Detection of Nitrite in Water Using Minoxidil as a Reagent

June 2013 in “ Journal of Chemical Education ”

Mario González-Jiménez, Jorge Arenas-Valgañón, Isaac F. Céspedes-Camacho, Juan García-Prieto, Emilio Calle, Julio Casado

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Studysummary This study reports an easy colorimetric method for detecting nitrite in water using minoxidil, which may be suitable for various analytical applications due to its effective detection range.

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This paper presents a colorimetric experiment for detecting nitrite in water using minoxidil as a reagent. Minoxidil is a drug used to treat hair loss and produces a yellow product when reacted with nitrite in acidic media. The experiment is simple, inexpensive, and suitable for environmental, food, and physiological analytical applications. The authors suggest that the experiment can be used as a pedagogical tool to enhance students' curiosity, prediction capacity, and creativity.

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research Aromatic C-Nitrosation of a Bioactive Molecule: Nitrosation of Minoxidil

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Minoxidil reacts to nitrosation 7 times more than phenol, mainly due to its -NH₂ groups, leading to the creation of N-nitrosominoxidil.

research From Surgery to Pharmacology to Gene Therapy: The Evolution of Hair Restoration Techniques

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This article reviews recent advancements in understanding hair follicle biology, with a focus on the potential for gene therapy in treating alopecia, but it reports no new research findings.

research The History of the Development of Minoxidil

23 citations , October 1988 in “Clinics in Dermatology”

Minoxidil was first made for high blood pressure, but it was later found to help hair growth.