyperandrogenism*](/images/research/3fee48c6-c5ee-4670-a079-81bca7df0575/small/15599.jpg)
research Carriers of 21-Hydroxylase Deficiency Are Not at Increased Risk for Hyperandrogenism*
People who carry the 21-Hydroxylase Deficiency gene are not more likely to have excessive male hormone levels.
![LC-MS/MS improves screening towards 21-hydroxylase deficiency](/images/research/dc6801fa-9911-4b23-ad33-c1d630e9927c/small/14402.jpg)
research LC-MS/MS improves screening towards 21-hydroxylase deficiency
LC-MS/MS is more reliable than immunoassays for diagnosing 21-hydroxylase deficiency.
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5 / 703 resultscommunity Only 10 more days until cassiopea releases their 12 month results for CB-03-01 our best hope of an alternative to finasteride
The conversation discusses anticipation for CB-03-01, a potential new hair loss treatment that may be more effective and have a cleaner safety profile than finasteride. Users are hopeful but cautious, discussing current treatments like minoxidil, nizoral, and dermarolling, and the possibility of combining them with CB-03-01 for better results.
community PSA: Most men who stay on Fin will see the sexual side effects go away. Stop the fear mongering
Finasteride can cause sexual side effects in less than 2% of men, but these often disappear over time, even if the treatment continues. Some users report persistent side effects, while others experience no issues or only temporary ones.
community 21 months on topical minoxidil and full HRT
The conversation is about a transgender individual's experience with hair regrowth using topical minoxidil and hormone replacement therapy (HRT), expressing concern about the slow growth and thin appearance of their hair. Some responses encourage patience and highlight the variability of results, while others discuss the role of HRT and its effects.
community 21 Month Finasteride+13 Month Minoxidil+2 Month Stemoxydine
The post discusses a 21-month treatment of hair loss using Finasteride, a 13-month treatment with Minoxidil, and a 2-month treatment with Stemoxydine. Replies suggest enhancing results by adding a micro needling pen and tretinoin to the regimen, and consider Finasteride and Minoxidil as crucial treatments.
community 21 yo m on Finasteride/minoxidil/ketoconazole shampoo 4.5 month update: starting to notice some solid results! Temples are starting to fill in and my overall density is improving. Comments/suggestions on my protocol? I’d love to hear what you guys think.
This conversation is about a 21-year old male's success with using finasteride, minoxidil and ketoconazole shampoo to regrow his hair. He increased the finasteride dosage from 1mg 3x per week to 1 mg daily for maximum results. People in the thread commended him on his progress.