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5 / 1000+ results![Mechanisms of Disease: selective inhibition of 11β-hydroxysteroid dehydrogenase type 1 as a novel treatment for the metabolic syndrome](/images/research/078792fd-82f1-4864-b02e-63c36c8e98e4/small/15272.jpg)
research Mechanisms of Disease: selective inhibition of 11β-hydroxysteroid dehydrogenase type 1 as a novel treatment for the metabolic syndrome
Blocking the enzyme 11β-HSD1 might help treat obesity and metabolic issues.
![11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17α-hydroxylase/17,20-lyase to produce C11α-derivatives of 21-deoxycortisol and 11-hydroxyandrostenedione in vitro](/images/research/b7800701-25f8-4cd8-bfab-bd071e9be6a6/small/13469.jpg)
research 11α-Hydroxyprogesterone, a potent 11β-hydroxysteroid dehydrogenase inhibitor, is metabolised by steroid-5α-reductase and cytochrome P450 17α-hydroxylase/17,20-lyase to produce C11α-derivatives of 21-deoxycortisol and 11-hydroxyandrostenedione in vitro
11α-Hydroxyprogesterone is changed into different substances by certain enzymes and may play a role in prostate cancer.
![Skin steroidogenesis in health and disease](/images/research/38c91137-04e7-4c70-8ca1-baac66c18b75/small/14111.jpg)
research Skin steroidogenesis in health and disease
The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
![Endocrine systems of the skin](/images/research/80dc4718-1251-43dd-a5ae-d45b99166131/small/20915.jpg)
research Endocrine systems of the skin
The skin acts like an endocrine organ, making hormones that affect skin diseases and respond to stress.
![11β-Hydroxysteroid Dehydrogenase Type 1 Inhibition Attenuates the Adverse Effects of Glucocorticoids on Dermal Papilla Cells](/images/research/8c999848-a7d9-4af6-9dae-d6804bbba1ab/small/16042.jpg)
research 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibition Attenuates the Adverse Effects of Glucocorticoids on Dermal Papilla Cells
Blocking 11β-HSD1 can lessen the harmful effects of glucocorticoids on hair growth cells.
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5 / 542 resultscommunity 11 Years into Hair loss battle: ALMOST LOST
The user shared their 11-year journey battling hair loss, highlighting the importance of consistent treatment and avoiding common mistakes. Treatments included minoxidil, finasteride, derma rolling, ketoconazole, multivitamins, and a hair transplant.
community 11 weeks post op !!!! What you think ?
A user shared their 11-week post-op hair transplant results, noting they use only vitamins, not minoxidil or finasteride. Replies suggest starting finasteride to maintain results, with mixed opinions on the current progress.
community 11 months of 1.5 mg Finasteride with blood samples
A user took 1.5 mg Finasteride and topical Minoxidil for 11 months, resulting in significant changes in blood values but no noticeable hair improvement. They experienced side effects like mood swings and increased visceral fat, leading them to stop Finasteride.
community 11 Months progress, 23/June/2023-12/May/2024
The user reported 11 months of hair loss treatment progress, using finasteride, minoxidil, and later dutasteride. They observed hair thickening and a stop in shedding around January 2024.
community 11.Nov to 1.Apr progress. Oral
A user shared progress pictures showing hair regrowth after using a homemade oral solution of 1 mg dutasteride and 2.5 mg minoxidil. Commenters noted significant improvement and increased body hair.