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research Synthesis and Study of Some 17a-Aza-D-Homo Steroids as 5α-Reductase Inhibitors

1 citations, October 2020 in “Current Drug Discovery Technologies”

The research found that compound 6, a newly created steroid, is more effective at inhibiting 5α-reductase (an enzyme) than current treatments, suggesting it could be a better option for treating urinary tract symptoms in men.

research Synthesis and Biological Evaluation of Novel Unsaturated Carboxysteroids as Human 5α-Reductase Inhibitors: A Legitimate Approach

17 citations, June 2012 in “European journal of medicinal chemistry”

New steroid compounds effectively inhibit 5α-reductase and may treat hair loss.

research Steroidal 5α-Reductase and 17α-Hydroxylase/17,20-Lyase (CYP17) Inhibitors Useful in the Treatment of Prostatic Diseases

51 citations, May 2013 in “The Journal of Steroid Biochemistry and Molecular Biology”

Certain drugs that block specific enzymes can help treat prostate diseases.

research Recent Advances in Oxasteroids Chemistry

41 citations, March 2007 in “Steroids”

New methods to make oxasteroids show promise for medical treatments like osteoporosis and breast cancer.

research Androgen Antagonists in Androgen Target Tissues

27 citations, January 1984 in “Pharmacology & Therapeutics”

Antiandrogens have important biological effects, but more research is needed to understand them fully and compare their effectiveness and side effects to other treatments.

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Community Join

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community Clinical Trial: Clascoterone (Cortexolone 17A-Propionate)

in Research/Science 24 upvotes 9 months ago

A user is joining a clinical trial for Clascoterone, a drug approved for acne but being tested for hair loss. They previously tried finasteride with limited success and plan to share updates on their experience with the new treatment.

community Anyone here who’s using Alfatradiol (17a-Estradiol) in consistency with some results?

in Treatment 7 upvotes 3 years ago

User discusses Alfatradiol (17a-Estradiol) as a potential hair loss treatment with mixed results. Concerns include low dosage, receptor theory, and possible increased aromatase activity on scalp.

community I live in the US. Where are most reputable places to purchase either Alfatradiol or Pyralutamide?

in Product 3 upvotes 2 months ago

The user is considering adding Alfatradiol or Pyralutamide to their current hair loss treatment of oral Dutasteride and Minoxidil. They are seeking advice on experiences and purchasing options for these products in the US.

community Alfatradiol is a topical 5AR inhibitor that this study shows is effective in stopping hair loss without sides. It can be bought OTC in Europe right now. Thoughts?

11 upvotes 8 years ago

Hair loss treatments, specifically the use of Alfatradiol as an over-the-counter topical 5AR inhibitor that has been shown to be effective in stopping hair loss without side effects. Other treatments discussed include Minoxidil, finasteride and RU58841.

community 10 months CB and Oral Minoxidil

in Progress Pictures 111 upvotes 9 months ago

A person with Alopecia Areata on their beard is using CB-03-01 and oral minoxidil for treatment. Some users question the effectiveness of CB-03-01 for beard hair, suggesting that minoxidil alone may be responsible for any observed hair growth.

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