Unusual Diffuse Hair Loss in a 35-Year-Old Taiwanese Man

    December 2008 in “ 中華皮膚科醫學雜誌
    Jonathan Te-Peng Tseng, Tsung-Yen Tsai
    TLDR The man's hair loss was due to syphilis, and his hair regrew after treatment.
    A 35-year-old Taiwanese man experienced gradual diffuse hair loss on his scalp and eyebrows over 2 months, following a transient maculopapular eruption after an influenza vaccination. Despite initial treatment with 5% minoxidil, his condition worsened. Blood tests revealed syphilis, confirmed by a positive Treponema pallidum hemagglutination assay and a high RPR titer. After treatment with benzathine benzylpenicillin, the patient showed significant hair regrowth within 2 months and a reduction in RPR titer, indicating successful treatment of the underlying syphilis.
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