UVEITIS WITH POLIOSIS, VITILIGO, ALOPECIA AND DYSACOUSIA (VOGT-KOYANAGI SYNDROME)
September 1942
in “
Archives of ophthalmology
”
TLDR Vogt-Koyanagi syndrome often leads to partial or complete blindness and responds poorly to treatment.
Vogt-Koyanagi syndrome is a recognized clinical condition characterized by severe bilateral uveitis, poliosis, vitiligo, alopecia, and dysacousia. The disease has a prolonged course, responds poorly to treatment, and often results in partial or complete blindness. First reported by Vogt in 1906 and later detailed by Koyanagi in 1929, the syndrome involves spontaneous uveitis with associated hair and skin depigmentation, hair loss, and hearing disturbances.