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Research

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research Accelerative action of topical piperonylic acid on mice full thickness wound by modulating inflammation and collagen deposition

3 citations , October 2021 in “PLoS ONE”

In this study, topical piperonylic acid was found to improve wound healing in mice by activating EGFR and modulating gene expression related to the healing process.

Stimulation of the Follicular Bulge LGR5+ and LGR6+ Stem Cells with the Gut-Derived Human Alpha Defensin 5 Results in Decreased Bacterial Presence, Enhanced Wound Healing, and Hair Growth from Tissues Devoid of Adnexal Structures

research Stimulation of the Follicular Bulge LGR5+ and LGR6+ Stem Cells with the Gut-Derived Human Alpha Defensin 5 Results in Decreased Bacterial Presence, Enhanced Wound Healing, and Hair Growth from Tissues Devoid of Adnexal Structures

39 citations , October 2013 in “Plastic and Reconstructive Surgery”

In this study, researchers found that intestine-derived human alpha defensin 5 enhances wound healing, reduces bacterial load, and promotes hair growth in murine burn wound beds by increasing LGR stem cell migration.

High-Performance Liquid Chromatographic Determination of Finasteride in Human Plasma Using Direct Injection with Column Switching

research High-performance liquid chromatographic determination of finasteride in human plasma using direct injection with column switching

29 citations , February 1996 in “Journal of Chromatography B: Biomedical Sciences and Applications”

This study developed a fully automated HPLC method for accurately quantifying finasteride in human plasma, achieving a detection limit of 1 ng/ml with validated application in pharmacokinetic studies.

A Randomized, Double-Blind, Placebo and Active Controlled Phase II Study to Evaluate the Safety and Efficacy of Novel Dutasteride Topical Solution (0.01%, 0.02%, and 0.05% w/v) in Male Subjects With Androgenetic Alopecia

research A Randomized, Double-Blind, Placebo and Active Controlled Phase II Study to Evaluate the Safety and Efficacy of Novel Dutasteride Topical Solution (0.01%, 0.02%, and 0.05% w/v) in Male Subjects With Androgenetic Alopecia

August 2025 in “Cureus”

This phase II study found that a 0.05% topical dutasteride solution was more effective than oral finasteride (1 mg/day) in increasing hair count and width in males with androgenetic alopecia over 24 weeks, without causing irritation.

research Local Pharmacokinetics and Tolerability of Topically‐Applied Bimatoprost to the Scalp of Male Patients With Androgenetic Alopecia

August 2026 in “Clinical and Translational Science”

This study evaluated two bimatoprost 1% formulations for androgenetic alopecia in men, finding both formulations achieved effective drug concentrations in the scalp with no significant differences between them, and were well tolerated over the 14-day application period.

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Community Join

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community 6 months of min 2x a day + .25mg fin 1x a day

in Progress Pictures 252 upvotes 2 years ago

A user shared progress pictures after 6 months of using minoxidil twice daily and 0.25mg finasteride once daily for hair loss. The conversation includes comments on the user's posture in the photos and slight improvements in hair fullness.

community (M23)Been on DUT for a year and 1 month- so is a transplant not a good option if DUT doesn’t work🤷‍♂️

in Progress Pictures 25 upvotes 1 year ago

The user has been using Dutasteride for over a year for hair loss and is considering a hair transplant if it doesn't work. Suggestions include adding Minoxidil and microneedling, but some advise against a transplant as the current treatment seems effective.

community I’m considering stopping finasteride

in Finasteride/Dutasteride 157 upvotes 8 months ago

The user is considering stopping finasteride due to depression, anxiety, and difficulty building muscle, despite its effectiveness in stopping hair loss. Suggestions include reducing the dose, switching to topical solutions, or consulting a doctor for alternatives like dutasteride or RU58841.

community Dutasteride (.5mg) is some strong stuff!

54 upvotes 4 years ago

User switched from finasteride and minoxidil to dutasteride, experienced side effects, then took dutasteride once a week with improved hair density. Another user had success with daily dutasteride, while one had no results from topical dutasteride.

community Hairloss Treatment - General health and efficacy-conscious stack overview

1 year ago

The conversation discusses managing hair loss and seborrheic dermatitis with treatments like minoxidil, finasteride, and saw palmetto, emphasizing the importance of scalp health and DHT reduction. The user shares personal experiences and suggests a balanced approach, combining topical treatments and lifestyle changes for effective hair regrowth.

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Learn

2 / 801 results

learn Hair Transplant

What happens after a hair transplant? Expect mild swelling and redness, with new hair growth starting in 3 to 6 months.
Do I need to take time off work after a hair transplant? Most people take 2 to 14 days off work after a hair transplant.

learn Scalp Micropigmentation

What should I expect after the scalp micropigmentation procedure? Expect redness and swelling initially, with color softening and peeling over 7 to 14 days.

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Experts

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11
Trichologist
Leola Day
Winston-Salem, NC, United States

Clinics

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31
SMP
No. 14 Hair ClinicSouthampton, England · GB

Leola Day