White Hair Follicles in Alopecia Areata
December 2024
in “
Minia Journal of Medical Research
”
New to Alopecia Areata? There is a guide in the encyclopedia. Read the guide → Studysummary In this study, researchers found that alopecia areata patches with white hair follicles showed a significant decline in Sox10 marker expression compared to patches without white hairs, while other melanocytic markers were similarly expressed in both groups. Our plain-language summary of this paper — not a Tressless recommendation.
The study investigated white hair follicles in alopecia areata (AA) patches, focusing on their melanocytic components. Conducted at Minia University Hospitals, biopsies were taken from AA patients, with group 1 having white hair follicles and group 2 without. The biopsies were stained for melanocytic markers Sox 10, CD117, Melan A, and HMB-45. Results showed that while most melanocytic markers were expressed in both groups, there was a significant decline in the expression of the Sox10 marker in the white hair group. This suggests a potential link between reduced Sox10 expression and the presence of white hair follicles in AA.
