Symptomatic Zinc Deficiency in a Full-Term Breast-Fed Infant

    June 2010 in “ Dermatology Online Journal
    Sambasiviah Chidambara Murthy, Malleshappa M Udagani, Ashok Badakali, Bhuvaneshwari C Yelameli
    Studysummary This report describes a case of hypozincemia type-II in an exclusively breast-fed infant, which resolved with zinc therapy and weaning, highlighting genetic factors in zinc transporter gene SLC30A2.
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    A nine-month-old breast-fed infant presented with skin eruptions, sparse hair growth, and diarrhea, which were indicative of zinc deficiency (hypozincemia type-II). The condition improved rapidly with zinc supplementation and weaning from breastfeeding, confirming the diagnosis. The study highlighted that a mutation in the zinc transporter gene SLC30A2 (ZnT-2) in mothers could lead to this deficiency in infants. The report emphasized the importance of recognizing and treating zinc deficiency in exclusively breast-fed infants to prevent prolonged morbidity.
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